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Diagnostic value of  alternative techniques to gadolinium-based contrast agents in MR neuroimaging—a comprehensive overview
AbstractGadolinium-based contrast agents (GBCAs) increase lesion detection and improve disease characterization for many cerebral pathologies investigated with MRI. These agents, introduced in the late 1980s, are in wide use today. However, some non-ionic linear GBCAs have been associated with the development of nephrogenic systemic fibrosis in patients with kidney failure. Gadolinium deposition has also been found in deep brain structures, although it is of unclear clinical relevance. Hence, new guidelines from the International Society for Magnetic Resonance in Medicine advocate cautious use of GBCA in clinical and resea...
Source: Insights into Imaging - August 22, 2019 Category: Radiology Source Type: research

Magnetic resonance imaging of arterial stroke mimics: a pictorial review
AbstractAcute ischaemic stroke represents the most common cause of new sudden neurological deficit, but other diseases mimicking stroke happen in about one-third of the cases. Magnetic resonance imaging (MRI) is the best technique to identify those ‘stroke mimics’. In this article, we propose a diagnostic approach of those stroke mimics on MRI according to an algorithm based on diffusion-weighted imaging (DWI), which can be abnormal or normal, followed by the results of other common additional MRI sequences, such as T2 with gradient recall ed echo weighted imaging (T2-GRE) and fluid-attenuated inversion recovery (FLAIR...
Source: Insights into Imaging - June 22, 2018 Category: Radiology Source Type: research