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Condition: Heart Attack
Nutrition: Diets
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Total 559 results found since Jan 2013.
Evaluation of anti-atherosclerotic effects of Sitagliptin via modulation of the mTOR pathway in male rabbits
This study aimed to investigate the effect of Sitagliptin on the progression of atherosclerosis. Twenty-one male New Zealand White rabbits weighing 2-2.5 kg each were split into three groups: normal control, atherogenic control, and Sitagliptin-treated. The following parameters: serum triglycerides (TG), total cholesterol (TC), LDL, and a tissue autophagy marker (p62) using ELISA, aortic mRNA expression of mTORC1 marker using Real-Time Quantitative PCR(RT-qPCR), and histological inspection of the aorta were assessed. The mRNA expression of mTORC1 and the lipid profile of aortic tissue are considerably elevated in atherogen...
Source: Journal of Medicine and Life - May 11, 2023 Category: General Medicine Authors: Hussam Hamza Sahib Bassim Mohammad Najah Rayish Hadi Source Type: research
Heterozygosity for ADP-ribosylation factor 6 suppresses the burden and severity of atherosclerosis
PLoS One. 2023 May 10;18(5):e0285253. doi: 10.1371/journal.pone.0285253. eCollection 2023.ABSTRACTAtherosclerosis is the root cause of major cardiovascular diseases (CVD) such as myocardial infarction and stroke. ADP-ribosylation factor 6 (Arf6) is a ubiquitously expressed GTPase known to be involved in inflammation, vascular permeability and is sensitive to changes in shear stress. Here, using atheroprone, ApoE-/- mice, with a single allele deletion of Arf6 (HET) or wildtype Arf6 (WT), we demonstrate that reduction in Arf6 attenuates atherosclerotic plaque burden and severity. We found that plaque burden in the descending...
Source: Atherosclerosis - May 10, 2023 Category: Cardiology Authors: Venkateswara R Gogulamudi Md Torikul Islam Jessica R Durrant Adelola O Adeyemo Daniel W Trott Mi Ho Hyuhn Weiquan Zhu Anthony J Donato Ashley E Walker Lisa A Lesniewski Source Type: research
The effect of bempedoic acid an ATP-citrate lyase inhibitor on cardiovascular risk factors in rats with experimentally induced myocardial infarction and hyperlipidemia
Cell Mol Biol (Noisy-le-grand). 2022 Sep 30;68(10):94-99. doi: 10.14715/cmb/2022.68.10.15.ABSTRACTControl of hyperlipidemia is believed to reduce major cardiovascular events such as cardiovascular death, myocardial infarction, nonfatal stroke, hospitalization for unstable angina, and coronary revascularization. The benefits of monotherapy with Bempedoic acid (BA) as a hypolipidemic agent given after induction of myocardial infarction (MI) in reducing the risk of acute MI worth being investigated, therefore this study was designed to investigate the effectiveness of Bempedoic acid on reducing cardiovascular risk factors in ...
Source: Cellular and Molecular Biology - April 28, 2023 Category: Molecular Biology Authors: Mahmood Salim Yaseen Nidhal Mohammed Ali Source Type: research
Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters.
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Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news
High-Salt Diet a Danger Even With Normal Blood Pressure
A large study shows eating a diet high in salt is linked to clogged arteries of the heart and neck, raising the risk of heart attack and stroke, even in people with normal blood pressure.
Source: WebMD Health - April 10, 2023 Category: Consumer Health News Source Type: news
Mediterranean diet ‘can reduce heart attacks in people at higher risk’
First study of its kind finds diet can benefit hundreds of millions with obesity, diabetes or other risk factorsA Mediterranean diet can lower the risk of a heart attack, stroke or early death for hundreds of millions of people who have an increased possibility of cardiovascular disease, a global review of evidence suggests.A diet rich in olive oil, nuts, seafood, whole grains and vegetables has previously been linked to a number of benefits, and its effectiveness in helping healthy people to live longer is well known.Continue reading...
Source: Guardian Unlimited Science - March 29, 2023 Category: Science Authors: Andrew Gregory Health editor Tags: Food science Medical research Health & wellbeing Diets and dieting Heart attack Diabetes Life and style Society Source Type: news
