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Source: JAMA Neurology
Condition: Stroke

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Total 364 results found since Jan 2013.

Stereotypy After Acute Thalamic Infarct
This Images in Neurology article summarizes clinical features, diagnosis, and management of post-stroke stereotypy.
Source: JAMA Neurology - July 13, 2015 Category: Neurology Source Type: research

Risk of Stroke at the Time of Carotid Occlusion
This study of patients undergoing carotid ultrasonography reports that the risk of carotid occlusion is well below the risk of carotid stenting or endarterectomy and decreases markedly with more intensive medical therapy.
Source: JAMA Neurology - September 21, 2015 Category: Neurology Source Type: research

Acute Ischemic Stroke Therapy
This Viewpoint discusses the future of thrombolysis and thrombectomy for patients with acute brain ischemia.
Source: JAMA Neurology - October 5, 2015 Category: Neurology Source Type: research

Coexistent Small Vessel Disease and Intracranial Arterial Stenosis
This post hoc analysis of a clinical trial evaluated the risk of ischemic stroke in patients with large artery atherosclerosis and coexistent small vessel disease.
Source: JAMA Neurology - November 30, 2015 Category: Neurology Source Type: research

Place of Neuroimaging in Cerebral Small Vessel Disease
The burden of cerebrovascular disease is high: each year, approximately 795 000 people in the United States experience a new or recurrent stroke, leading to death in 128 824 individuals or being associated with death in 215 864 cases. However, the number of silent infarcts and microhemorrhages is much higher, causing cognitive and behavioral impairment in 17% of the population older than 65 years. These usually primarily asymptomatic events are often caused by cerebral small vessel disease (SVD) detected as white matter hyperintensities, lacunas, microbleeds, and cortical and subcortical atrophy in magnetic resonance...
Source: JAMA Neurology - February 1, 2016 Category: Neurology Source Type: research

Affiliation Error in Group Information Listing
This article was corrected online and in print.
Source: JAMA Neurology - February 8, 2016 Category: Neurology Source Type: research

Omitted Author Affiliation
This article was corrected online.
Source: JAMA Neurology - February 22, 2016 Category: Neurology Source Type: research

Prediction of Early Recurrence After Acute Ischemic Stroke
This study tests the validity of a prognostic score that was exclusively developed to predict early risk of recurrence in a multicenter setting.
Source: JAMA Neurology - February 29, 2016 Category: Neurology Source Type: research

Strokelike Episode Management in Patients With Mitochondrial Syndromes
This review details the current understanding of the cause of strokelike episodes in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS) and presents recommendations to assist in the identification and treatment of patients with MELAS presenting with stroke.
Source: JAMA Neurology - March 7, 2016 Category: Neurology Source Type: research

Obesity, Oral Contraceptive Use, and Cerebral Venous Thrombosis
Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that primarily affects young adults. A unique risk factor profile and plurality of presenting features make it an elusive diagnosis unless a high index of suspicion is maintained. It comprises approximately 0.5% to 1% of all strokes, and widespread availability of magnetic resonance imaging has made recognition easier. The International Study on Cerebral Vein and Dural Sinus Thrombosis is the largest prospective, multinational, observational study of patients with CVT to date, including 624 consecutive patients with symptomatic CVT at 89 centers between May ...
Source: JAMA Neurology - March 15, 2016 Category: Neurology Source Type: research

Potential Association Between Atrial Fibrillation and Dementia
In Reply We thank Chen and colleagues for their interest in our work and are pleased that our report triggers debate about the optimal treatment of atrial fibrillation (AF) to prevent dementia, in addition to stroke and other thromboembolic complications of AF.
Source: JAMA Neurology - March 21, 2016 Category: Neurology Source Type: research

Hemodynamics in Atherosclerotic Vertebrobasilar Occlusive Disease
In Reply We read with interest the letter by Walcott et al and thank them for their insightful comments. They note that whereas in carotid stenosis, artery-to-artery embolism is a common culprit, hypoperfusion as determined by the Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke protocol is the main pathological mechanism in patients with vertebrobasilar disease and low-flow status. In their experience, a number of patients with medically refractory vertebrobasilar disease symptoms were successfully treated with surgical revascularization in the form of a microsurgical bypass and they make t...
Source: JAMA Neurology - April 18, 2016 Category: Neurology Source Type: research

Worsening Stroke Symptoms in an 80-Year-Old Man
An 80-year-old man presented to the hospital with new-onset slurred speech and left-sided facial droop. Magnetic resonance imaging scans of the head were visually interpreted to show an acute infarct involving the posterior right frontal lobe. What is your diagnosis?
Source: JAMA Neurology - June 6, 2016 Category: Neurology Source Type: research

Cerebral Microbleeds, Cognition and Therapeutic Implications
A recent major clinical advance in magnetic resonance imaging (MRI) of the brain is the development of paramagnetic-sensitive sequences such as T2-weighted gradient-recalled echo and susceptibility-weighted images for the detection of cerebral microbleeds (CMBs). On brain MRI, CMBs are small (≤5 to 10 mm in diameter), round, dark-signaled lesions that consist of extravasation of blood components through fragile microvascular walls that neuropathologically represent hemosiderin-laden macrophages. Magnetic resonance imaging–detected CMBs are common in elderly individuals, coexist with ischemic stroke and intracerebral he...
Source: JAMA Neurology - June 6, 2016 Category: Neurology Source Type: research

Dementia After Intracerebral Hemorrhage
As acute management of intracerebral hemorrhage (ICH) has improved, more patients survive ICH but are left with significant deficits. In the past, primary evaluations of outcomes after ICH have focused on mortality and levels of functional dependence, with a relatively modest number of patients experiencing true functional independence after ICH or returning to their previous level of functioning. Cognitive outcomes after ICH have thus not been a primary focus of either treatment or natural history studies of ICH, despite their known importance after ischemic stroke and their importance in predicting return to previous functioning.
Source: JAMA Neurology - June 13, 2016 Category: Neurology Source Type: research