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Total 9563 results found since Jan 2013.
Rheumatic Mitral Valve Disease Is Associated With Worse Outcomes in Stroke Clinical Sciences
We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored. Data were obtained from a National Insurance Database. All hospitalized strokes between October 1, 2004, and January 31, 2013, were included in the current study. Characteristics and outcomes were compared for RMVD and non-RMVD patients. Logistic regression, propensity score matching, and multivariate models were used to assess study outcomes.Resultsā...
Source: Stroke - October 23, 2016 Category: Neurology Authors: Wood, A. D., Mannu, G. S., Clark, A. B., Tiamkao, S., Kongbunkiat, K., Bettencourt-Silva, J. H., Sawanyawisuth, K., Kasemsap, N., Barlas, R. S., Mamas, M., Myint, P. K. Tags: Rheumatic Heart Disease, Valvular Heart Disease, Complications, Mortality/Survival, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Stroke Thrombolysis in a Centralized and a Decentralized System (Helsinki and Telemedical Project for Integrative Stroke Care Network) Clinical Sciences
Background and PurposeāIntravenous thrombolysis with tissue-type plasminogen activator (tPA) for acute ischemic stroke is more effective when delivered early. Timely delivery is challenging particularly in rural areas with long distances. We compared delays and treatment rates of a large, decentralized telemedicine-based system and a well-organized, large, centralized single-hospital system.MethodsāWe analyzed the centralized system of the Helsinki University Central Hospital (Helsinki and Province of Uusimaa, Finland, 1.56 million inhabitants, 9096 km2) and the decentralized TeleStroke Unit network in a predominantly ...
Source: Stroke - November 27, 2016 Category: Neurology Authors: Gordian J. Hubert, Atte Meretoȷa, Heinrich J. Audebert, Turgut Tatlisumak, Florian Zeman, Sandra Boy, Roman L. Haberl, Markku Kaste, Peter Muller–Barna Tags: Revascularization, Treatment, Health Services, Ischemic Stroke Original Contributions Source Type: research
Tissue-Selective Salvage of the White Matter by Successful Endovascular Stroke Therapy Clinical Sciences
This study examines occurrence, determinants, and clinical significance of such effects.MethodsāThree hundred twenty-two patients with acute middle cerebral artery occlusion subjected to mechanical thrombectomy were included. Infarct patterns were categorized into WMā (sparing the WM) and WM+ (involving WM). National Institutes of Health Stroke Scaleābased measures of neurological outcome, including National Institutes of Health Stroke Scale improvement or National Institutes of Health Stroke Scale worsening, good functional midterm outcome (day 90-modified Rankin Scale score of ā¤2), the occurrence of malignant swe...
Source: Stroke - September 25, 2017 Category: Neurology Authors: Justus F. Kleine, Mirjam Kaesmacher, Benedikt Wiestler, Johannes Kaesmacher Tags: Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research
Comorbid Psychiatric Disease Is Associated With Lower Rates of Thrombolysis in Ischemic Stroke Brief Report
Background and PurposeāIntravenous thrombolysis (IVT) improves outcomes after acute ischemic stroke but is underused in certain patient populations. Mental illness is pervasive in the United States, and patients with comorbid psychiatric disease experience inequities in treatment for a range of conditions. We aimed to determine whether comorbid psychiatric disease is associated with differences in IVT use in acute ischemic stroke.MethodsāAcute ischemic stroke admissions between 2007 and 2011 were identified in the Nationwide Inpatient Sample. Psychiatric disease was defined by International Classification of Diseases, ...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Diana M. Bongiorno, Gail L. Daumit, Rebecca F. Gottesman, Roland Faigle Tags: Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research
Endovascular Clot Retrieval Therapy: Implications for the Organization of Stroke Systems of Care in North America Understanding and Applying the Endovascular Trials
Endovascular acute ischemic stroke therapy is now proven by randomized controlled trials to produce large, clinically meaningful benefits. In response, stroke systems of care must change to increase timely and equitable access to this therapy. In this review, we provide a North American perspective on implications for stroke systems, focusing on the United States and Canada, accompanied by initial recommendations for changes. Most urgently, every community must create access to a hospital that can safely and quickly provide intravenous tissue-type plasminogen activator and immediately transfer appropriate patients onward t...
Source: Stroke - May 22, 2015 Category: Neurology Authors: Smith, E. E., Schwamm, L. H. Tags: Health policy and outcome research, Acute Cerebral Infarction, Acute Stroke Syndromes, Angioplasty and Stenting Understanding and Applying the Endovascular Trials Source Type: research
Timing of Percutaneous Endoscopic Gastrostomy for Acute Ischemic Stroke Clinical Sciences
Background and PurposeāStroke guidelines recommend time-limited trials of nasogastric feeding prior to percutaneous endoscopic gastrostomy (PEG) tube placement. We sought to describe timing of PEG placement and identify factors associated with early PEG for acute ischemic stroke.MethodsāWe designed a retrospective observational study to examine time to PEG for ischemic stroke admissions in the Nationwide Inpatient Sample, 2001 to 2011. We defined early PEG placement as 1 to 7 days from admission. Using multivariable regression analysis, we identified the effects of patient and hospital characteristics on PEG timing.Res...
Source: Stroke - January 22, 2017 Category: Neurology Authors: Benjamin P. George, Adam G. Kelly, George P. Albert, David Y. Hwang, Robert G. Holloway Tags: Health Services, Ischemic Stroke Original Contributions Source Type: research
Prehospital Emergency Care in Childhood Arterial Ischemic Stroke Brief Report
Background and PurposeāImmediately calling an ambulance is the key factor in reducing time to hospital presentation for adult stroke. Little is known about prehospital care in childhood arterial ischemic stroke (AIS). We aimed to determine emergency medical services call-taker and paramedic diagnostic sensitivity and to describe timelines of care in childhood AIS.MethodsāThis is a retrospective study of ambulance-transported children aged
Source: Stroke - March 27, 2017 Category: Neurology Authors: Belinda Stojanovski, Paul T. Monagle, Ian Mosley, Leonid Churilov, Fiona Newall, Grant Hocking, Mark T. Mackay Tags: Basic Science Research, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research
Dolichoectasia and Small Vessel Disease in Young Patients With Transient Ischemic Attack and Stroke Clinical Sciences
Background and PurposeāWe evaluated whether basilar dolichoectasia is associated with markers of cerebral small vessel disease in younger transient ischemic attack and ischemic stroke patients.MethodsāWe used data from the SIFAP1 study (Stroke in Young Fabry Patients), a large prospective, hospital-based, screening study for Fabry disease in young (
Source: Stroke - August 28, 2017 Category: Neurology Authors: Vincent Thijs, Ulrike Grittner, Franz Fazekas, Dominick J.H. McCabe, Anne-Katrin Giese, Christof Kessler, Peter Martus, Bo Norrving, Erich Bernd Ringelstein, Reinhold Schmidt, Christian Tanislav, Jukka Putaala, Turgut Tatlisumak, Bettina von Sarnowski, Ar Tags: Hypertension, Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA), Vascular Disease Original Contributions Source Type: research
Ischemic Stroke Profile, Risk Factors, and Outcomes in India Brief Report
Background and PurposeāThe Indo-US Collaborative Stroke Project was designed to characterize ischemic stroke across 5 high-volume academic tertiary hospitals in India.MethodsāFrom January 2012 to August 2014, research coordinators and physician coinvestigators prospectively collected data on 2066 patients with ischemic stroke admitted
Source: Stroke - December 22, 2017 Category: Neurology Authors: P.N. Sylaja, Jeyaraj Durai Pandian, Subhash Kaul, M.V. Padma Srivastava, Dheeraj Khurana, Lee H. Schwamm, Praveen Kesav, Deepti Arora, Aman Pannu, Tijy K. Thankachan, Aneesh B. Singhal Tags: Ischemic Stroke Brief Reports Source Type: research
Posttreatment National Institutes of Health Stroke Scale Is Superior to the Initial Score or Thrombolysis in Cerebral Ischemia for 3-Month Outcome Clinical Sciences
Background and PurposeāThe majority of ischemic stroke patients receiving endovascular recanalization therapy (EVT) experience variable changes of neurological severities during the hyperacute period. We hypothesized that the National Institutes of Health Stroke Scale (NIHSS) score after EVT is a better prognostic factor compared with the initial NIHSS score or revascularization status.MethodsāWe identified 566 stroke patients who received EVT at Seoul National University Bundang Hospital between April 2008 and December 2015. We prospectively collected post-EVT NIHSS score, which was measured in the angiography suite b...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Han-Gil Jeong, Beom Joon Kim, Jay Chol Choi, Keun-Sik Hong, Mi Hwa Yang, Cheolkyu Jung, Moon-Ku Han, Hee-Joon Bae Tags: Ischemic Stroke Original Contributions Source Type: research
Academic Year-end Changeover and Stroke Outcomes
Lower quality of care and poorer outcomes are suspected when new trainees (eg, residents) start in July in teaching hospitals, the so-called āthe July effect.ā We evaluated outcomes and processes of care among patients with an acute ischemic stroke (AIS) admitted in July versus other 11 months of the year.
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2014 Category: Neurology Authors: Tai Hwan Park, Donald A. Redelmeier, Shudong Li, Jitphapa Pongmoragot, Gustavo Saposnik, Investigators of the Registry of the Canadian Stroke network (RCSN) for the Stroke Outcomes Research (SORCan) Working Group Source Type: research
Profile and 1-Year Outcome of Ischemic Stroke in East China: Nanjing First Hospital Stroke Registry
This study aimed to investigate the profile and outcome after 1-year follow-up of AIS in East China.
Source: Journal of Stroke and Cerebrovascular Diseases - September 22, 2015 Category: Neurology Authors: Guo-mei Shi, Ying-dong Zhang, Cong Geng, Yu-qiao Zhang, Xi-ding Pan, Yu-kai Liu, Jie Yang, Jun-shan Zhou, Nanjing First Hospital Stroke Registry Investigators Source Type: research
Impact of Rehabilitation on Outcomes in Patients With Ischemic Stroke Clinical Sciences
Background and PurposeāWe aimed to examine the concurrent effects of timing and intensity of rehabilitation on improving activities of daily living (ADL) among patients with ischemic stroke.MethodsāUsing the Japanese Diagnosis Procedure Combination inpatient database, we retrospectively analyzed consecutive patients with ischemic stroke at admission who received rehabilitation (n=100ā719) from April 2012 to March 2014. Early rehabilitation was defined as that starting within 3 days after admission. The average rehabilitation intensity per day was calculated as the total units of rehabilitation during hospitalization ...
Source: Stroke - February 26, 2017 Category: Neurology Authors: Maiko Yagi, Hideo Yasunaga, Hiroki Matsui, Kojiro Morita, Kiyohide Fushimi, Masashi Fujimoto, Teruyuki Koyama, Junko Fujitani Tags: Ischemic Stroke Original Contributions Source Type: research
Distribution and Temporal Trends From 1993 to 2015 of Ischemic Stroke Subtypes Clinical Sciences
Background and PurposeāPreventive strategies, together with demographic and socioeconomic changes, might have modified the worldwide distribution of ischemic stroke (IS) subtypes. We investigated those changes by means of a systematic review and meta-analysis.MethodsāWe evaluated all population- and hospital-based studies reporting the distribution of IS etiologic subtypes according to the TOAST criteria (Trial of ORG 10172 in Acute Stroke Treatment). Studies were identified by searching articles indexed on PubMed and Scopus from January 1, 1993, to June 30, 2017. Two independent investigators extracted data and checke...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Raffaele Ornello, Diana Degan, Cindy Tiseo, Caterina Di Carmine, Laura Perciballi, Francesca Pistoia, Antonio Carolei, Simona Sacco Tags: Epidemiology, Race and Ethnicity, Meta Analysis, Ischemic Stroke Original Contributions Source Type: research
Age-Specific Associations of Renal Impairment With Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Transient Ischemic Attack and Stroke Clinical Sciences
Background and PurposeāIt has been hypothesized that cerebral small vessel disease (SVD) and chronic renal impairment may be part of a multisystem small-vessel disorder, but their association may simply be as a result of shared risk factors (eg, hypertension) rather than to a systemic susceptibility to premature SVD. However, most previous studies were hospital based, most had inadequate adjustment for hypertension, many were confined to patients with lacunar stroke, and none stratified by age.MethodsāIn a population-based study of transient ischemic attack and ischemic stroke (OXVASC [Oxford Vascular Study]), we evalu...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Bian Liu, Kui Kai Lau, Linxin Li, Caroline Lovelock, Ming Liu, Wilhelm Kuker, Peter M. Rothwell Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
