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The Great Contrast Shortage of 2022 —Lessons learnt in Australia
ConclusionOur findings demonstrate that the IBCM shortage crisis had a very significant impact on the delivery of healthcare. While V/Q scans could (partially) substitute for CTPA studies in suspected pulmonary emboli, there appeared to be no valid alternative for CTNA studies in stroke calls. The unexpected and critical shortage of IBCM forced healthcare professionals to conserve resources, prioritise indications, triage patients based on risk, explore alternate imaging strategies and prepare for similar events recurring in the future.
Source: Journal of Medical Imaging and Radiation Oncology - May 18, 2023 Category: Radiology Authors: Giles Kisby, James H Seow, Greg Schie, Constantine C Phatouros, Kay ‐Vin Lam, Tracey Muir, Sally Burrows, Paul M Parizel Tags: Medical Imaging —Original Article Source Type: research

SARS-CoV-2 infection and SLE: endothelial dysfunction, atherosclerosis, and thrombosis
We present systemic lupus erythematosus (SLE) as a model rheumatic disease with endothelial dysfunction and discuss its mechanisms, factors that influence the early onset and rapid progression of atherosclerosis, and the increased risk of thromboembolic events. We focus on established methods to improve endothelium function, including statins, antiplatelet, and antithrombotic therapy. Hypercoagulable and hypofibrinolitic states and a hyperinflammatory response characterize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Several pathogenic mechanisms are typical for an acute phase of Covid-19 post-Co...
Source: Atherosclerosis - January 9, 2023 Category: Cardiology Authors: Wojciech P łazak Leszek Drabik Source Type: research

Evaluation of Cerebrovascular Reactivity and Vessel-Wall Imaging in Patients With Prior COVID-19: A Prospective Case-Control MRI Study
Conclusion: SARS-CoV2 infection is associated with chronic CVR impairment. The mechanistic basis is unknown from this study. Clinical Impact: Future studies are needed to determine the clinical implications arising from SARS-CoV2-associated CVR impairment.PMID:36000667 | DOI:10.2214/AJR.22.28267
Source: Atherosclerosis - August 24, 2022 Category: Cardiology Authors: Andrew L Callen Jody Tanabe Ashesh A Thaker Rebecca Pollard Brian Sauer William Jones Jack Pattee Brandon Steach Vincent Timpone Source Type: research

Mechanical thrombectomy in COVID-19-associated ischaemic stroke: patient characteristics and outcomes in a single-centre study
CONCLUSION: In AIS patients treated with MT, concomitant SARS-CoV2 infection did not affect the outcome. Our observations need to be confirmed in larger, and preferably multicentre, studies.PMID:35315928 | DOI:10.5603/PJNNS.a2022.0026
Source: Neurologia i Neurochirurgia Polska - March 22, 2022 Category: Neurology Authors: Katarzyna Sawczy ńska Pawe ł Wrona Tomasz K ęsek Marcin Wnuk Robert Chrzan Tomasz Homa Roman Pu łyk Jeremiasz Jagie łła Tadeusz Popiela Agnieszka S łowik Source Type: research

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