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Source: The Lancet Neurology
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Total 249 results found since Jan 2013.
The pathway towards an effective reduction of stroke burden worldwide: teamwork
Publication date: July 2019Source: The Lancet Neurology, Volume 18, Issue 7Author(s): Gustavo Saposnik, Vladimir Hachinski
Source: The Lancet Neurology - June 13, 2019 Category: Neurology Source Type: research
Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data
Publication date: September 2019Source: The Lancet Neurology, Volume 18, Issue 9Author(s): Tom J Moullaali, Xia Wang, Reneé H Martin, Virginia B Shipes, Thompson G Robinson, John Chalmers, Jose I Suarez, Adnan I Qureshi, Yuko Y Palesch, Craig S AndersonSummaryBackgroundUncertainty persists over the effects of blood pressure lowering in acute intracerebral haemorrhage. We aimed to combine individual patient-level data from the two largest randomised controlled trials of blood pressure lowering strategies in patients with acute intracerebral haemorrhage to determine the strength of associations between key measures of systo...
Source: The Lancet Neurology - August 8, 2019 Category: Neurology Source Type: research
Computerised speech and language therapy in post-stroke aphasia
Publication date: September 2019Source: The Lancet Neurology, Volume 18, Issue 9Author(s): Agnes Flöel
Source: The Lancet Neurology - August 8, 2019 Category: Neurology Source Type: research
Long-term antithrombotic therapy and risk of intracranial haemorrhage from cerebral cavernous malformations: a population-based cohort study, systematic review, and meta-analysis
Publication date: Available online 7 August 2019Source: The Lancet NeurologyAuthor(s): Susanna M Zuurbier, Charlotte R Hickman, Christos S Tolias, Leon A Rinkel, Rebecca Leyrer, Kelly D Flemming, David Bervini, Giuseppe Lanzino, Robert J Wityk, Hans-Martin Schneble, Ulrich Sure, Rustam Al-Shahi Salman, Scottish Audit of Intracranial Vascular Malformations Steering CommitteeSummaryBackgroundAntithrombotic (anticoagulant or antiplatelet) therapy is withheld from some patients with cerebral cavernous malformations, because of uncertainty around the safety of these drugs in such patients. We aimed to establish whether antithro...
Source: The Lancet Neurology - August 8, 2019 Category: Neurology Source Type: research
Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study
This study is registered with ClinicalTrials.gov, number NCT02119182.FindingsBetween Feb 26, 2014, and June 15, 2018, we recruited 450 patients with normal head CT scans (of whom 330 had negative MRI scans and 120 had positive MRI scans), 122 orthopaedic trauma controls, and 209 healthy controls. AUC for GFAP in patients with CT-negative and MRI-positive findings versus patients with CT-negative and MRI-negative findings was 0·777 (95% CI 0·726–0·829) over 24 h. Median plasma GFAP concentration was highest in patients with CT-negative and MRI-positive findings (414·4 pg/mL, 25–75th percentile 139·3–813·4), foll...
Source: The Lancet Neurology - August 24, 2019 Category: Neurology Source Type: research
Global prevention of stroke: focus on the individual?
Publication date: October 2019Source: The Lancet Neurology, Volume 18, Issue 10Author(s): The Lancet Neurology
Source: The Lancet Neurology - September 14, 2019 Category: Neurology Source Type: research
Availability of stroke units in Colombia
Publication date: November 2019Source: The Lancet Neurology, Volume 18, Issue 11Author(s): Hernán Bayona-Ortiz, Juan Nicolás Useche, Nicolás Yanez, Sofia Catalina Velasco
Source: The Lancet Neurology - October 11, 2019 Category: Neurology Source Type: research
Support programme for secondary prevention of stroke: inspiration to continue?
Publication date: Available online 7 November 2019Source: The Lancet NeurologyAuthor(s): Linxin Li
Source: The Lancet Neurology - November 8, 2019 Category: Neurology Source Type: research
The gut microbiome in neurological disorders
Publication date: Available online 18 November 2019Source: The Lancet NeurologyAuthor(s): John F Cryan, Kenneth J O'Riordan, Kiran Sandhu, Veronica Peterson, Timothy G DinanSummaryResearch into the role of the gut microbiome in modulating brain function has rapidly increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and preclinical evidence implicates the microbiome as a possible key susceptibility factor for neurological disorders, including Alzheimer's disease, autism spectrum disorder, multiple sclerosis, Parkinson's disease, and stroke. Cross-sectional clinical studies are bolstering ...
Source: The Lancet Neurology - November 19, 2019 Category: Neurology Source Type: research
Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial
In this study, we aimed to investigate the safety and efficacy of endovascular treatment of acute strokes due to vertebrobasilar artery occlusion.MethodsWe did a multicentre, randomised, open-label trial, with blinded outcome assessment of thrombectomy in patients presenting within 8 h of vertebrobasilar occlusion at 28 centres in China. Patients were randomly assigned (1:1) to endovascular therapy plus standard medical therapy (intervention group) or standard medical therapy alone (control group). The randomisation sequence was computer-generated and stratified by participating centres. Allocation concealment was implemen...
Source: The Lancet Neurology - December 10, 2019 Category: Neurology Source Type: research
Stroke research in 2019: towards optimising treatment and prevention
Publication date: January 2020Source: The Lancet Neurology, Volume 19, Issue 1Author(s): Simiao Wu, Yajun Cheng, Bo Wu, Ming Liu
Source: The Lancet Neurology - December 12, 2019 Category: Neurology Source Type: research
Issues important to the design of stroke recovery trials
Publication date: March 2020Source: The Lancet Neurology, Volume 19, Issue 3Author(s): Steven C Cramer
Source: The Lancet Neurology - February 19, 2020 Category: Neurology Source Type: research
Prevalence, predictors, and prognosis of symptomatic intracranial stenosis in patients with transient ischaemic attack or minor stroke: a population-based cohort study
Publication date: May 2020Source: The Lancet Neurology, Volume 19, Issue 5Author(s): Robert Hurford, Frank J Wolters, Linxin Li, Kui Kai Lau, Wilhelm Küker, Peter M Rothwell, Oxford Vascular Study Phenotyped Cohort
Source: The Lancet Neurology - April 24, 2020 Category: Neurology Source Type: research
Refining endpoints for stroke recovery trials
Publication date: May 2020Source: The Lancet Neurology, Volume 19, Issue 5Author(s): Dirk M Hermann, Claudio L Bassetti, Ute Marx, Marie-Laure Audoli-Inthavong, Hugues Chabriat
Source: The Lancet Neurology - April 24, 2020 Category: Neurology Source Type: research
The fight against stroke must go on
Publication date: May 2020Source: The Lancet Neurology, Volume 19, Issue 5Author(s): The Lancet Neurology
Source: The Lancet Neurology - April 24, 2020 Category: Neurology Source Type: research
