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Stroke in Chagas disease: from pathophysiology to clinical practice
Rev Soc Bras Med Trop. 2022 Jun 6;55:e0575. doi: 10.1590/0037-8682-0575-2021. eCollection 2022.ABSTRACTDespite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern. The disease affects approximately 6 million people, of whom 20-40% will develop cardiomyopathy over the years after the initial Trypanosoma cruzi infection. Chagas cardiomyopathy is the most serious and frequent manifestation of Chagas disease. Clinical manifestations vary widely according to the severity of myocardial dysfunction, ranging from asymptomatic ...
Source: Atherosclerosis - June 8, 2022 Category: Cardiology Authors: Tha ís Aparecida Reis Lage Julia Teixeira Tupinamb ás Lucas Bretas de P ádua Matheus de Oliveira Ferreira Amanda Cambraia Ferreira Antonio Lucio Teixeira Maria Carmo Pereira Nunes Source Type: research

Ischemic stroke and infectious diseases in low-income and middle-income countries
Purpose of review To address the important relationships between stroke and infection, focusing on the most frequent infections found in low-income and middle-income countries. Recent findings Stroke is one of the leading causes of mortality and disability worldwide, with a great proportion of the stroke burden occurring in low-income and middle-income countries. Infectious diseases are still a great health problem in developing countries and it is possible that the proportion of infection-related strokes is greater in these nations. Infectious diseases and stroke have a bidirectional relationship. Common infections m...
Source: Current Opinion in Neurology - January 13, 2019 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Didier Leys Source Type: research

Prevalence and Risk Factors of Embolic Cerebrovascular Events Associated With Chagas Heart Disease
Conclusions In a selected population referred to a tertiary center for Chagas disease that included patients with different severities of cardiac involvement, the prevalence of ICE was 20%. The presence of apical aneurysm and intracavitary thrombus were independently associated with ICE, after adjustment for other risk factors for stroke.
Source: Global Heart - September 28, 2015 Category: Cardiology Source Type: research