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Herpes Zoster and the Risk for Stroke in Patients with Autoimmune Diseases
Conclusion: In patients with autoimmune diseases, incident HZ was associated with up to a two‐fold increased risk for stroke in the subsequent few months. These data provide urgency for developing strategies to reduce the risk of VZV. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - September 1, 2016 Category: Rheumatology Authors: L.H. Calabrese, F. Xie, H. Yun, K. Winthrop, J.W. Baddley, C. Calabrese, J.R. Curtis Tags: Full Length Source Type: research

In Context News in brief
Herpes zoster infection can transiently increase the risk of stroke, according to the results of a recent case series analysis. 42954 patients aged at least 65 years with a zoster diagnosis and who had had an ischaemic stroke were identified from Medicare databases in the USA over a 5 year period. By calculating age-adjusted incidence ratios for predefined periods of up to 12 months after zoster diagnosis, the investigators showed a 2·4 times increase in the risk of ischaemic stroke (2·37, 95% CI 2·17-2·59) in the first week after diagnosis that decreased gradually over 6 months.
Source: Lancet Neurology - January 12, 2016 Category: Neurology Tags: In Context Source Type: research

Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States
Conclusions Stroke and MI rates are transiently increased after exposure to herpes zoster. We found no evidence for a role of zoster vaccination in these associations. These findings enhance our understanding of the temporality and magnitude of the association between zoster and acute cardiovascular events.
Source: PLoS Medicine - December 15, 2015 Category: Internal Medicine Authors: Caroline Minassian et al. Source Type: research