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Preprocedural determination of an occlusion pathomechanism in endovascular treatment of acute stroke: a machine learning-based decision
Conclusions An ML-PM could accurately determine an occlusion pathomechanism with common preprocedural findings. A decision flowchart consisting of the four most influential findings was clinically applicable and superior to single common preprocedural findings for determining an occlusion pathomechanism.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Baek, J.-H., Kim, B. M., Kim, D. J., Heo, J. H., Nam, H. S., Kim, Y. D., Rho, M. H., Chung, P.-W., Won, Y. S., Chung, Y. Tags: Ischemic stroke Source Type: research

P146/118 NeVa ONE registry interim analysis: recanalization outcomes from a large, real-world patient cohort
ConclusionNeVa ONE Registry represents real-world data obtained from LVO AIS subjects treated with NeVa.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Bhogal, P., Diaz, J., Gallego, J. I., Dopico, M. S., Pfaff, J., Behme, D., Pero, G., Voormolen, M., John, S., Romero Florez, N. A., Celma, S. M., Waele, T. d., Francois, O., Cotroneo, E., Maleux, G. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O06/60 Diagnosis of intracranial atherosclerosis related large vessel occlusion before endovascular treatment
ConclusionA combination of clinical and radiological variables available before EVT can accurately predict the presence of an ICAD-LVO. The ICAD-Scale could be useful to perform a rapid assessment of underlying etiology and suggest specific pathophysiology-based measures (adjunctive pharmacological treatment, angioplasty and/or intracranial stenting).Disclosure of InterestDr Molina reported receiving personal fees from AstraZeneca for consultant services outside the submitted work. Dr Tomasello reported receiving personal fees from Anaconda Biomed, Balt, Medtronic, Perflow, and Stryker outside the submitted work. Dr Ribo r...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Rodrigo-Gisbert, M., Garcia-Tornel, A., Requena, M., Rubiera, M., Lascuevas, M. D. D., Olive, M., Pinana, C., Rizzo, F., Muchada, M., Rodriguez-Villatoro, N., Rodriguez-Luna, D., Juega, J., Pagola, J., Hernandez, D., Molina, C. A., Tomasello, A., Ribo, M. Tags: 2.2 ISCHEMIC - Imaging Source Type: research

E-086 The effect of covid-19 vaccines on stroke outcomes: a single-center study
ConclusionAlthough vaccination did not show any significant difference in stroke patient outcomes on follow-up, vaccines were associated with lower rates of morbidity and mortality at discharge among stroke patients during the pandemic.Abstract E-086 Table 1Comparison of outcomes between COVID-19-positive unvaccinated vs. fully vaccinated patients presenting with stroke.*Adjusted for hypertension, atrial fibrillation, PVD, admission NIHSS, ASPECTS, tandem occlusion, and thrombectomy Unvaccinated Vaccinated Effect Variable Unadjusted Value (95% CI ) Unadjusted p-value Adjusted Value (95% CI )* Adjusted p-value* Primary Out...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Amllay, A., Chen, C., Capone, S., Abbas, R., Sioutas, G., Munoz, A., Yudkoff, C., Carreras, A., Samabngi, A., Hunt, A., Jain, P., Stine, E., Sathe, A., Smit, R., Yazbeck, F., Tjoumakaris, S., Gooch, M., Herial, N., Rosenwasser, R., Zarzour Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

O-008 Endovascular thrombectomy outcomes stratified by hospital thrombectomy volume: a national inpatient sample study
ConclusionsPatients receiving EVT for AIS at HV centers were more likely to be discharged to home without assistance but demonstrated lower rates of in-hospital mortality when compared to IV and LV centers. Our findings support HV EVT performing centers render more favorable outcomes in this NIS analysis.Disclosures A. Brake: None. L. Fry: None. C. Heskett: None. G. LeBeau: None. C. Lei: None. A. Alkiswani: None. K. Le: None. F. De-Stefano: None. J. Peterson: None. K. Ebersole: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brake, A., Fry, L., Heskett, C., LeBeau, G., Lei, C., Alkiswani, A., Le, K., De-Stefano, F., Peterson, J., Ebersole, K. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

P-005 Predictors for large vessel recanalization before stroke thrombectomy
ConclusionsIVT at least 1.5 hours before angiography, site of vascular occlusion, atrial fibrillation, and hyperlipidemia are independent predictors for LVR. The 8-point Recan score proposed in this study may be a valuable tool for predicting LVR before EVT.Abstract P-005 Figure 1Disclosures H. Chen: None. M. Colasurdo: None. C. Schrier: None. M. Khalid: None. M. Khunte: None. T. Miller: None. J. Cherian: None. A. Malhotra: None. D. Gandhi: 1; C; National Institutes of Health, Focused Ultrasound Foundation, MicroVention, University of Calgary, University of Maryland Medical Center.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Chen, H., Colasurdo, M., Schrier, C., Khalid, M., Khunte, M., Miller, T., Cherian, J., Malhotra, A., Gandhi, D. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

E-245 Association of pre-treatment cerebral microbleeds with hemorrhagic transformation following successful endovascular recanalization in patients with acute ischemic stroke arising from large artery occlusion
ConclusionsThese findings suggest that the presence of CMBs is associated with HT and poor functional outcome following EVT and had no effect on mortality in patients with successful endovascular recanalization. However, CMBs do not show such a high impact on HT as other literature in our study. Therefore, it seems appropriate to consider CMB status in individual risk stratification of poor clinical outcome following recanalization by EVT with AIS. Future large and well-designed prospective studies are required to better characterize the underlying factors behind CMB-associated clinical deterioration.Abstract E-245 Figure ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Chung, S., Kim, J. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-248 Rescue intracranial stenting for failed posterior circulation thrombectomy: analysis from saint study
ConclusionIn patients with posterior circulation occlusion stokes who failed mechanical thrombectomy, our study suggests that RS has better outcomes with comparable safety profile. Randomized controlled studies are warranted for more concrete evidence.Abstract E-248 Table 1Baseline demographic, clinical and procedural characteristics among rescue stenting and failed reperfusion groups Rescue stentingN=84 Failed ReperfusionN=68 P value Age 63.6±12.6 69.7±13.5 0.005 Female 18 (21.4%) 35 (51.5%) <0.001 Ethnic BackgroundWhiteAAHispanicAsianOthers 33 (39.3%)20 (23.8%)22 (26.2%)4 (4.8%)5 (6%) 34 (50%)22 (32.4%)...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Mohammaden, M., Tarek, M., Haussen, D., Fifi, J., Matsoukas, S., Farooqui, M., Ortega-Gutierrez, S., Zevallos, C., Galecio-Castillo, M., Hassan, A., Tekle, W., Al-Bayati, A., Salem, M., Burkhardt, J., Pukenas, B., Cortez, G., Hanel, R., Aghaebrahim, A., S Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Intravenous thrombolysis before mechanical thrombectomy in patients with atrial fibrillation
The introduction into clinical practice of endovascular mechanical thrombectomy (MT) has brought better results in patients with ischemic stroke from large vessel occlusion (LVO) in the anterior circulation in whom therapy is started 4.5–5 hours after symptoms onset.1–3 Controversies exist about the usefulness of intravenous thrombolysis (IVT) before MT in patients with atrial fibrillation (AF). AF is the probable etiology in >25% of ischemic strokes, and >40% of patients with ischemic stroke from LVO in the anterior circulation have a clinical history of AF.4 5 AF is an independent predictor of poor func...
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Bozzani, A., Arici, V., Ragni, F., Sterpetti, A., Arbustini, E. Tags: Letter Source Type: research

Prediction of 90 day home time among patients with low baseline ASPECTS undergoing endovascular thrombectomy: results from Albertas Provincial Stroke Registry (QuICR)
Conclusions Patients with low ASPECTS who are selected for EVT using demographic and clinical profiles similar to higher ASPECTS patients achieved comparable outcomes.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Singh, N., Holodinsky, J. K., Kashani, N., McDonough, R. V., Bala, F., Horn, M., Stang, J., Demchuk, A. M., Hill, M. D., Almekhlafi, M. A. Tags: Vascular neurology Source Type: research

Obstructive sleep apnea confers lower mortality risk in acute ischemic stroke patients treated with endovascular thrombectomy: National Inpatient Sample analysis 2010-2018
Conclusions Our findings suggest that MT is a viable and safe treatment option for AIS patients with OSA.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Lapow, J. M., Dicpinigaitis, A. J., Pammal, R. S., Coghill, G. A., Rechester, O., Feldstein, E., Nuoman, R., Maselli, K., Kodi, S., Bauerschmidt, A., Rosenberg, J. B., Yaghi, S., Kaur, G., Kurian, C., Chong, J. Y., Mayer, S. A., Gandhi, C. D., Al-Mufti, F Tags: Vascular neurology Source Type: research

Intracranial non-occlusive intraluminal thrombus may indicate underlying etiology of large vessel occlusion in patients undergoing endovascular therapy
Conclusions The presence of iNOT may reflect an underlying ICAS related LVO in patients undergoing EVT.
Source: Journal of NeuroInterventional Surgery - September 14, 2022 Category: Neurosurgery Authors: Jang, S. H., Park, H., Yoo, J., Hong, J.-H., Lee, J. S., Lee, S.-J., Kim, Y.-W., Hong, J. M., Choi, J. W., Kang, D.-H., Kim, Y.-S., Hwang, Y.-H., Sohn, S.-I. Tags: Ischemic stroke Source Type: research

Bridging thrombolysis in atrial fibrillation stroke is associated with increased hemorrhagic complications without improved outcomes
Conclusion In this large thrombectomy registry, AF patients exposed to IVT before MT had increased hemorrhagic complications without improved functional outcomes, in contrast with non-AF patients. Prospective trials are warranted to assess whether AF patients represent a subgroup of LVO patients who may benefit from a direct to thrombectomy approach at thrombectomy capable centers.
Source: Journal of NeuroInterventional Surgery - September 14, 2022 Category: Neurosurgery Authors: Akbik, F., Alawieh, A., Dimisko, L., Howard, B. M., Cawley, C. M., Tong, F. C., Nahab, F., Samuels, O. B., Maier, I., Feng, W., Goyal, N., Starke, R. M., Rai, A., Fargen, K. M., Psychogios, M. N., Jabbour, P., De Leacy, R., Keyrouz, S. G., Dumont, T. M., Tags: Ischemic stroke Source Type: research

Predictors of futile recanalization after endovascular treatment in acute ischemic stroke: a meta-analysis
Conclusion This study identified female sex, comorbidities, admission systolic blood pressure, serum glucose, occlusion site, non-bridging therapy, and post-procedural complication as predictors of futile recanalization, and also confirmed previously reported factors. Further large-scale prospective studies are needed.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Deng, G., Xiao, J., Yu, H., Chen, M., Shang, K., Qin, C., Tian, D.-S. Tags: Ischemic stroke Source Type: research

O-016 Outcomes after endovascular mechanical thrombectomy for low national institutes of health stroke scale (NIHSS): a multicenter study
ConclusionsMT is an effective and safe treatment for appropriately selected ischemic stroke patients presenting with low NIHSS. Diabetes and prior stroke are predictors of functional dependence at 90 days, and prior stroke is also associated with mortality, suggesting that MT should be offered judiciously to patients with these risk factors. Our findings signal the need for a randomized trial comparing MT versus medical management for LVO patients with low NIHSS.Disclosures I. Abecassis: 2; C; IschemaView (Rapid), Remedy Robotics. E. Almallouhi: None. R. Chalhoub: None. S. Kassab: None. E. Bass: None. D. Ding: None. I. Mai...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Abecassis, I., Almallouhi, E., Chalhoub, R., Kassab, S., Bass, E., Ding, D., Maier, I., Psychogios, M., Liman, J., Alawieh, A., Wolfe, S., Arthur, A., Kan, P., Kim, J., De Leacy, R., Osbun, J., Jabbour, P., Grossbereg, J., Park, M., Mascitelli, J., Levitt Tags: SNIS 19th annual meeting oral abstracts Source Type: research

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