Filtered By:
Infectious Disease: Chagas Disease
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 91 results found since Jan 2013.
Anxiety, depression, and memory loss in Chagas disease: a puzzle far beyond neuroinflammation to be unpicked and solved
Mem Inst Oswaldo Cruz. 2023 Apr 3;118:e220287. doi: 10.1590/0074-02760220287. eCollection 2023.ABSTRACTMental disorders such as anxiety, depression, and memory loss have been described in patients with chronic Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. Social, psychological, and biological stressors may take part in these processes. There is a consensus on the recognition of an acute nervous form of CD. In chronic CD patients, a neurological form is associated with immunosuppression and neurobehavioural changes as sequelae of stroke. The chronic nervous form of CD ...
Source: Memorias do Instituto Oswaldo Cruz - April 5, 2023 Category: Infectious Diseases Authors: Joseli Lannes-Vieira Glaucia Vilar-Pereira Leda Casta ño Barrios Andrea Alice Silva Source Type: research
Association of left ventricular abnormalities with incident cerebrovascular events and sources of thromboembolism in patients with chronic Chagas cardiomyopathy
Although Chagas cardiomyopathy is related to thromboembolic stroke, data on risk factors for cerebrovascular events in Chagas disease is limited. Thus, we assessed the relationship between left ventricular (LV...
Source: Journal of Cardiovascular Magnetic Resonance - November 3, 2022 Category: Radiology Authors: Henrique Turin Moreira, Gustavo Jardim Volpe, Gustavo Marques Mesquita, Maria Fernanda Braggion-Santos, Antonio Pazin-Filho, Jos é Antonio Marin-Neto and André Schmidt Tags: Research Source Type: research
IL-1 β is not critical to chronic heart dysfunction in mice with Chagas disease
In conclusion, the absence of functional IL-1β/IL-1R signaling did not prevent or reverse the decrease of SV or the incidence of cardiac arrhythmias induced by chronic T. cruzi infection, implying this is not a critical mechanism in generating or maintaining CCC. Since similar cardiac abnormalities were previously credited to IL-1β signaling, ruling out this mechanism is important to discourage further attempts of IL-1β blockade as a therapeutical measure.
Source: Frontiers in Immunology - October 14, 2022 Category: Allergy & Immunology Source Type: research
Platelets, Macrophages, and Thromboinflammation in Chagas Disease
J Inflamm Res. 2022 Oct 4;15:5689-5706. doi: 10.2147/JIR.S380896. eCollection 2022.ABSTRACTChagas disease (CD) is a major health problem in the Americas and an emerging health problem in Europe and other nonendemic countries. Several studies have documented persistence of the protozoan parasite Trypanosoma cruzi, and oxidative and inflammatory stress are major pathogenic factor. Mural and cardiac thrombi, cardiac arrhythmias, and cardiomyopathy are major clinical features of CD. During T. cruzi infection, parasite-released factors induce endothelial dysfunction along with platelet (PLT) and immune-cell activation. PLTs hav...
Source: Cell Research - October 11, 2022 Category: Cytology Authors: Subhadip Choudhuri Nisha J Garg Source Type: research
