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Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza
This cohort study compares the rate of ischemic stroke among patients with COVID-19 vs patients with influenza in 2 hospitals in New York City, New York.
Source: JAMA Neurology - July 2, 2020 Category: Neurology Source Type: research

Prognosis of Cryptogenic Stroke With Patent Foramen Ovale at Older Ages and Implications for Trials
This systematic review and meta-analysis examines the recurrence of ischemic stroke and possible use of patent foramen ovale closure in patients aged 60 years or older.
Source: JAMA Neurology - July 6, 2020 Category: Neurology Source Type: research

Perioperative Stroke Risk Reduction in Patients With Patent Foramen Ovale
This Viewpoint considers ischemic stroke risk for patients with a patent foramen ovale.
Source: JAMA Neurology - August 3, 2020 Category: Neurology Source Type: research

Endovascular Treatment After Stroke Due to Large Vessel Occlusion for Patients Presenting Very Late
This case-control study examines the prevalence of salvageable tissues 16 hours or more from the time the patient was last known well after ischemic stroke due to emergent large vessel occlusion and investigates the effectiveness of endovascular treatment in delayed large vessel occlusion.
Source: JAMA Neurology - August 10, 2020 Category: Neurology Source Type: research

Reperfusion Therapy for In-Hospital Ischemic Stroke in the Endovascular Therapy Era
This cohort study uses a large US national registry to assess temporal trends from 2008 to 2018 in the use of intravenous and endovascular reperfusion therapies, process measures of quality, and association between functional outcomes and key patient characteristics, comorbidities, and treatments of in-hospital vs out-of-hospital stroke onset.
Source: JAMA Neurology - September 21, 2020 Category: Neurology Source Type: research

Remote Ischemic Perconditioning for the Treatment of Acute Ischemic Stroke
To the Editor We read with interest the article by Pico et al, who reported the results of a randomized clinical trial to determine whether remote ischemic perconditioning can reduce brain infarction volume growth in patients with acute ischemic stroke. In the study, treatment with remote ischemic perconditioning had no significant effect on brain infarction volume growth at 24 hours after symptom onset. Two main hypotheses were proposed for the neutral results: remote ischemic perconditioning may not have any beneficial effect, or this trial mainly recruited patients who had received reperfusion therapies. However, we con...
Source: JAMA Neurology - September 28, 2020 Category: Neurology Source Type: research

Ischemic Stroke Incidence Trends After Transient Ischemic Attack
This systematic review and meta-analysis calculates the pooled event rate for ischemic stroke within 2, 7, 30, and 90 days of a transient ischemic attack and compares this incidence among patients recruited before 1999, from 1999 to 2007, and after 2007.
Source: JAMA Neurology - October 12, 2020 Category: Neurology Source Type: research

Prediction of Early Neurological Deterioration in Minor Stroke and LVO Intended for Intravenous Thrombolysis
This cohort study aims to develop and validate an easily applicable predictive score of early neurological deterioration of presumed ischemic origin following intravenous thrombolysis in patients with minor stroke and large vessel occlusion (LVO).
Source: JAMA Neurology - January 11, 2021 Category: Neurology Source Type: research

Reperfusion Treatment and Stroke Outcomes in Hospitals With Telestroke Capacity
This study describes differences in care patterns and outcomes among patients with acute ischemic stroke who present to hospitals with and without telestroke capacity.
Source: JAMA Neurology - March 1, 2021 Category: Neurology Source Type: research

Complexities of Reperfusion Therapy in Patients With Ischemic Stroke Pretreated With Direct Oral Anticoagulants
This Viewpoint describes current issues with the use of thrombolysis in patients who have acute ischemic stroke but have recently been or are concurrently being treated with direct oral anticoagulation.
Source: JAMA Neurology - March 15, 2021 Category: Neurology Source Type: research

Administering Thrombolysis for Acute Ischemic Stroke in Patients Taking Direct Oral Anticoagulants
This Viewpoint discusses the when and how to best administer thrombolysis for patients with acute ischemic stroke taking direct oral anticoagulants.
Source: JAMA Neurology - March 15, 2021 Category: Neurology Source Type: research

Healthy Life-Year Costs From Arrival to Endovascular Thrombectomy in Patients With Ischemic Stroke
This meta-analysis evaluates outcomes along the full health-related quality-of-life range associated with time to endovascular thrombectomy in patients with ischemic stroke.
Source: JAMA Neurology - May 3, 2021 Category: Neurology Source Type: research

Questions on Predicting Early Neurological Deterioration in Patients With Minor Stroke and Large-Vessel Occlusion —Reply
In Reply We thank Ospel and colleagues for their thoughtful comments on our article showing that more proximal occlusion and greater thrombus length predict early neurological deterioration of ischemic origin (ENDi) in patients with acute minor ischemic stroke with large-vessel occlusion treated with intravenous thrombolysis, with implications regarding how to best manage these patients. Although the precise pathophysiological links between more proximal occlusion, a longer thrombus, and ENDi are uncertain, we fully agree that a leading hypothesis is in situ thrombus extension leading to secondary hemodynamic compromise vi...
Source: JAMA Neurology - July 6, 2021 Category: Neurology Source Type: research

Multiple Facial Ulcers Following a Stroke
A 66-year-old man presents with multiple progressive ulcers and hypesthesia on the right side of his face, new-onset hemiplegia and hemianopsia on the left side of his face, and ischemic posterior circulation stroke. What is your diagnosis?
Source: JAMA Neurology - July 19, 2021 Category: Neurology Source Type: research

Direct to Angiography Suite Without Stopping for Computed Tomography Imaging in Acute Stroke
This randomized clinical trial assesses whether direct transfer to the angiography suite improves clinical outcomes compared with usual imaging workflow among patients within 6 hours from onset of symptoms for large vessel occlusion ischemic stroke.
Source: JAMA Neurology - August 2, 2021 Category: Neurology Source Type: research

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