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Source: European Respiratory Journal
Condition: Ischemic Stroke

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Total 44 results found since Jan 2013.

Reply: Association between triple therapy and major adverse cardiovascular events in COPD patients
We thank P. Almagro and P. Martinez-Camblor for their interest in our work and for their salient comments. While we agree that there is no universally accepted definition of major adverse cardiovascular event (MACE), the US Food and Drug Administration (FDA) and the European Medicines Agency include nonfatal myocardial infarction and stroke as well as cardiovascular (CV) mortality in their MACE definition [1]. Importantly, this definition includes both haemorrhagic and ischaemic stroke [1–4]. In our study, we followed this classical "three-point" definition of MACE (including haemorrhagic strokes). While this definit...
Source: European Respiratory Journal - March 2, 2023 Category: Respiratory Medicine Authors: Yang, M.-J., Guo, S.-L., Sin, D. D. Tags: Correspondence Source Type: research

COPD and COVID-19: a dangerous association?
Conclusion: COPDs patients are mostly ederly men with comorbidities. The most effective treatment for them was stabilization of comorbidities and conventional oxygen and for the most severe Helmet-CPAP and NIV. In addition, COPD patients had no higher risk of mortality from COVID-19 than individuals without a pre-existing diagnosis of COPD.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Mendez Gonzalez, L., Ferreira, J., Caneiras, C. Tags: 05.02 - Monitoring airway disease Source Type: research

Impact of cardiovascular disease on in-hospital mortality in patients with COVID-19
Conclusion: COVID-19 patients with CVD comorbidites have a higher risk of in-hospital death. Optimal care and good control of CVD are essential in this patient group.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Pencheva Genova, V., Pancheva, R., Stoimenov, B., Manov, E., Kolev, V., Tsrancheva, R., Koshtikova, K., Stoianov, D., Donev, S. Tags: 01.01 - Clinical problems - no related to asthma or COPD Source Type: research

Prevalence of cardiovascular disease in alpha-1 antrypsin deficiency
We present prevalence of CVD from 1158 patients with AATD who are prospectively followed up as part of the Birmingham AATD registry in the UK. All diagnoses come from either central NHS records or patient reports.The prevalence of CVD was as follows: ischaemic heart disease, 5.2%; heart failure, 0.7%, myocardial infarction, 0.9%; stroke, 1.9%; atrial fibrillation 2.4%. Hypertension and hyperlipidaemia were present in 22% and 10.7% of patients respectively. Factors associated with a higher prevalence of CVD include being male (p <0.001), older age (p <0.001), lower KCO (p = 0.008) and presence of hyperlipidaemia ...
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Bailey, E., Ellis, P., Turner, A., Ellis, P. Tags: 05.02 - Monitoring airway disease Source Type: research

Moderate obstructive sleep apnea and cardiovascular outcomes in elder patients: a propensity score matched, multicentric study (CPAGE-MODE study)
Conclusions: CPAP treatment did not reduce the probability of CVE in elders with moderate OSA. Characteristics CPAP group (N = 118) Usual care (N = 118) p-valueAge, years75.9 (4.9)76.0 (4.5)0.67Males56 (47.4)59 (50.0)0.43Body mass index, kg/m230.3 (4.9)30.5 (5.9)0.97Without previous CVE80 (67.8)81 (68.6)1.00Epworth score8.2 (4.4)8.3 (4.4)0.89AHI, events/hour20.3 (4.1)20.1 (4.3)0.78T90%, %9.65 (2.9 – 33.0)10.0 (3.0 – 25.3)0.90
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Teran Tinedo, J. R., Cano Pumarega, I., Diaz Cambriles, T., Garcia Sanchez, A., Gomez Garcia, T., Landete Rodriguez, P., Lores Gutierrez, V., Manas Baena, E., Troncoso Acevedo, M. F., Zamora Garcia, E., Lopez-Padilla, D. Tags: Sleep and control of breathing Source Type: research

Prevalence of Cardiometabolic Disease in the Greek Sleep Apnea Patients Cohort
Conclusions: We conclude that cardiometabolic disease was very prevalent in our SAP with moderate-severe sleep apnea. Our population consisted mainly of male, obese, middle aged patients. It is of grate interest the high percentage of comorbidities, especially that of arrythmias. Further analysis is needed, in order to identify different phenotypes and the subsequent personalized therapeutic approach.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Trakada, G., Dimitriadis, V., Amfilochiou, A., Siopi, D., Paschidou, V., Alexopoulou, C., Varsou, G., Konstantinidis, A., Steiropoulos, P., Pataka, A., Karachristos, C., Agrafiotis, M., Chasiotou, A., Tselepi, C., Kallianos, A., Fountoulaki, M., Gounidis, Tags: Sleep and control of breathing Source Type: research

Brainstem strokes are associated with increased obstructive apnea index during sleep acutely after stroke
Sleep-disordered breathing (SDB) and ischemic stroke are intertwined pathologies. Stroke topography may influence SDB presentation. We investigated the association of stroke topography with obstructive (OAI) and central apnea indices (CAI) in acute and subacute stroke.The prospective multicentre SAS-CARE study included 204 stroke patients. Demographic, anthropometric and stroke characteristics were recorded at admission. Stroke topography (left- and right-sided, supra- and infratentorial, cortical, subcortical, insular, brainstem, cerebellar) was visually scored on the MRI at admission and binary coded. Polysomnography was...
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Filchenko, I., Dekkers, M., Baillieul, S., Seiler, A., Schmidt, M., Bernasconi, C., Bassetti, C. Tags: Sleep and control of breathing Source Type: research

Association between COPD exacerbations and acute cardiovascular events: a systematic literature review
Conclusion: There was an increased risk of acute CV events following a COPD exacerbation. Further research is needed to confirm whether preventing COPD exacerbations also decreases the risk of a subsequent acute CV event.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Müllerova, H., Marshall, J., De Nigris, E., Varghese, P., Pooley, N., Embleton, N., Marjenberg, Z. Tags: Airway pharmacology and treatment Source Type: research

Thromboembolic events in COVID-19 patients : A Tunisian case series study
Coronavirus disease 2019 (COVID-19) can lead to systemic coagulation activation and thrombotic complications(TC), which may lead to fatal outcomes if not diagnosed and managed appropriately.We aimed to report the incidence and characteristics of venous and arterial thrombotic complications(TC) in hospitalized patients with COVID-19 and to investigate the predictive factors of their occurrence.A retrospective study including 200 patients with COVID-19 confirmed by a reverse transcription polymerase chain reaction test, admitted between March 2020 and January 2021 in the pulmonary departement B at Abderrahman Mami Hospi...
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Louhaichi, S., Ferchichi, M., Khalfallah, I., Belkhir, S., Boubaker, N., Ammar, J., Hamdi, B., Hamzaoui, A. Tags: Respiratory infections and bronchiectasis Source Type: research

Lung function and cardiovascular disease: a two-sample Mendelian randomisation study
Conclusion There is strong evidence that reduced FVC is independently and causally associated with coronary artery disease. Although the mechanism remains unclear, FVC could be taken into consideration when assessing cardiovascular risk and considered a potential target for reducing cardiovascular events. FEV1 and airflow obstruction do not appear to cause increased cardiovascular events; confounding and collider bias may explain previous findings of a causal association.
Source: European Respiratory Journal - September 9, 2021 Category: Respiratory Medicine Authors: Higbee, D. H., Granell, R., Sanderson, E., Davey Smith, G., Dodd, J. W. Tags: Genetics Original Articles: Genetics Source Type: research

Accelerated FEV1 decline and risk of cardiovascular disease and mortality in a primary care population of COPD patients
Accelerated lung function decline has been associated with increased risk of cardiovascular disease (CVD) in a general population, but little is known about this association in chronic obstructive pulmonary disease (COPD). We investigated the association between accelerated lung function decline and CVD outcomes and mortality in a primary care COPD population. COPD patients without a history of CVD were identified in the Clinical Practice Research Datalink (CPRD)-GOLD primary care dataset (n=36 382). Accelerated decline in forced expiratory volume in 1 s (FEV1) was defined using the fastest quartile of the COPD popula...
Source: European Respiratory Journal - March 4, 2021 Category: Respiratory Medicine Authors: Whittaker, H. R., Bloom, C., Morgan, A., Jarvis, D., Kiddle, S. J., Quint, J. K. Tags: COPD and smoking Original Articles: COPD Source Type: research

Aspirin reduces cardiovascular events in patients with pneumonia: a prior event rate ratio analysis in a large primary care database
This study provides supporting evidence that aspirin use is associated with reduced ischaemic events after pneumonia in a primary care setting. This drug may have a future clinical role in preventing this important complication.
Source: European Respiratory Journal - February 11, 2021 Category: Respiratory Medicine Authors: Hamilton, F., Arnold, D., Henley, W., Payne, R. A. Tags: Original Articles: Pulmonary infection Source Type: research

Relation between respiratory diseases and the development of cardiovascular events in patients with respiratory viral infection
Conclusions: COPD does not seem to be an additional risk factor for the development of CVE in patients with respiratory viral infections. However, patients with CVRF and previous CVE more frequently developed new CVE. Patients with CVRF without COPD developed more CVE.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Zambrano Chacon, M. D. L. A., Esteban-Lucia, L., Izquierdo Perez, A., Nieto Roca, L., Venegas Rodriguez, A. M., Garcia Talavera, C. S., Pello Lazaro, A. M., Acena Navaroo, A., Villar Alvarez, F. Tags: Respiratory infections Source Type: research

30-day Readmissions After Acute Exacerbations of COPD: How Relevant Are Comorbidities?
Conclusions: Cardiovascular diseases were highly prevalent and acute heart failure was an important cause of 30-day readmission among AECOPD patients. GERD may complicate AECOPD recovery and patients with previous stroke may be at higher risk of a fatal outcome.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Freitas, C., Dias, J., Leuschner, P. Tags: Monitoring airway disease Source Type: research

The syndrome of respiratory failure in acute stroke patients
Conclusions: The assessment for respiratory failure (arterial blood gasses) should include in routine diagnostic protocol for all acute stroke patients. t-He/O2 effective treatment option for that category of patients since it improves clinical neurologic disability and respiratory failure symptoms.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Kim, T., Chuchalin, A., Gusev, E., Martynov, M., Shogenova, L., Panin, A. Tags: Acute critical care Source Type: research