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Probiotics improve gut microbiota dysbiosis in obese mice fed a high-fat or high-sucrose diet
The prevalence of obesity has been dramatically increasing globally over decades [1]. Obesity is caused by a complex interaction of genetic and environmental factors, and is also suggested to be the result of a long-term imbalance between energy intake and expenditure [2]. Calorie-rich foods that are high in fat or carbohydrates combining with sedentary lifestyles are the most common factors underlying the global obesity epidemic [3]. High-fat diets (HFD) increase adipose tissue and induce metabolic and cardiovascular disorders (such as atherosclerosis, type 2 diabetes, stroke, and hypertension [4, 5]), especially in those...
Source: Nutrition - October 10, 2018 Category: Nutrition Authors: Cheng Kong, Renyuan Gao, Xuebing Yan, Linsheng Huang, Huanlong Qin Source Type: research

System biology approach intersecting diet and cell metabolism with pathogenesis of brain disorders
Publication date: Available online 27 July 2018Source: Progress in NeurobiologyAuthor(s): Fernando Gomez-Pinilla, Xia YangABSTRACTThe surge in meals high in calories has prompted an epidemic of metabolic disorders around the world such that the elevated incidence of obese and diabetic individuals is alarming. New research indicates that metabolic disorders pose a risk for neurological and psychiatric conditions including stroke, Alzheimer’s disease, Huntington’s disease, and depression, all of which have a metabolic component. These relationships are rooted to a dysfunctional interaction between molecular processes tha...
Source: Progress in Neurobiology - July 28, 2018 Category: Neuroscience Source Type: research

Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India
Conclusion: Greenness, ISA, and NTL were associated with increased SBP, DBP, and cPP, and with reduced FMD, suggesting a possible additional EVA pathway for the relationship between urbanization and increased CVD prevalence in urban India. https://doi.org/10.1289/EHP541 Received: 20 May 2016 Revised: 03 January 2017 Accepted: 23 January 2017 Published: 02 August 2017 Address correspondence to K.J. Lane, Yale School of Forestry and Environmental Studies, 195 Prospect Street, New Haven, CT 06511 USA. Telephone: (781) 696-4537; Email: kevin.lane@yale.edu Supplemental Material is available online (https://doi.org/10.1289...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

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