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Condition: Ischemic Stroke
Management: Hospitals
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Total 2377 results found since Jan 2013.
Breakthrough of modern reperfusion therapies for acute stroke in Lithuania: The importance of integrated government support and national stroke care network
Incidence of ischemic stroke remains high in Lithuania (>10.000 new strokes every year) because of high prevalence and poor control of vascular risk factors. The intravenous thrombolysis (IVT) was started in 2002 in 2 Vilnius hospitals. Since 2007 IVT was recommended as first line treatment for acute ischemic stroke according to national guidelines. Nevertheless, the total annual number of IVTs remained low across the country (lessthan 100 procedures) until 2011. During 2012-2013 number of IVTs increased up to 160 and 207, respectively, however, only few centres in largest two cities were active, and access to IVT and mech...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Dalius Jatuzis, Aleksandras Vilionskis, Daiva Rastenyte Source Type: research
The development of visual management web system for acute ischemic stroke therapy
【Background and Purpose】The benefits of intravenous tissue-plasminogen activator and endovascular therapy in acute ischemic stroke are highly time-dependent. However, there are so many cross-departmental tasks to eligible patent that many stroke centers have difficulty achieving the guideline re commended 1-hour Door-to-Needle time. We developed a visual management web system named “Task Calc. Stroke” to support in-hospital task processing for acute stroke treatment efficacy. We aim to introduce the system and the results of the initial evaluation survey.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Shoji Matsumoto, Hiroshi Koyama, Taketo Hatano, Nobutake Sadamasa, Yasutoshi Kai, Makoto Saka, Tetsuya Hashimoto, Ichiro Nakahara, Izumi Nagata, Jun-ichi Kira Source Type: research
Streamlining Workflow for Endovascular Mechanical Thrombectomy: Lessons Learned from a Comprehensive Stroke Center
Recently, 5 randomized controlled trials confirmed the superiority of endovascular mechanical thrombectomy (EMT) to intravenous thrombolysis in acute ischemic stroke with large-vessel occlusion. The implication is that our health systems would witness an increasing number of patients treated with EMT. However, in-hospital delays, leading to increased time to reperfusion, are associated with poor clinical outcomes. This review outlines the in-hospital workflow of the treatment of acute ischemic stroke at a comprehensive stroke center and the lessons learned in reduction of in-hospital delays.
Source: Journal of Stroke and Cerebrovascular Diseases - June 1, 2017 Category: Neurology Authors: Hongjin Wang, Arthur Thevathasan, Richard Dowling, Steven Bush, Peter Mitchell, Bernard Yan Tags: Review Article Source Type: research
Patterns of Care and Temporal Trends in Ischemic Stroke Management: A Brazilian Perspective
Demonstration of an improvement process of quality indicators in stroke care is essential to obtain certification as a primary stroke center (PSC). Our aim was to evaluate factors that influence temporal trends in quality indicators of ischemic stroke (IS) in a Brazilian hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - June 20, 2017 Category: Neurology Authors: Monique Bueno Alves, Gisele Sampaio Silva, Renata Carolina Acri Miranda, Rodrigo Meireles Massaud, Andreia Maria Heins Vaccari, Miguel Cendoroglo-Neto, Solange Diccini Source Type: research
Influence of Penumbral Reperfusion on Clinical Outcome Depends on Baseline Ischemic Core Volume Clinical Sciences
This study included 1507 patients. Reperfused penumbral volume had moderate ability to predict 90-day mRS 0 to 1 (area under the curve, 0.77; R2, 0.28; P
Source: Stroke - September 25, 2017 Category: Neurology Authors: Chushuang Chen, Mark W. Parsons, Matthew Clapham, Christopher Oldmeadow, Christopher R. Levi, Longting Lin, Xin Cheng, Min Lou, Timothy J. Kleinig, Kenneth S. Butcher, Qiang Dong, Andrew Bivard Tags: Ischemic Stroke Original Contributions Source Type: research
Differential Proteomics for Distinguishing Ischemic Stroke from Controls: a Pilot Study of the SpecTRA Project
AbstractA diagnostic blood test for stroke is desirable but will likely require multiple proteins rather than a single “troponin.” Validating large protein panels requires large patient numbers. Mass spectrometry (MS) is a cost-effective tool for this task. We compared differences in the abundance of 147 protein markers to distinguish 20 acute cerebrovascular syndrome (ACVS) patients who presented to the Emergen cy Department of one urban hospital within< 24 h from onset) and from 20 control patients who were enrolled via an outpatient neurology clinic. We targeted proteins from the stroke literature plus cardio...
Source: Translational Stroke Research - January 24, 2018 Category: Neurology Source Type: research
Delays in the Air or Ground Transfer of Patients for Endovascular Thrombectomy Clinical Sciences
Background and Purpose—For suspected large vessel occlusion patients efficient transfer to centers that provide endovascular therapy (ET) is critical to maximizing treatment opportunity. Our objective was to examine associations between transfer time, modes of transfer, ET, and outcomes within a hub-and-spoke telestroke network.Methods—Patients with ischemic stroke were included if transferred to a single hub hospital between January 2011 and October 2015 with National Institutes of Health Stroke Scale>6, onset
Source: Stroke - May 25, 2018 Category: Neurology Authors: Robert W. Regenhardt, Adam P. Mecca, Stephanie A. Flavin, Gregoire Boulouis, Arne Lauer, Kori Sauser Zachrison, James Boomhower, Aman B. Patel, Joshua A. Hirsch, Lee H. Schwamm, Thabele M. Leslie-Mazwi Tags: Revascularization, Quality and Outcomes, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research
The Serum BDNF Level Offers Minimum Predictive Value for Motor Function Recovery After Stroke
The objective of this study was to investigate the relationship among serum BDNF level, fractional anisotropy (FA), and functional outcome during post-acute stroke rehabilitation. Serum BDNF levels were measured on admission to an acute inpatient rehabilitation hospital. The primary functional outcome was functional independence measure (FIM) motor subscore at discharge. The secondary outcome measures were FIM total score at discharge, FIM motor subscore on admission, length of stay in the hospital, and discharge destination. We investigated the relationship among the level of serum BDNF and FA as well as functional outcom...
Source: Translational Stroke Research - August 3, 2018 Category: Neurology Source Type: research
Trends in Interhospital Transfers and Mechanical Thrombectomy for United States Acute Ischemic Stroke Inpatients
Objective: Stroke care in the US is increasingly regionalized. Many patients undergo interhospital transfer to access specialized, time-sensitive interventions such as mechanical thrombectomy. Methods: Using a stratified survey design of the US Nationwide Inpatient Sample (2009-2014) we examined trends in interhospital transfers for ischemic stroke resulting in mechanical thrombectomy. International Classification of Disease —Ninth Revision (ICD-9) codes were used to identify stroke admissions and inpatient procedures within endovascular-capable hospitals.
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2019 Category: Neurology Authors: Benjamin P. George, Thomas A. Pieters, Christopher G. Zammit, Adam G. Kelly, Kevin N. Sheth, Tarun Bhalla Source Type: research
Nicardipine Associated Risk of Short-Term Mortality in Critically Ill Patients with Ischemic Stroke
This study aimed to determine all-cause in-hospital mortality, medication-related hypotensive episodes, development of hospital acquired infections and hospital length of stay between nicardipine and labetalol use for the management of hypertension after acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2019 Category: Neurology Authors: Mahsa Sadeghi, Hamidreza Saber, Azara Singh, Claudia Hanni, Dennis Parker, Aaron Desai, Wazim Mohamed Source Type: research
The Influence of Stroke Location on Cognitive and Mood Impairment. A Voxel-Based Lesion-Symptom Mapping Study
Background and purpose: The role of stroke location as a determinant of mood and cognitive symptoms is still a matter of debate. The aim of this study was to identify the predictive value of ischemic stroke location, on a voxel basis, for mood and cognitive outcome. Materials and methods: A prospective monocentric study including patients with a supratentorial ischemic stroke was conducted. A 3 Tesla brain MRI was performed at baseline. Mood and cognition were assessed using Hospital Anxiety and Depression scale (HAD), apathy inventory (AI), and Montreal Cognitive Assessment scale subscores, performed at 3 months poststroke.
Source: Journal of Stroke and Cerebrovascular Diseases - February 1, 2019 Category: Neurology Authors: Sharmila Sagnier, Fanny Munsch, Antoine Bigourdan, Sabrina Debruxelles, Mathilde Poli, Pauline Renou, St éphane Olindo, François Rouanet, Vincent Dousset, Thomas Tourdias, Igor Sibon Source Type: research
Clinical Characteristics and Emergent Therapeutic Interventions in Patients Evaluated through the In-hospital Stroke Alert Protocol
Background and Purpose: Emergent evaluation of inpatients with suspected acute ischemic stroke faces difficulty of symptoms recognition, false alarms, and high rate of contraindications to reperfusion therapies. We aim to assess the clinical characteristics and therapeutic interventions implemented in patients evaluated though the in-hospital Stroke Alert Protocol. Methods: We analyzed 4 years-worth of Stroke Alert cases at a university hospital. Demographics, clinical presentation, final diagnosis, and acute interventions were compared between inpatients and those presenting to the emergency department.
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2019 Category: Neurology Authors: Victor J. Del Brutto, Agnieszka Ardelt, Andrea Loggini, Zachary Bulwa, Faten El-Ammar, Raisa C. Martinez, James Brorson, Fernando Goldenberg Source Type: research
Factors Associated with Leukoaraiosis Severity in Acute Stroke Patients
Objective: Age-related cerebral white matter abnormalities, commonly termed leukoaraiosis (LA), are frequent manifestation of cerebral microvascular disease. Aging and hypertension are well linked to LA. We compared additional vascular risk factors and socioeconomic factors with LA severity in acute stroke patients. Methods: We analyzed 271 patients with acute ischemic or hemorrhagic stroke from a hospital registry. We collected clinical and socioeconomic data prospectively with a standardized questionnaire during acute stroke hospitalization.
Source: Journal of Stroke and Cerebrovascular Diseases - April 24, 2019 Category: Neurology Authors: Kishore Vedala, Arun K. Nagabandi, Stephen Looney, Askiel Bruno Source Type: research
Urban Versus Rural Egypt: Stroke Risk Factors and Clinical Profile: Cross-Sectional Observational Study
Background: Egypt is a densely populated country with living habits and health care services that differ from urban to rural regions. We aimed to study how characteristics of stroke vary among these regions. Methods: This is a cross-sectional observational study of ischemic stroke, thus hemorrhagic and venous strokes were excluded. A total of 1475 ischemic stroke patients were recruited for analysis from a tertiary hospital in Cairo representing urban area and from a secondary care hospital in Suhag representing rural region.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2019 Category: Neurology Authors: Nevine M. El Nahas, Hossam M. Shokri, Tamer M. Roushdy, Hany M. Aref, Salma M. Hamed, Ali S. Shalash, Mohamed I. Abdelrahem, Noha L. Dawood, Eman M. Abushady, Shady S. Georgy, Amr S. Zaki, Rady Y. Bedros Source Type: research
The Association Between Stroke Mortality and Time of Admission and Participation in a Telestroke Network
Objectives: Acute ischemic stroke is one of the leading causes of death. Patient outcomes, such as in-patient mortality, may be impacted by the time of arrival to the hospital. Telestroke networks have been found to be effective and safe at treating acute ischemic strokes. This paper investigated the association between mortality and time of arrival and hospital's participation in a telestroke network. Methods: Data were collected on ischemic stroke patients who arrived at 15 nonteaching hospitals in Georgia's Paul Coverdell Acute stroke registry from 2009 to 2016.
Source: Journal of Stroke and Cerebrovascular Diseases - November 25, 2019 Category: Neurology Authors: Brian Witrick, Donglan Zhang, Jeffrey A. Switzer, David C. Hess, Lu Shi Source Type: research
