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Mechanisms of in-hospital acute ischemic stroke and their relevance to prognosis: A retrospective analysis
In-hospital stroke (IHS) refers to stroke that occurs during hospitalization in patients admitted for other diagnoses,1 of which ischemic stroke is the most common type, accounting for approximately 60% to 89%.2,3 IHS is common with approximately 35,000 to 75,000 patients having a stroke while hospitalized in the United States each year.4 The incidence of IHS tends to increase per year,5 resulting in a serious social burden. In-hospital ischemic strokes are widely distributed across various in-hospital departments.
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2023 Category: Neurology Authors: Juanjuan Wu, Guangsong Han, Yuhui Sha, Mingyu Tang, Ziang Pan, Ziyue Liu, Yicheng Zhu, Lixin Zhou, Jun Ni Source Type: research

Recurrent stroke arrival time
Stroke patients and family members should receive stroke education including recognition of stroke symptoms and prompt activation of emergency medical services (EMS). The impact of this education is unclear. We aimed to measure the associations between EMS use and timing of hospital arrival and first-ever and recurrent strokes as a proxy for stroke education.
Source: Journal of Stroke and Cerebrovascular Diseases - April 8, 2023 Category: Neurology Authors: Braydon L Dymm, Madeline Kwicklis, William J Meurer, Xu Shi, Lynda D Lisabeth Source Type: research

Hospital Discharge and Readmissions Before and During the COVID-19 Pandemic for California Acute Stroke Inpatients
Stroke is a leading cause of death and disability in the United States, with approximately 795,000 new strokes occurring annually, including acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH).1 The Coronavirus Disease 2019 (COVID-19) pandemic has impacted all levels of care for stroke patients, such as delays in initial presentation, reduction in acute therapies, limitations of in-patient resources, delays or lack of initiation of secondary stroke prevention therapy, and limitations in rehabilitation services after hospital discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2023 Category: Neurology Authors: George P. Albert, Daryl C. McHugh, Debra E. Roberts, Adam G. Kelly, Remi Okwechime, Robert G. Holloway, Benjamin P. George Source Type: research

Clinical validation of in-hospital stroke diagnosis
The objective was to validate the diagnostic accuracy of in-hospital stroke identification in stroke audit data at a large teaching hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - August 5, 2023 Category: Neurology Authors: Lucy Chapman, Orla Kennedy, David Bradley, Joseph Harbison Source Type: research

Characteristics, management and outcome of stroke: Observations from the Sri Lanka Stroke Clinical Registry
We report data from the initial phase of a nationally representative hospital-based stroke registry in Sri Lanka.
Source: Journal of Stroke and Cerebrovascular Diseases - August 13, 2023 Category: Neurology Authors: Padma Sriyani Gunaratne, Vijayabala Jeevagan, Senaka Bandusena, Ahamed Ismail Ahamed Ziyad, Champika Wickramasinghe, Carukshi Arambepola, Thashi Chang Source Type: research

Racial and Ethnic Disparities in the Use of Intravenous Recombinant Tissue Plasminogen Activator and Outcomes for Acute Ischemic Stroke
This study investigated possible racial and ethnic disparities in the administration and outcome of recombinant tissue plasminogen activator (rtPA) therapy for acute ischemic stroke in whites, blacks, Hispanics, and Asian/Pacific Islanders. Using the National Inpatient Sample for 2001-2008, we selected patients with a primary diagnosis of acute ischemic stroke who received treatment with rtPA. Patient data were stratified by race (white, black, Hispanic, and Asian/Pacific Islander). We analyzed the association of patient race on rtPA utilization rate, in-hospital morbidity (ie, discharge to long-term facility), intracrania...
Source: Journal of Stroke and Cerebrovascular Diseases - December 12, 2011 Category: Neurology Authors: Deena M. Nasr, Waleed Brinjikji, Harry J. Cloft, Alejandro A. Rabinstein Tags: Original Articles Source Type: research

First Stroke Patients In Florida Treated In UM Stem Cell Trial
The first two stroke patients have been enrolled in a phase 2 clinical trial of a revolutionary new treatment for ischemic stroke being conducted at the University of Miami/Jackson Memorial Hospital. The trial, using a patient's own bone marrow stem cells, is the first intra-arterial stroke stem cell trial in the U.S., and the two UM/Jackson patients are the first in Florida to participate. Led by Dileep Yavagal, M.D...
Source: Health News from Medical News Today - January 29, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Blocked Heart Arteries May Presage Stroke
Even if you are considered to be at low risk for stroke, having blocked heart arteries can mean you are more likely to have one, says new research published online this week in Stroke, a journal of the American Heart Association. The researchers suggest blocked arteries should be taken into account to the same extent as other known risk factors such as atrial fibrillation when assessing patients' stroke risk. Lead author Dirk M. Hermann is professor of vascular neurology and dementia at the University Hospital Essen in Germany...
Source: Health News from Medical News Today - March 1, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Stroke Risk Tightly Aligned With Coronary Atherosclerosis
This study demonstrates that stroke risk is tightly aligned with coronary atherosclerosis, showing the closely related nature of cardiovascular and cerebrovascular disease," said Dirk M. Hermann, M.D., the study's lead investigator and professor of vascular neurology and dementia at the University Hospital Essen in Germany...
Source: Health News from Medical News Today - March 4, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke
Anemia is a known predictor of in-hospital mortality among patients with such vascular conditions as acute myocardial infarction, congestive heart failure, and chronic kidney disease. The role of anemia in patients with acute ischemic stroke is less well understood. We sought to examine the association between anemia at hospital admission and the combined outcome of in-hospital mortality and discharge to hospice in patients with acute ischemic stroke. We evaluated data from a retrospective cohort of consecutive ischemic stroke patients presenting within 48 hours of symptom onset at 5 hospitals between 1998 and 2003. Anemi...
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2011 Category: Neurology Authors: Jason J. Sico, John Concato, Carolyn K. Wells, Albert C. Lo, Steven E. Nadeau, Linda S. Williams, Aldo J. Peixoto, Mark Gorman, John L. Boice, Dawn M. Bravata Tags: Original Articles Source Type: research

Determinants of Neurologic Deterioration and Stroke-Free Survival After Spontaneous Cervicocranial Dissections: A Multicenter Study
Patients with spontaneous cervicocranial dissection (SCCD) may experience new or recurrent ischemic events despite antiplatelet or anticoagulant therapy. Treatment with stent placement is an available option; however, the literature on patient selection is limited. Thus, identifying patients at high risk for neurologic deterioration after SCCD is of critical importance. The present study examined the rate of neurologic deterioration in medically treated patients with SCCD and evaluated demographic, clinical, and radiologic factors affecting this deterioration. We retrospectively identified consecutive patients with SCCD ov...
Source: Journal of Stroke and Cerebrovascular Diseases - November 15, 2011 Category: Neurology Authors: Ameer E. Hassan, Vikram Jadhav, Haralabos Zacharatos, Saqib A. Chaudhry, Gustavo J. Rodriguez, Yousef M. Mohammad, M. Fareed K. Suri, Nauman Tariq, Gabriela Vazquez, Ramachandra P. Tummala, Robert A. Taylor, Adnan I. Qureshi Tags: Original Articles Source Type: research

Stroke-Related Disabilities May Be Improved By Regenerating Spinal Cord Fibers
A study by researchers at Henry Ford Hospital found "substantial evidence" that a regenerative process involving damaged nerve fibers in the spinal cord could hold the key to better functional recovery by most stroke victims. The findings may offer new hope to those who suffer stroke, the leading cause of long-term disability in adults. Although most stroke victims recover some ability to voluntarily use their hands and other body parts, about half are left with weakness on one side of their bodies, while a substantial number are permanently disabled...
Source: Health News from Medical News Today - May 27, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Quality of Life of Stroke Survivors: A 3-Month Follow-up Study
This study aimed to assess, compare, and identify predictors of unsatisfactory QoL in different dimensions of stroke survivors at 1 month and 3 months poststroke. A total of 125 stroke survivors were recruited from 4 public hospitals under the auspices of the Department of Medical Services, Bangkok Metropolitan Administration, Thailand, and followed for 3 months. QoL was assessed using the self-administered SF-36 Health Survey, version 2.0. Six specific dimensions of QoL—physical function, role-physical, bodily pain, general health, vitality, and role-emotional—were significantly improved at 3 months poststroke; howeve...
Source: Journal of Stroke and Cerebrovascular Diseases - July 2, 2012 Category: Neurology Authors: Sangkaew Rachpukdee, Nopporn Howteerakul, Nawarat Suwannapong, Smarn Tang-aroonsin Tags: Original Articles Source Type: research

Repeated Episodes of Ischemic Stroke over a Short Period in a Patient with Essential Thrombocythemia on Anticoagulant Therapy
A 69-year-old man who had essential thrombocythemia, for which he was taking no medications, suddenly developed aphasia and right hemiplegia and was admitted to the hospital. He was thought to have had an embolic stroke and was initially treated with warfarin. Although the international normalized ratio was in the therapeutic range, he had 3 additional ischemic stroke episodes with the same symptoms after the index stroke. Magnetic resonance angiographic examinations revealed serial changes in middle cerebral artery stenosis. After administration of an antiplatelet agent and hydroxyurea, he had no additional strokes.
Source: Journal of Stroke and Cerebrovascular Diseases - August 14, 2012 Category: Neurology Authors: Masaki Naganuma, Kazuya Isoda, Shinsuke Nishi, Kiyotaka Ito, Teruyuki Hirano Tags: Case Reports Source Type: research

Predicting delirium after a stroke
Clinicians treating patients with stroke will be familiar with delirium: a syndrome characterised by the rapid onset of disorganised thought, inattention and altered level of consciousness, with a characteristically fluctuant course. Limited data suggest that up to a quarter of patients with stroke admitted to hospital are affected at some point.1 In addition to being distressing for patients and carers, delirium doubles the risk of death and dependency.2 If diagnosed correctly, delirium can be treated by searching for precipitating factors such as infection, altering predisposing factors such as medication and taking step...
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 5, 2014 Category: Neurosurgery Authors: Makin, S. D. J., Wardlaw, J. Tags: Open access, Stroke, Delirium, Memory disorders (psychiatry), Disability Editorial commentaries Source Type: research