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Predicting the response to methylprednisolone pulses in patients with SARS-COV-2 infection
CONCLUSIONS: In patients with methylprednisolone pulses, the capacity of the predictive model for hospital discharge including variables collected at 5 days was (area under the curve) 0.816.PMID:35718548 | DOI:10.1016/j.medcli.2022.02.025
Source: Medicina Clinica - June 19, 2022 Category: General Medicine Authors: Antonio J Sarri á-Landete Jos é A Crespo-Matas Inmaculada Dom ínguez-Quesada Jes ús J Castellanos-Monedero Din és Marte-Acosta Ángel J Arias-Arias Source Type: research

Dual antiplatelet use in the management of COVID-19 associated acute ischemic stroke reocclusion
CONCLUSION: COVID-19 AIS may be associated with a hypercoagulable state which risks malignant reocclusion complicating MT. We found antithrombotic treatment periprocedural cangrelor with or without argatroban transitioned to oral aspirin with ticagrelor to be a viable method for management of these patients.PMID:35549746 | DOI:10.1177/15910199221097484
Source: Interventional Neuroradiology - May 13, 2022 Category: Radiology Authors: Joshua Feler Carlin Chuck Matthew Anderson Jonathan Poggi Joseph Sweeney Krisztina Moldovan Mahesh V Jayaraman Ryan McTaggart Radmehr Torabi Source Type: research

COVID-19 and supra-aortic trunks disease: review of literature about critical phase and sequelae
J Cardiovasc Surg (Torino). 2021 Sep 28. doi: 10.23736/S0021-9509.21.12021-X. Online ahead of print.ABSTRACTThe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 disease, a global pandemic. A strong association has been documented between COVID-19 and cardiovascular events, although the exact pathophysiological mechanism is still unclear. Carotid atherothrombosis and ischemic stroke represents one of the possible severe manifestations of COVID-19, as a leading cause of long-term disability and death. Different complex intertwined mechanisms seem to underlie the endothelitis which is the ...
Source: The Journal of Cardiovascular Surgery - September 28, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Renato Casana Maurizio Domanin Silvia Romagnoli Daniele Bissacco Chiara Malloggi Viviana Grassi Vincenzo Silani Gianfranco Parati Marc L Schermerhorn Santi Trimarchi Source Type: research

Cerebral Herniation Secondary to Stroke-associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
We present the case of a very rapid neurologic and radiographic decline of a patient with an acute ischemic stroke who developed rapid fulminant cerebral edema leading to herniation in the setting of hypercarbic respiratory failure attributed to SARS-CoV-2 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2020 Category: Neurology Authors: Katarina Dakay, Gurmeen Kaur, Stephan A. Mayer, Justin Santarelli, Chirag Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research