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Comprehensive evaluation of the mechanism of Gastrodia elata Blume in ameliorating cerebral ischemia –reperfusion injury based on integrating fecal metabonomics and 16S rDNA sequencing
Gastrodia elata Blume was used to treat stroke and headaches caused by “Feng” for thousands of years. The present study has shown a significant effect of G. elata Blume in improving cerebral ischemia–reperfusion injury (CIRI). However, the mechanism of G. elata Blume in improving CIRI by regulating the intestinal flora has not been reported until now. This research aimed to comprehensively evaluate the mechanism of G. elata Blume in CIRI based on fecal metabolomics and 16S rDNA sequencing. The rat model with CIRI was created based on the Zea Longa method. Enzyme-linked immunosorbent assay (ELISA) was used to monitor ...
Source: Frontiers in cellular and infection microbiology - October 27, 2022 Category: Microbiology Source Type: research

Gut Dysbiosis Is Associated With the Severity of Cryptogenic Stroke and Enhanced Systemic Inflammatory Response
In conclusion, gut dysbiosis in CS patients was associated with the severity of CS and the systemic inflammation. Maintaining the intestinal homeostasis may be a potential strategy for the treatment of CS.
Source: Frontiers in Immunology - May 6, 2022 Category: Allergy & Immunology Source Type: research

Mortality and morbidity from infectious and non-communicable diseases in Greece during Axis/Nazi military occupation (1941-1944)
In conclusion, we found that the Axis/Nazi military occupation of Greece had considerable health effects on infectious diseases and hemorrhagic stroke mortality. Deaths ostensibly due to infectious diseases (e.g. tuberculosis or malaria), were expedited by the hunger famine of the period under investigation. With regard to the elevated mortality due to hemorrhagic stroke, we believe that the stressful events of occupation and famine have triggered increased psychosocial stress which in turn may have increased the risk of hemorrhagic stroke mortality during the period of Axis/Nazi occupation of Greece.PMID:35350253 | PMC:PM...
Source: Infezioni in Medicina - March 30, 2022 Category: Infectious Diseases Authors: Georgios Rachiotis Dimitrios Papagiannis Theodoros Dardavesis Panagiotis Behrakis Source Type: research

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