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Disentangling Workflow Paradigms and Treatment Decision-making in Acute Ischemic Stroke
To the Editor We congratulate Requena and colleagues on their randomized trial, in which they compared a direct-to-angiography suite (DTAS) paradigm with a conventional workflow paradigm, ie, cross-sectional imaging, followed by transport to the angiography suite for endovascular treatment (EVT) when appropriate. The authors found that a DTAS paradigm not only decreased in-hospital workflow times but also increased the odds of patients undergoing EVT, both of which may have contributed to the improved clinical outcomes in the DTAS group.
Source: JAMA Neurology - February 7, 2022 Category: Neurology Source Type: research

Outcomes After Endovascular Thrombectomy With or Without Alteplase in Routine Clinical Practice
This cohort study investigates the outcomes of combination endovascular thrombectomy with alteplase compared with endovascular thrombectomy alone for the treatment of patients with acute ischemic stroke attributable to large vessel occlusion.
Source: JAMA Neurology - June 13, 2022 Category: Neurology Source Type: research

Time for a New Perspective on Intracerebral Hemorrhage
More than 3 million people worldwide experience intracerebral hemorrhage (ICH) each year. Although the incidence of ICH is much lower than that of ischemic stroke, ICH imposes a 50% greater worldwide burden of disability. ICH has a 30-day case fatality rate of more than 40%, and most survivors are left with permanent disabilities. Because of the high likelihood of poor outcomes, physicians caring for patients with ICH tend to use clinical severity scores early on to estimate the risk of mortality or future disability to determine the aggressiveness of medical care and to guide conversations with patients ’ surrogates aro...
Source: JAMA Neurology - July 25, 2022 Category: Neurology Source Type: research

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants
This cohort study evaluates the risk of symptomatic intracranial hemorrhage associated with use of intravenous thrombolysis in patients with recent direct oral anticoagulant ingestion.
Source: JAMA Neurology - January 3, 2023 Category: Neurology Source Type: research

Error in Byline, Affiliations, and Table 1
This article was corrected online.
Source: JAMA Neurology - February 6, 2023 Category: Neurology Source Type: research

Multimodal Neuroimaging of Intimal Flap in a Basilar Artery Dissection
This case report describes a spontaneous dissection of the basilar artery in a 53-year-old man presenting with ischemic stroke.
Source: JAMA Neurology - March 13, 2023 Category: Neurology Source Type: research

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