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Elevated ischemic stroke risk among women living with HIV infection
Conclusion: The increased risk of ischemic stroke among WLWH compared with HIV-uninfected women persisted after adjusting for both traditional and sex-specific stroke risk factors. Further investigation into the mechanisms of elevated stroke risk among WLWH, including immunologic factors, will be key for developing targeted preventive strategies for this at-risk population.
Source: AIDS - December 1, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Stroke incidence is highest in women and non-Hispanic blacks living with HIV in the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort
Conclusion: Women and non-Hispanic Blacks living with HIV had the highest incidence rates of stroke/TIA. A concerted effort must be made to include PLWH from these at-risk groups in observational and interventional studies aimed at understanding stroke mechanisms and reducing stroke risk in HIV infection. Strategies to modify stroke risk in PLWH should employ a multipronged approach targeting vascular risk factors and engaging and retaining patients in HIV care.
Source: AIDS - May 11, 2018 Category: Infectious Diseases Tags: Clinical Science Source Type: research

History of AIDS in HIV-Infected Patients Is Associated With Higher In-Hospital Mortality Following Admission for Acute Myocardial Infarction and Stroke
Conclusions. Patients with a history of AIDS were significantly more likely than uninfected patients to die during hospitalization after admission for AMI or stroke. This disparity was not observed when infected patients without a history of AIDS were compared to uninfected patients, implying that preserving immune function may improve cardiovascular outcomes in HIV-infected persons.
Source: The Journal of Infectious Diseases - May 23, 2016 Category: Infectious Diseases Authors: Okeke, N. L., Hicks, C. B., McKellar, M. S., Fowler, V. G., Federspiel, J. J. Tags: HIV/AIDS Source Type: research

Effect of CD4+ cell count and viral suppression on risk of ischemic stroke in HIV infection
Conclusion:Achieving viral suppression may reduce ischemic stroke risk, including risk of atherosclerotic strokes, in HIV-infected individuals.
Source: AIDS - October 31, 2014 Category: Infectious Diseases Tags: Clinical Science: Concise Communications Source Type: research

Risk factors and outcomes of HIV-associated stroke in Zambia
Objective: To compare risk factors and clinical outcomes between people with HIV (PWH) and HIV-uninfected (HIV−) adults with stroke hospitalized in Zambia. Methods: We retrospectively reviewed charts of all adults admitted to the University Teaching Hospital in Lusaka, Zambia with a clinical diagnosis of stroke between October 2018 and March 2019. Standardized data collection instruments were used to collect demographic, clinical, laboratory and imaging results. Comparison between individuals with and without HIV infection was made using t tests for continuous parametric variables, Wilcoxon rank-sum tests for ...
Source: AIDS - October 12, 2021 Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research

Nigeria: HIV Top Risk Factor for Stroke in Young Adults - Study
[Leadership] HIV infection is the leading risk factor for stroke in young African adults, a new study by the University of Liverpool's Institute of Infection and Global Health has found.
Source: AllAfrica News: HIV-Aids and STDs - December 23, 2015 Category: Infectious Diseases Source Type: news

Nigeria: More Nigerians Will Die of Cancer, Stroke Than Malaria, HIV By 2023
[This Day] Abuja -A new report entitled: 'Dissemination of Research Findings Programme Agenda and Analysis of Non-Communicable Diseases Prevention Policies in Africa' inaugurated by African health scientists said deaths from non-communicable diseases, particularly, cancer, stroke, diabetes, hypertension among others will increase in Nigeria in the next seven years.
Source: AllAfrica News: HIV-Aids and STDs - September 28, 2016 Category: Infectious Diseases Source Type: news

HIV infection, hypercoagulability and ischaemic stroke in adults at the University Teaching Hospital in Zambia: a case control study
In Zambia, 14.2% of adults have HIV/AIDS. There has been a substantial and significant increase in patients hospitalized for ischaemic stroke with co-existing HIV infection. However, little is known about the ...
Source: BMC Infectious Diseases - May 18, 2017 Category: Infectious Diseases Authors: Stanley Zimba, Patrice Mukomena Ntanda, Shabir Lakhi and Masharip Atadzhanov Source Type: research

Cardiovascular outcomes among HIV-infected veterans receiving atazanavir
Conclusion: Among treatment-naive HIV-infected patients in the Veterans Health Administration initiating ATV-containing regimens, risk of both MI and stroke were significantly lower than in those initiating regimens containing other protease inhibitors, NNRTIs, or INSTIs.
Source: AIDS - September 15, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Death after diagnosis of noncommunicable disease comorbid conditions, stratified by injection drug use
Conclusion: Persons with a history of injection drug use and non-IDU had strikingly similar risk and hazard of mortality after several major NCD diagnoses. Mortality after cancer diagnosis in this cohort was higher for persons with a history of IDU than those without; this may be because of being diagnosed with a different mix of specific sites and stages of cancers.
Source: AIDS - December 20, 2018 Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research

Association of injection drug use with incidence of HIV-associated non-AIDS-related morbidity by age, 1995–2014
Conclusion: Not all HANA comorbidities occur with higher incidence in PWID compared with non-IDU. However, higher incidence of ESRD and ESLD among PWIDs highlights the importance of recognition and management of markers of these comorbidities in early stages among PWID.
Source: AIDS - May 13, 2016 Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research

Ischemic Stroke in HIV-Infected Patients Ischemic Stroke in HIV-Infected Patients
Learn about the factors that may contribute to the risk of ischemic cerebral events among HIV-infected patients.HIV Medicine
Source: Medscape Hiv-Aids Headlines - March 13, 2017 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

HIV and Cardiovascular Disease: Update on Clinical Events, Special Populations, and Novel Biomarkers
The objective of this review is to provide an update on the link between HIV infection and cardiovascular disease (CVD). We will focus our review mainly on literature describing clinical CVD events and understudied topics of importance.Recent FindingsHeart failure, peripheral artery disease, and stroke are CVD modalities deserving more attention in the context of HIV infection in the highly active antiretroviral therapy era. Incidence data on clinical CVD from HIV populations in low- and middle-income countries are limited. Multisubstance use is common in HIV, but understudied as a moderator or mediator of the association ...
Source: Current HIV/AIDS Reports - May 11, 2018 Category: Infectious Diseases Source Type: research

Role of pre-stroke immunity in ischemic stroke mechanism among patients with  HIV
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Source: AIDS Care - August 21, 2018 Category: Infectious Diseases Authors: Jose Gutierrez Camilla Ingrid Hatleberg Henry Evans Michael T. Yin Source Type: research

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