Strokelike Episode Management in Patients With Mitochondrial Syndromes
This review details the current understanding of the cause of strokelike episodes in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS) and presents recommendations to assist in the identification and treatment of patients with MELAS presenting with stroke.
The key habits to adopt are daily exercise, consuming less junk food and alcohol, not smoking and shedding a few pounds if overweight.
Women well into middle age can still reduce their risk for stroke by eating well, exercising and not smoking, according to a new study published Thursday in the journal Stroke.
Background: Even with antiretroviral therapy (ART), persons with HIV (PWH) experience increased morbidity and mortality. Cytomegalovirus (CMV) and Epstein--Barr virus (EBV) co-infections likely exacerbate inflammatory-related diseases. Objective: To determine if presence of detectable CMV or EBV DNA in peripheral blood mononuclear cells (PBMC) is associated with non-AIDS events among PWH receiving modern ART. Design: We performed a case--control study of PWH starting ART and HIV-suppressed at year 1 and thereafter, 140 cases who experienced non-AIDS events and 305 matched controls. Events included myocardial infarc...
Authors: Maranta F, Cianfanelli L, Cianflone D Abstract Diabetes mellitus is constantly increasing worldwide. Vascular complications are the most common in the setting of long-standing disease, claiming the greatest burden in terms of morbidity and mortality. Glucotoxicity is involved in vascular damage through different metabolic pathways, such as production of advanced glycation end-products, activation of protein kinase C, polyol pathway activation and production of reactive oxygen species. Vascular complications can be classified according to the calibre of the vessels involved as microvascular (such as diabeti...
In this study, we hypothesised that elevated serum TN-C at enrolment in participants with type 2 diabetes would be associated with increased risk of death and major adverse CV events (MACE) during follow-up.MethodsWe used a prospective, monocentric cohort of consecutive type 2 diabetes participants (the SURDIAGENE [SUivi R énal, DIAbète de type 2 et GENEtique] cohort) with all-cause death as a primary endpoint and MACE (CV death, non-fatal myocardial infarction or stroke) as a secondary endpoint. We used a proportional hazard model after adjustment for traditional risk factors and the relative integrated disc...
Stroke specialists across the country are reporting a drop in the number of patients seeking emergency care during the COVID-19 pandemic.
Conclusion Three-year prognosis in unstable angina was considerable better in comparison with NSTEMI. On the contrary, after adjustment for baseline differences, the outcomes (death, MI, MACE) in unstable angina and stable angina patients were comparable.
Conclusions: Patients undergoing protected high-risk percutaneous coronary intervention with Impella support showed an acceptable 180-day clinical outcome regarding major adverse cardiac event and mortality.
Publication date: Available online 8 April 2020Source: American Heart JournalAuthor(s): Yingying Yang, Zhonghe Zhou, Yuesong Pan, Huisheng Chen, Yilong Wang, On Behalf of the ARAIS Protocol Steering Group
Condition: Stroke Intervention: Other: rehabilitation intervention Sponsor: University of East Anglia Recruiting