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Source: Atherosclerosis
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Total 2124 results found since Jan 2013.
The prevalence and prognosis of asymptomatic intracranial atherosclerosis in a community-based population: Results based on high-resolution magnetic resonance imaging
CONCLUSIONS: We found that ICAD detected using HR-MRI increases the long-term risk of a first-ever ischemic stroke in a stroke-free population, suggesting that the current primary prevention protocol of stroke awaits further optimization.PMID:37738517 | DOI:10.1111/ene.16057
Source: Atherosclerosis - September 22, 2023 Category: Cardiology Authors: Shengde Li Mingyu Tang Dingding Zhang Fei Han Lixin Zhou Ming Yao Mingli Li Liying Cui Shuyang Zhang Bin Peng Zhengyu Jin Yicheng Zhu Jun Ni Source Type: research
French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children
Rev Med Interne. 2023 Sep 19:S0248-8663(23)00711-7. doi: 10.1016/j.revmed.2023.08.004. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a chronic autoimmune disease involving vascular thrombosis and/or obstetric morbidity and persistent antibodies to phospholipids or certain phospholipid-associated proteins. It is a rare condition in adults and even rarer in children. The diagnosis of APS can be facilitated by the use of classification criteria based on a combination of clinical and biological features. APS may be rapidly progressive with multiple, often synchronous thromboses, resulting in life-threatening...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Z Amoura B Bader-Meunier C Bal Dit Sollier A Belot Y Benhamou H Bezanahary F Cohen N Costedoat-Chalumeau L Darnige L Drouet E Elefant A Harroche M Lambert T Martin I Martin-Toutain A Mathian A Mekinian M Pineton De Chambrun L de Pontual D Wahl C Yelnik S Source Type: research
A cardiovascular polypill for secondary stroke prevention in a tertiary centre in Ghana (SMAART): a phase 2 randomised clinical trial
Lancet Glob Health. 2023 Oct;11(10):e1619-e1628. doi: 10.1016/S2214-109X(23)00347-9.ABSTRACTBACKGROUND: A cardiovascular polypill containing generic drugs might facilitate sustained implementation of and adherence to evidence-based treatments, especially in resource-limited settings. However, the impact of a cardiovascular polypill in mitigating atherosclerotic risk among stroke survivors has not been assessed. We aimed to compare a polypill regimen with usual care on carotid intima-media thickness (CIMT) regression after ischaemic stroke.METHODS: In SMAART, a phase 2 parallel, open-label, assessor-masked, randomised clini...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Fred Stephen Sarfo Jenifer Voeks Sheila Adamu Benedict Apaw Agyei Manolo Agbenorku Nyantakyi Adu-Darko Mercy Adomah Oteng Vida Obese Rexford Adu Gyamfi Nathaniel Adusei Mensah Raelle Tagge Michael Ampofo Samuel Amoabeng Kontoh Samuel Blay Nguah Bruce Ovbi Source Type: research
Particulate matter air pollution is a significant risk factor for cardiovascular disease
This article discusses PM2.5 effects on the cardiovascular and pulmonary systems, specific PM2.5 pathophysiologic mechanisms contributing to cardiopulmonary disease, and preventive measures to limit the cardiovascular and pulmonary effects of PM2.5.PMID:37734693 | DOI:10.1016/j.cpcardiol.2023.102094
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Robert J Henning Source Type: research
Triglyceride-glucose index and the risk of stroke in American adults: findings from the atherosclerosis risk in communities study
CONCLUSIONS: The TyG index independently predict stroke progression.PMID:37723527 | DOI:10.1186/s13098-023-01161-3
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Xinyi Wang Qiyu Liu Tongxin Wang Wende Tian Xuanye Chen Jie Zhang Qiuyi Li Dan Ma Lin Zhao Zhuo Chen Hao Xu Keji Chen Source Type: research
Angiography-based hemodynamic features predict recurrent ischemic events after angioplasty and stenting of intracranial vertebrobasilar atherosclerotic stenosis
CONCLUSIONS: In patients with intracranial vertebrobasilar atherosclerosis treated with PTAS, preprocedural prolonged TTP of the target vessel and shortened trans-stenotic TTP difference were associated with stroke relapse. Q-DSA-defined hemodynamic parameters provided incremental predictive value over conventional parameters for stroke recurrence.CLINICAL RELEVANCE STATEMENT: Quantitative DSA analysis enables intuitive observation and semi-quantitative evaluation of peri-therapeutic cerebral blood flow. More importantly, quantitative DSA-defined hemodynamic parameters have the potential for risk stratification of patients...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Kangmo Huang Weihe Yao Mingming Zha Shanmei Qin Yingle Li Yan Xu Rui Liu Ruidong Ye Yunfei Han Wusheng Zhu Zhongzhao Teng Juan Du Xinfeng Liu Source Type: research
Association of thyroid peroxidase antibody with the RNF213 p.R4810K variant in ischemic stroke/transient ischemic attack
CONCLUSIONS: Elevated TPO-Ab levels may be significantly associated with presence of the RNF213 p. R4810K variant in IS/TIA patients. Thus, TPO-Ab may inherently modify IS/TIA development in RNF213 p. R4810K variant carriers.PMID:37722316 | DOI:10.1016/j.atherosclerosis.2023.117281
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Takeshi Yoshimoto Hiroyuki Ishiyama Yorito Hattori Kunihiro Nishimura Yoko Okada Hideaki Watanabe Yasumasa Ohyagi Yasuhisa Akaiwa Tomoyuki Miyamoto Michi Kawamoto Masahiko Ichijo Hiroyasu Inoue Noriyuki Matsukawa Toshiki Mizuno Hirofumi Matsuyama Hidekazu Source Type: research
Atherosclerosis as a Risk Factor for IBD: A Population-Based Case-Control Study
CONCLUSIONS: A history of an atherosclerotic-related condition is associated with increased odds of developing IBD, particularly among older adults. Future studies should investigate whether drugs targeting atherosclerotic-related inflammation may prevent IBD in higher-risk individuals.PMID:37721310 | DOI:10.14309/ajg.0000000000002502
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Adam S Faye Jordan Axelrad Jiangwei Sun Jonas Halfvarson Jonas S öderling Ola Ol én Jonas F Ludvigsson Source Type: research
Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions
Microsyst Nanoeng. 2023 Sep 15;9:114. doi: 10.1038/s41378-023-00589-x. eCollection 2023.ABSTRACTThe ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically organized vascular network. Defective flow responses, in particular related to high flow conditions, have been associated with atherosclerosis, stroke, arteriovenous malformations, and neurodegenerative diseases. Yet, the molecular mechanisms involved in high flow response are still poorly understood. Here, we described the development and validation of a 96-wells fluidic system, w...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Catarina Gon çalves Fonseca V ânia Silvério David Barata Wolfgang Giese Holger Gerhardt Susana Cardoso Claudio Areias Franco Source Type: research
Atherosclerosis as a Risk Factor for IBD: A Population-Based Case-Control Study
CONCLUSIONS: A history of an atherosclerotic-related condition is associated with increased odds of developing IBD, particularly among older adults. Future studies should investigate whether drugs targeting atherosclerotic-related inflammation may prevent IBD in higher-risk individuals.PMID:37721310 | DOI:10.14309/ajg.0000000000002502
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Adam S Faye Jordan Axelrad Jiangwei Sun Jonas Halfvarson Jonas S öderling Ola Ol én Jonas F Ludvigsson Source Type: research
Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions
Microsyst Nanoeng. 2023 Sep 15;9:114. doi: 10.1038/s41378-023-00589-x. eCollection 2023.ABSTRACTThe ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically organized vascular network. Defective flow responses, in particular related to high flow conditions, have been associated with atherosclerosis, stroke, arteriovenous malformations, and neurodegenerative diseases. Yet, the molecular mechanisms involved in high flow response are still poorly understood. Here, we described the development and validation of a 96-wells fluidic system, w...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Catarina Gon çalves Fonseca V ânia Silvério David Barata Wolfgang Giese Holger Gerhardt Susana Cardoso Claudio Areias Franco Source Type: research
Higher habitual dietary intakes of flavanols and anthocyanins differentially associate with lower incidence of ischemic stroke subtypes-A follow-up analysis
CONCLUSIONS: Higher habitual intakes of flavanols and anthocyanins are differentially associated with lower risk of ischemic stroke from atherosclerosis and/or cardioembolism, but not with other subtypes.PMID:37716608 | DOI:10.1016/j.tjnut.2023.09.011
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Benjamin H Parmenter Pratik Pokharel Frederik Dalgaard Kevin Murray Aed ín Cassidy Catherine P Bondonno Joshua R Lewis Cecilie Kyr ø Anne Tj ønneland Kim Overvad Jonathan M Hodgson Nicola P Bondonno Source Type: research
