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Total 155 results found since Jan 2013.

Ramipril improves walking times and quality of life in patients with stable intermittent claudication
Commentary on: Ahimastos AA, Walker PJ, Askew C, et al.. Effect of ramipril on walking times and quality of life among patients with peripheral artery disease and intermittent claudication: a randomized controlled trial. JAMA 2013;309:453–60. Context Intermittent claudication (IC) is a common condition that may be associated with significant disability and reduction in quality of life. Pharmacological options for the treatment of the symptoms of this condition are very limited. Naftidrofuryl oxalate is recommended in the National Institute for Health and Care Excellence (NICE) guidelines,1 and while this has been sho...
Source: Evidence-Based Medicine - January 22, 2014 Category: Internal Medicine Authors: Brittenden, J. Tags: Health policy, Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Stroke, Hypertension, Health service research Therapeutics Source Type: research

Editorial Statins for millions more?
Last week, the National Institute for Health and Care Excellence (NICE) in the UK unveiled draft guidance on cardiovascular risk assessment and, in particular, on lipid modification for the primary and secondary prevention of cardiovascular disease. In an update to the existing guideline, the new proposal is that the threshold be halved for prescribing statins to prevent cardiovascular disease, which includes coronary heart disease and stroke.
Source: LANCET - February 21, 2014 Category: Journals (General) Authors: The Lancet Tags: Editorial Source Type: research

Statins and cardiovascular disease.
Authors: Abstract Essential facts Heart disease, stroke and peripheral arterial disease, known collectively as cardiovascular disease (CVD), cause one in three of all deaths in the UK. High levels of low-density lipoprotein (LDL) cholesterol can lead to hardening of the arteries, a risk factor for CVD. Statins are a group of drugs that act on the liver to lower LDL cholesterol rates in the blood. As many as seven million people in the UK currently take statins, at a cost of £285 million a year, according to the National Institute for Health and Care Excellence (NICE). PMID: 24641035 [PubMed - in process]
Source: Nursing Standard - March 19, 2014 Category: Nursing Tags: Nurs Stand Source Type: research

Resistant hypertension: resistance to treatment or resistance to taking treatment?
The treatment of hypertension has been a therapeutic success. A generation or more of effective drugs deserves considerable credit for their contribution to the substantial decline in age-related incidence of stroke, ischaemic heart disease and heart failure. And because almost all the drugs are long-since off patent, the cost of success comes cheaply. Indeed, National Institute of Health and Care Excellence (NICE) has branded treatment of hypertension as not only cost effective but cost saving.1 Yet not all patients achieve their blood pressure target and are labelled as ‘resistant hypertension’. A contentious...
Source: Heart - May 8, 2014 Category: Cardiology Authors: Brown, M. J. Tags: Drugs: cardiovascular system, Hypertension, Interventional cardiology, Epidemiology Editorials Source Type: research

NICE: 'Obese should be prescribed slimming clubs'
“GPs told to prescribe £100 slimming courses for millions of obese patients,” the Daily Mail reports. The news is based on new guidelines from the National Institute for Health and Care Excellence (NICE) that aim to encourage sustainable weight loss in the obese; “lose a little, and keep it off”. The guidance is mainly aimed at commissioners (who plan and agree which services will be provided in the NHS and monitor them), health professionals and groups who provide lifestyle weight management programmes. The recommendations may also be of interest to members of the public, including people who are overweight or o...
Source: NHS News Feed - May 28, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Food/diet Obesity QA articles Source Type: news

NICE faces increasing row over statins
Doctors demand withdrawal of new NICE guidance that goes ‘a step too far’Related items from OnMedicaBMJ withdraw statements about statin safetyOverview of statinsStatins should be offered to people more widelyStatin use after stroke not linked to bleedsDrugs regulators “put profits before patients”
Source: OnMedica Latest News - June 11, 2014 Category: UK Health Source Type: news

GPs to review aspirin use in atrial fibrillation patients
NICE calls for increased uptake of anticoagulantsRelated items from OnMedicaAlteplase use linked to reduction in disability after strokeGPs should screen over 65s for atrial fibrillationAtrial fibrillation raises risk of cognitive problems Statin use after stroke not linked to bleedsNew guidance to prevent strokes
Source: OnMedica Latest News - June 19, 2014 Category: UK Health Source Type: news

Question 1: Is ultrasound scanning as sensitive as CT in detecting skull fractures in children presenting following head injury?
Scenario An 11-month-old child is brought to the emergency department following a witnessed fall from a dining room chair. There was no loss of consciousness and only a single episode of vomiting immediately following the fall. Neurological examination is normal, however, there is a 5 cm bruised boggy swelling in the left parietal region and you suspect there may be a skull fracture. The child meets the criteria for neuroimaging with CT scanning according to NICE guidance.1 The parents express anxiety about radiation exposure (a young relative is currently being treated for leukaemia), in addition to concerns about th...
Source: Archives of Disease in Childhood - September 11, 2014 Category: Pediatrics Authors: Burke, K., Christian, W. Tags: ADC Archimedes, Oncology, Neurological injury, Stroke, Radiology, Other anaesthesia, Clinical diagnostic tests, Radiology (diagnostics), Trauma, Injury Source Type: research

Watch less TV to prevent obesity, says NICE
“Take TV-free days to combat obesity, health experts urge,” The Guardian reports. This is one of a range of new recommendations from National Institute of Health and Care Excellence (NICE) draft guidelines that are designed to help adults and children maintain a healthy weight.Although the headlines have largely focused on TV (as well as other types of screen time, such as smartphones), the recommendations cover a range of health-related behaviours, such as walking to work and avoiding fizzy drinks.This draft guidance is mainly aimed at people in organisations who set up, pay for, or put into practice programmes that ...
Source: NHS News Feed - September 23, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Food/diet Obesity Source Type: news

NICE recommends more INR self-monitoring
Quicker dose adjustment will result in fewer major bleeds, MIs and strokes, says guidanceRelated items from OnMedicaHuge benefits to new anti-clotting drugAspirin as effective as warfarin for heart patientsDaily aspirin use linked to major bleedingStatin use after stroke not linked to bleedsSelf-monitoring cuts warfarin clot risk
Source: OnMedica Latest News - September 25, 2014 Category: UK Health Source Type: news

Alteplase for the Treatment of Acute Ischaemic Stroke: A NICE Single Technology Appraisal; an Evidence Review Group Perspective
Abstract The National Institute for Health and Care Excellence (NICE) invited Boehringer Ingelheim GmbH, the manufacturer of alteplase, to submit evidence for the clinical and cost-effectiveness of alteplase for the prevention of strokes within a 0–4.5 h window. The comparator was standard medical and supportive management that does not include alteplase. This paper provides a description of the company submission, the Evidence Review Group (ERG) review and NICE's subsequent decisions. Clinical effectiveness evidence for alteplase was derived from 5 trials. For the 3–4.5 h treatment window, alteplase did not...
Source: PharmacoEconomics - November 26, 2014 Category: Health Management Source Type: research

Offer weight loss surgery to obese people with diabetes
A quarter of the UK population is now obese, fuelling a rise in cases of type 2 diabetes, as well as heart disease, fatty liver disease and cancer. One in 20 people in the UK has type 2 diabetes, a progressive disease that causes heart disease, stroke, blindness, kidney failure and limb amputations. Updated NICE guidance focuses on identifying, assessing and treating people who are already obese.
Source: NHS Networks - December 1, 2014 Category: UK Health Authors: Maria Axford Source Type: news

7 Ways to Permanently Banish Belly Fat
Sixty-nine percent of Americans adults are overweight, and over 35 percent are obese. Obesity increases your risk for numerous conditions including heart disease, stroke, Type 2 diabetes, high blood pressure, and cancer. Sadly, about 3.4 million adults die each year from being overweight or obese. Globally obesity now kills about the same as tobacco and all wars, terrorism and violence. Nearly all people who are overweight already have "pre-diabetes" and have significant risks of disease and death. They just don't know it. When you begin to put on weight, especially lethal belly fat, your biology shifts out of balance, v...
Source: Healthy Living - The Huffington Post - February 27, 2015 Category: Consumer Health News Source Type: news

Nurses vote to accept a 1% pay rise
‘Fight for fair pay not over’ says RCNRelated items from OnMedicaTroubled Barts Health NHS Trust loses senior staffMinimum staff ratios needed in A&E, NICE recommendsMPs called to sign safe staffing manifestoWeekend nursing ratios hit stroke mortalityPay blow 'will hit nurse recruitment and retention'
Source: OnMedica Latest News - March 5, 2015 Category: UK Health Source Type: news

7 Steps To Finding Your True Purpose
SPECIAL FROM Grandparents.com With average life expectancy now approaching 80, Americans can look forward to spending almost two decades enjoying retirement. That free time can seem heavenly at first—until the days stretch on. "[After] the honeymoon stage comes the disenchantment stage," says Dr. Sara Yogev, psychologist and author of "A Couple's Guide to Happy Retirement." "People feel like everything is purposeless. They can get depressed, and we would like to avoid that stage." Discovering your purpose—your driving force—is a proven way of escaping that emptiness. "From what we know from research, those that hav...
Source: Healthy Living - The Huffington Post - April 16, 2015 Category: Consumer Health News Source Type: news