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Source: European Respiratory Journal
Condition: Heart Disease
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Total 29 results found since Jan 2013.
COPD and COVID-19: a dangerous association?
Conclusion: COPDs patients are mostly ederly men with comorbidities. The most effective treatment for them was stabilization of comorbidities and conventional oxygen and for the most severe Helmet-CPAP and NIV. In addition, COPD patients had no higher risk of mortality from COVID-19 than individuals without a pre-existing diagnosis of COPD.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Mendez Gonzalez, L., Ferreira, J., Caneiras, C. Tags: 05.02 - Monitoring airway disease Source Type: research
Comorbidities in patients with Obstructive Sleep Apnea syndrome (OSAS) in Reunion Island.
Conclusion: Morbid obesity, hypertension, diabetes, heart disease and respiratory illness are a predictor of severe OSAS in our patients especially snorers.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Omarjee, B., Budhan, S., Kichenin, C., Omarjee, A., Vellin, J. F. Tags: 01.01 - Clinical problems - no related to asthma or COPD Source Type: research
Prevalence of cardiovascular disease in alpha-1 antrypsin deficiency
We present prevalence of CVD from 1158 patients with AATD who are prospectively followed up as part of the Birmingham AATD registry in the UK. All diagnoses come from either central NHS records or patient reports.The prevalence of CVD was as follows: ischaemic heart disease, 5.2%; heart failure, 0.7%, myocardial infarction, 0.9%; stroke, 1.9%; atrial fibrillation 2.4%. Hypertension and hyperlipidaemia were present in 22% and 10.7% of patients respectively. Factors associated with a higher prevalence of CVD include being male (p <0.001), older age (p <0.001), lower KCO (p = 0.008) and presence of hyperlipidaemia ...
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Bailey, E., Ellis, P., Turner, A., Ellis, P. Tags: 05.02 - Monitoring airway disease Source Type: research
Moderate obstructive sleep apnea and cardiovascular outcomes in elder patients: a propensity score matched, multicentric study (CPAGE-MODE study)
Conclusions: CPAP treatment did not reduce the probability of CVE in elders with moderate OSA. Characteristics CPAP group (N = 118) Usual care (N = 118) p-valueAge, years75.9 (4.9)76.0 (4.5)0.67Males56 (47.4)59 (50.0)0.43Body mass index, kg/m230.3 (4.9)30.5 (5.9)0.97Without previous CVE80 (67.8)81 (68.6)1.00Epworth score8.2 (4.4)8.3 (4.4)0.89AHI, events/hour20.3 (4.1)20.1 (4.3)0.78T90%, %9.65 (2.9 – 33.0)10.0 (3.0 – 25.3)0.90
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Teran Tinedo, J. R., Cano Pumarega, I., Diaz Cambriles, T., Garcia Sanchez, A., Gomez Garcia, T., Landete Rodriguez, P., Lores Gutierrez, V., Manas Baena, E., Troncoso Acevedo, M. F., Zamora Garcia, E., Lopez-Padilla, D. Tags: Sleep and control of breathing Source Type: research
Prevalence of Cardiometabolic Disease in the Greek Sleep Apnea Patients Cohort
Conclusions: We conclude that cardiometabolic disease was very prevalent in our SAP with moderate-severe sleep apnea. Our population consisted mainly of male, obese, middle aged patients. It is of grate interest the high percentage of comorbidities, especially that of arrythmias. Further analysis is needed, in order to identify different phenotypes and the subsequent personalized therapeutic approach.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Trakada, G., Dimitriadis, V., Amfilochiou, A., Siopi, D., Paschidou, V., Alexopoulou, C., Varsou, G., Konstantinidis, A., Steiropoulos, P., Pataka, A., Karachristos, C., Agrafiotis, M., Chasiotou, A., Tselepi, C., Kallianos, A., Fountoulaki, M., Gounidis, Tags: Sleep and control of breathing Source Type: research
Determinants of blood eosinophil count in adults from a large population-based study
Factors not associated with respiratory disease that influence blood eosinophil (B-Eos) count have not been clearly defined. We aimed to evaluate the influence of non-respiratory diseases on B-Eos count and to identify individual characteristics, including gender and body mass index, associated with B-Eos count in individuals without respiratory disease.Individuals (18-85 years) with complete B-Eos data from the US National Health and Nutritional Examination Surveys 2005–2016 were grouped as having respiratory disease (n=7,894) or not having respiratory disease (n=15,010). Among those without respiratory disease, non...
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Amaral, R., Jacinto, T., Malinovschi, A., Janson, C., Price, D., Fonseca, J., Alving, K. Tags: Monitoring airway disease Source Type: research
Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health
There is currently limited understanding of the genetic aetiology of obstructive sleep apnoea (OSA). We aimed to identify genetic loci associated with OSA risk, and to test if OSA and its comorbidities share a common genetic background.
We conducted the first large-scale genome-wide association study of OSA using the FinnGen study (217 955 individuals) with 16 761 OSA patients identified using nationwide health registries.
We estimated 0.08 (95% CI 0.06–0.11) heritability and identified five loci associated with OSA (p<5.0x10–8): rs4837016 near GAPVD1 (GTPase activating protein and VPS9 domains 1), rs1092856...
Source: European Respiratory Journal - May 6, 2021 Category: Respiratory Medicine Authors: Strausz, S., Ruotsalainen, S., Ollila, H. M., Karjalainen, J., Kiiskinen, T., Reeve, M., Kurki, M., Mars, N., Havulinna, A. S., Luonsi, E., Mansour Aly, D., Ahlqvist, E., Teder-Laving, M., Palta, P., Groop, L., Mägi, R., Mäkitie, A., Salom Tags: Sleep medicine Original Articles: Sleep medicine Source Type: research
Cutting the fat: advances and challenges in sleep apnoea genetics
Obstructive sleep apnoea (OSA), characterised by recurrent upper airway obstruction, intermittent hypoxia and fragmented sleep, affects >15% of the adult population, with prevalence increasing markedly with advancing age and age-related cardiometabolic and pulmonary disorders [1]. Causal associations between OSA and hypertension, coronary heart disease, diabetes, heart failure, atrial fibrillation, stroke and mortality are suggested by numerous large prospective studies [2], raising the possibility that effective treatment of OSA might provide a novel strategy for primary and secondary prevention of cardiometabolic dise...
Source: European Respiratory Journal - May 6, 2021 Category: Respiratory Medicine Authors: Wang, H., Goodman, M. O., Sofer, T., Redline, S. Tags: Editorials Source Type: research
30-day Readmissions After Acute Exacerbations of COPD: How Relevant Are Comorbidities?
Conclusions: Cardiovascular diseases were highly prevalent and acute heart failure was an important cause of 30-day readmission among AECOPD patients. GERD may complicate AECOPD recovery and patients with previous stroke may be at higher risk of a fatal outcome.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Freitas, C., Dias, J., Leuschner, P. Tags: Monitoring airway disease Source Type: research
Conicity index as prognostic factor of major cardiovascular events in obstructive sleep apnea
Conclusions: CI presented a higher association with CVE than BMI. Logistic egression of CVE and CIVariableORCI95p-valueAge1.051.02 - 1.080.001Women0.360.16 - 0.830.016Diabetes2.321.02 - 5.250.045Conicity index3.921.69 - 9.100.001Logistic regression of CVE and CIAge1.071.03 - 1.100.001Women0.420.19 - 0.960.040Diabetes2.281.01 - 5.140.045BMI2.411.09 - 5.320.029
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Lopez-Padilla, D., Teran Tinedo, J. R., Llanos Flores, M., Jimeno, E. R., Ji, Z., Gallo Gonzalez, V., Cerezo Lajas, A., Ojeda Castillejo, E., Lopez Martin, S., Puente Maestu, L. Tags: Sleep and control of breathing Source Type: research
Characteristics of patients treated with nicotine replacement therapy (NRT) prescribed during hospitalization
Conclusions: The follow-up after discharge in specialized units of tobacco cessation is very low, yet the efficacy of the treatment per year was high.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Perez Morales, M., Espana Dominguez, C., Morales Gonzalez, M., Munoz Ramirez, I., Merino Sanchez, M., Arnedillo Munoz, A. Tags: Tobacco, smoking control and health educ. Source Type: research
Magnitude and characteristics of COPD mortality in Kenya, 2012-2016
The objective of the study was to estimate the magnitude and characteristics of COPD mortality in Kenya.This was a retrospective analysis of mortality and cause of death through a systematic review of hospital medical records. Data collected covered a 5-year period from 2012- 2016 from selected hospitals in all 47 counties. Purposive sampling of county referral hospitals and the three national referral hospitals was done, while sub-county and faith-based hospitals were selected using stratified sampling. Data were abstracted from medical records and then coded using ICD-10. Data analysis was done using MS Excel 2016, with ...
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Kariuki, G., Gathecha, G. Tags: Epidemiology Source Type: research
Obstructive sleep apnea and cardiovascular risk in Chinese population: a Meta-analysis
Conclusions: This meta-analysis of prospective cohort studies suggests that OSA significantly increases the risk of CHD, stroke and CCVD in Chinese population.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Ye, J., Li, J., Xu, J., Yin, G., Zhan, S. Tags: Clinical Problems Others Source Type: research
Association of inflammatory biomarkers with comorbidity in chronic obstructive pulmonary disease - results from the COSYCONET cohort
Conclusion: WBC correlates with disease severity and is associated with relevant comorbidities. Other classical inflammatory biomarkers did not show a clear correlation with COPD severity of existing comorbidity.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Seiler, F., Trudzinski, F. C., Alquadrah, M., Fähndrich, S., Watz, H., Jörres, R. A., Koch, A., Welte, T., Vogelmeier, C. F., Biertz, F., Bals, R. Tags: Monitoring Airway Disease Source Type: research
Cardiovascular comorbidity in Danish patients with scleroderma-associated interstitial lung disease
Conclusion: CC was frequent among patients with SSc-ILD but was not associated with increased mortality. As expected, PH was associated with severe excess mortality.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Madsen, G. A., Hyldgaard, C., Bendstrup, E. Tags: Diffuse Parenchymal Lung Disease Source Type: research
