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Analysis of risk factors for the efficacy of tirofiban in the treatment of acute ischemic stroke
CONCLUSION: The early curative effect of tirofiban in acute ischemic stroke patients with a heavy drinking history and elevated total cholesterol was poor. In patients with acute ischemic stroke, the higher the NIHSS score was within a certain range (8 < NIHSS ≤15 and the Org 10,172 Trial in the Treatment of Acute Stroke (TOAST) belongs to small-artery occlusion lacunar) at the initiation of treatment and the shorter the time from onset to treatment, the better the early curative effect was.PMID:36599001 | DOI:10.1080/01616412.2022.2164447
Source: Neurological Research - January 4, 2023 Category: Neurology Authors: Chong Liu Lu Yin Yinqin Hu Zhizhen Shi Qiaoyan Zhu Qian Xiao Guoyi Li Jiwei Cheng Yangbo Hou Source Type: research

The prognostic significance of the lipid profile after an ischemic stroke
CONCLUSIONS: The complete analysis of the lipid panel allows the determination of the prognosis of patients who suffered a stroke.PMID:34396927 | DOI:10.1080/01616412.2021.1967677
Source: Neurological Research - August 16, 2021 Category: Neurology Authors: Bruno Kusznir Vitturi Rubens Jos é Gagliardi Source Type: research

Factors associated with medication persistence among ischemic stroke patients: a systematic review.
Conclusions: Stroke patients' medication persistence decreases over time, and persistence on antiplatelets, anticoagulants, and statin was poor. Several factors were associated with medication persistence, and these factors should be considered in future secondary preventative strategies. PMID: 32321382 [PubMed - as supplied by publisher]
Source: Neurological Research - April 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Statin effects on post-stroke epilepsy and mortality - Taiwan population-based study.
Conclusion: Statins have a modest but non-significant effect in preventing post-apoplectic epilepsy in Taiwan. Statins decrease post-stroke mortality only in men. Further studies are needed to depict their exact roles in these issues. PMID: 32122287 [PubMed - as supplied by publisher]
Source: Neurological Research - March 4, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Low density lipoprotein cholesterol values and outcome of stroke patients: influence of previous aspirin therapy.
Conclusion: A worse outcome was seen in stroke patients with normal levels of LDLC, but this finding was restricted to patients not under previous aspirin therapy. PMID: 32024449 [PubMed - as supplied by publisher]
Source: Neurological Research - February 8, 2020 Category: Neurology Tags: Neurol Res Source Type: research

An analysis of the risk of perioperative ischemic stroke in patients undergoing non-cardiovascular and non-neurological surgeries.
Conclusions: History of stroke and smoking, renal insufficiency, and low HDL-C are independent risk factors for PIS. It is feasible to assess the risk of stroke in preoperative patients using PCE in clinical practice. PMID: 31903867 [PubMed - as supplied by publisher]
Source: Neurological Research - January 7, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Does the nutritional status of acute stroke patients affect the neurological status in the early post-stroke period?
Authors: Wierzbicki K, Horyniecki M, Mamak D, Szopa M, Buchała J, Stawarz G, Florek S, Adamczyk-Sowa M Abstract According to recent reports, malnutrition may be associated with a worse prognosis in stroke patients. The aim of this study was to determine the nutritional status of stroke patients and its impact on neurological and functional status of patients in the early post-stroke period. Our prospective study included a total of 128 patients admitted to the Stroke Unit. The assessment was made in the patients within the first week after the onset of stroke symptoms. Groups of patients with abnormal body mass in...
Source: Neurological Research - November 6, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Inpatient statin use and stroke recurrence in patients with or without diabetes mellitus.
Conclusion: Inpatient statin use was associated with lower stroke recurrence in non-diabetic patients after acute ischaemic stroke, but no definite association between inpatient statin use and stroke recurrence in patients with diabetes mellitus was found. PMID: 31328681 [PubMed - as supplied by publisher]
Source: Neurological Research - July 23, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Statin treatment before stroke reduces pro-inflammatory cytokine levels after stroke.
CONCLUSION: Stroke induces changes in the RhoA-ROCK pathway in T-cells. CRP and NIHSS score correlated positively in the study. Statins may have an anti-inflammatory effect as statin treatment before stroke reduces post-stroke pro-inflammatory levels. RhoA GTPase and its downstream effectors are possibly the key to improve statin treatment in stroke. PMID: 30574850 [PubMed - as supplied by publisher]
Source: Neurological Research - December 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Omega-3 fatty acid supplement reduces activation of NADPH oxidase in intracranial atherosclerosis stenosis.
Conclusions Long-term O3FA dietary supplementation prevents the development of intracranial atherosclerosis. This O3FA effect appears to be mediated by its attenuation of NOX subunit expression and NOX activity, therefore reducing ROS production. O3FA dietary supplement shows promising results in the prevention of ICAS. PMID: 29576013 [PubMed - as supplied by publisher]
Source: Neurological Research - March 27, 2018 Category: Neurology Tags: Neurol Res Source Type: research

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