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Antibodies to Human Herpesviruses and Rate of Incident Cardiovascular Events and All-Cause Mortality in the UK Biobank Infectious Disease Pilot Study
CONCLUSIONS: In this mostly White UK Biobank subset, neither HHV seropositivity nor titers were associated with stroke/MI or all-cause mortality.PMID:35873304 | PMC:PMC9301583 | DOI:10.1093/ofid/ofac294
Source: Herpes - July 25, 2022 Category: Infectious Diseases Authors: Petrina Chu Sharon Louise Cadogan Charlotte Warren-Gash Source Type: research

Lack of Association between Seropositivity of Vasculopathy-Related Viruses and Moyamoya Disease
CONCLUSIONS: Our cross-sectional study suggest that the investigated 11 viruses including HHV6 are unlikely to have an impact on MMD development.PMID:35500358 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106509
Source: Herpes - May 2, 2022 Category: Infectious Diseases Authors: Yasuhisa Nakamura Yohei Mineharu Takahiko Kamata Takeshi Funaki Susumu Miyamoto Akio Koizumi Kouji H Harada Source Type: research

Association of Cytomegalovirus Infection with Lenticulostriate Stroke After Mild Head Trauma in Young Children
In this study, we explored the association of a recent viral infection with the development of infantile lenticulostriate stroke with lenticulostriate calcification following mild head trauma in children. We examined the records for 49 children (<36 months old) diagnosed with infantile stroke following mild head trauma at the First Hospital of Jilin University between January 2007 and August 2019. The demographic characteristics, clinical manifestations, and laboratory and imaging results were collected and analyzed. Antibodies against Epstein-Barr virus, herpes simplex virus, and cytomegalovirus in the patient sera wer...
Source: Herpes - February 4, 2022 Category: Infectious Diseases Authors: Guangming Wang Jianmin Liang Cuijuan Xin Linyun Wang Xuemei Wu Source Type: research

Intracranial Large Artery Stenosis and Past Infectious Exposures: Results From the NOMAS Cohort
CONCLUSIONS: Chronic infectious exposures, specifically herpes simplex virus 2 and cytomegalovirus were associated with asymptomatic ILAS as seen on magnetic resonance angiogram imaging. This may represent an additional target of intervention in the ongoing effort to stem the substantial global burden of strokes related to ILAS.PMID:35105181 | DOI:10.1161/STROKEAHA.121.036793
Source: Herpes - February 2, 2022 Category: Infectious Diseases Authors: Amol Mehta Farid Khasiyev Clinton B Wright Tatjana Rundek Ralph L Sacco Mitchell S V Elkind Jose Gutierrez Source Type: research

Presence of asymptomatic cytomegalovirus and Epstein--Barr virus DNA in blood of persons with HIV starting antiretroviral therapy is associated with non-AIDS clinical events
Background: Even with antiretroviral therapy (ART), persons with HIV (PWH) experience increased morbidity and mortality. Cytomegalovirus (CMV) and Epstein--Barr virus (EBV) co-infections likely exacerbate inflammatory-related diseases. Objective: To determine if presence of detectable CMV or EBV DNA in peripheral blood mononuclear cells (PBMC) is associated with non-AIDS events among PWH receiving modern ART. Design: We performed a case--control study of PWH starting ART and HIV-suppressed at year 1 and thereafter, 140 cases who experienced non-AIDS events and 305 matched controls. Events included myocardial infarc...
Source: AIDS - April 9, 2020 Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research

Association of HIV and Opportunistic Infections With Incident Stroke: A Nationwide Population-Based Cohort Study in Taiwan
Conclusions: Patients with HIV had an increased risk of stroke, particularly those with cryptococcal meningitis, cytomegalovirus, or P. marneffei infection.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - January 12, 2017 Category: Infectious Diseases Tags: Epidemiology Source Type: research