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Pentraxin 3 in Cardiovascular Disease
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1 1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy 2Humanitas Clinical and Research Center-IRCCS, Milan, Italy 3Humanitas University, Milan, Italy 4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research

Isolation of Antimicrobial Compounds From Cnestis ferruginea Vahl ex. DC (Connaraceae) Leaves Through Bioassay-Guided Fractionation
Conclusion In conclusion, aqueous extracts of C. ferruginea leaves showed antimicrobial activity due to the presence of hydroquinone and caffeic acid methyl ester. This supports its traditional use for infections and confirmed that the active molecules are water-soluble. Author Contributions KK, SP, LVP, and WL conceived and designed the experiments. SP, KK, M-RY, and J-GL performed the experiments. SP, LVP, WL, M-RY, J-GL, and Z-HJ analyzed the data. WL and Z-HJ contributed reagents, materials, and analysis tools. KK, SP, WL, M-RY, Z-HJ, and LVP contributed to the writing of the manuscript. All authors contributed to m...
Source: Frontiers in Microbiology - April 10, 2019 Category: Microbiology Source Type: research

Here Are the Real Victims of Pakistan’s War on the Taliban
An elderly displaced man carries a sack of rations on his shoulder. The Pakistan Army has distributed 30,000 ration packs of 110 kg each. Credit: Ashfaq Yusufzai/IPSBy Ashfaq YusufzaiPESHAWAR, Pakistan, Jul 1 2014 (IPS) Three days ago, Rameela Bibi was the mother of a month-old baby boy. He died in her arms on Jun. 28, of a chest infection that he contracted when the family fled their home in Pakistan’s North Waziristan Agency, where a full-scale military offensive against the Taliban has forced nearly half a million people to flee. Weeping uncontrollable, Bibi struggles to recount her story. “My son was born on Jul. 2...
Source: IPS Inter Press Service - Health - July 1, 2014 Category: Global & Universal Authors: Ashfaq Yusufzai Tags: Aid Armed Conflicts Asia-Pacific Development & Aid Economy & Trade Editors' Choice Environment Featured Food & Agriculture Gender Headlines Health Human Rights Humanitarian Emergencies Migration & Refugees Population Povert Source Type: news

Australia faces increased risk of disease from climate change, reports find
A number of recent studies have shown a clear connection between a warming planet and increased health risksAustralia has been warned of the rising threat of dengue fever and heat stroke deaths in the wake of a study that found climate change is aiding the spread of infectious diseases around the world. The report, part-funded by the US National Science Foundation and published in Science, found that climate change is already abetting diseases in wildlife and agriculture, with humans at heightened risk from dengue fever, malaria and cholera. Wealthy countries will do much better at predicting and tackling new disease threa...
Source: Guardian Unlimited Science - August 2, 2013 Category: Science Authors: Oliver Milman Tags: theguardian.com News Climate change Environment Australia Source Type: news