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Race and Ethnicity, Obesity, Metabolic Health, and Risk of Cardiovascular Disease in Postmenopausal Women Epidemiology
Conclusions Metabolic abnormalities appeared to convey more cardiovascular risk among black women.
Source: JAHA:Journal of the American Heart Association - May 20, 2015 Category: Cardiology Authors: Schmiegelow, M. D., Hedlin, H., Mackey, R. H., Martin, L. W., Vitolins, M. Z., Stefanick, M. L., Perez, M. V., Allison, M., Hlatky, M. A. Tags: Epidemiology Source Type: research

Patient Outcomes According to Adherence to Treatment Guidelines for Rhythm Control of Atrial Fibrillation Coronary Heart Disease
Conclusions Adherence to published guidelines in the antiarrhythmic management of AF is associated with improved patient outcomes.
Source: JAHA:Journal of the American Heart Association - April 6, 2015 Category: Cardiology Authors: Qin, D., Leef, G., Alam, M. B., Rattan, R., Munir, M. B., Patel, D., Khattak, F., Vaghasia, N., Adelstein, E., Jain, S. K., Saba, S. Tags: Coronary Heart Disease Source Type: research

Efficacy and Safety of Vorapaxar as Approved for Clinical Use in the United States Coronary Heart Disease
Conclusions In patients with prior MI or PAD who have not had a previous stroke or TIA, vorapaxar added to standard therapy is effective for long-term secondary prevention of thrombotic CV events, while increasing moderate or severe bleeding. Clinical Trial Registration URL: clinicaltrials.gov Unique Identifier: NCT00526474.
Source: JAHA:Journal of the American Heart Association - March 19, 2015 Category: Cardiology Authors: Magnani, G., Bonaca, M. P., Braunwald, E., Dalby, A. J., Fox, K. A. A., Murphy, S. A., Nicolau, J. C., Oude Ophuis, T., Scirica, B. M., Spinar, J., Theroux, P., Morrow, D. A. Tags: Coronary Heart Disease Source Type: research

Clinical Correlates and Prognostic Significance of Change in Standardized Left Ventricular Mass in a Community-Based Cohort of African Americans Epidemiology
Conclusions In our community-based sample of African Americans, baseline BMI and BP, and change in BP on follow-up were key determinants of increase in standardized log-LVMI, which in turn carried an adverse prognosis, underscoring the need for greater control of BP and weight in this group.
Source: JAHA:Journal of the American Heart Association - February 5, 2015 Category: Cardiology Authors: Fox, E. R., Musani, S. K., Samdarshi, T. E., Taylor, J. K., Beard, W. L., Sarpong, D. F., Xanthakis, V., McClendon, E. E., Liebson, P. R., Skelton, T. N., Butler, K. R., Mosley, T. H., Taylor, H., Vasan, R. S. Tags: Epidemiology Source Type: research

Predictors of Long-term Clinical Endpoints in Patients With Refractory Angina Coronary Heart Disease
Conclusions Clinically stable patients with RA who are medically managed have a modest mortality, but a high incidence of hospitalization and resource use over 3 years. These findings point to the need for novel therapies aimed at symptom mitigation in this population and their potential impact on health care utilization and costs.
Source: JAHA:Journal of the American Heart Association - January 30, 2015 Category: Cardiology Authors: Povsic, T. J., Broderick, S., Anstrom, K. J., Shaw, L. K., Ohman, E. M., Eisenstein, E. L., Smith, P. K., Alexander, J. H. Tags: Coronary Heart Disease Source Type: research

Habitual Sleep Duration and Predicted 10-Year Cardiovascular Risk Using the Pooled Cohort Risk Equations Among US Adults Epidemiology
Conclusions Mean-predicted 10-year cardiovascular risk was lowest among adults who reported sleeping 7 hours per night and increased as participants reported sleeping fewer and more hours.
Source: JAHA:Journal of the American Heart Association - December 2, 2014 Category: Cardiology Authors: Ford, E. S. Tags: Epidemiology Source Type: research

Electrocardiographic Deep Terminal Negativity of the P Wave in V1 and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities (ARIC) Study Coronary Heart Disease
Conclusion DTNPV1 is predictive of SCD suggesting its potential utility in risk stratification in the general population.
Source: JAHA:Journal of the American Heart Association - November 21, 2014 Category: Cardiology Authors: Tereshchenko, L. G., Henrikson, C. A., Sotoodehnia, N., Arking, D. E., Agarwal, S. K., Siscovick, D. S., Post, W. S., Solomon, S. D., Coresh, J., Josephson, M. E., Soliman, E. Z. Tags: Coronary Heart Disease Source Type: research

Peripheral Arterial Disease and Risk of Atrial Fibrillation and Stroke: The Multi-Ethnic Study of Atherosclerosis Coronary Heart Disease
Conclusions PAD is associated with an increased risk of AF and stroke in MESA. Potentially, the relationship between PAD and stroke is not mediated by AF.
Source: JAHA:Journal of the American Heart Association - November 17, 2014 Category: Cardiology Authors: O'Neal, W. T., Efird, J. T., Nazarian, S., Alonso, A., Heckbert, S. R., Soliman, E. Z. Tags: Coronary Heart Disease Source Type: research

Prognostic Value of Estimated Functional Capacity Incremental to Cardiac Biomarkers in Stable Cardiac Patients Coronary Heart Disease
Conclusion A simple self-assessment tool of functional capacity in stable patients undergoing elective diagnostic cardiac evaluation provides independent and incremental prognostic value for prediction of both significant coronary angiographic disease and long-term adverse clinical events.
Source: JAHA:Journal of the American Heart Association - October 20, 2014 Category: Cardiology Authors: Tang, W. H. W., Topol, E. J., Fan, Y., Wu, Y., Cho, L., Stevenson, C., Ellis, S. G., Hazen, S. L. Tags: Coronary Heart Disease Source Type: research

Importance of Exercise Capacity in Predicting Outcomes and Determining Optimal Timing of Surgery in Significant Primary Mitral Regurgitation Valvular Heart Disease
Conclusion In patients with primary MR that underwent exercise echocardiography followed by MV surgery, lower achieved metabolic equivalents were associated with worse long-term outcomes. In those with preserved exercise capacity, delaying MV surgery by ≥1 year did not adversely affect outcomes.
Source: JAHA:Journal of the American Heart Association - September 11, 2014 Category: Cardiology Authors: Naji, P., Griffin, B. P., Barr, T., Asfahan, F., Gillinov, A. M., Grimm, R. A., Rodriguez, L. L., Mihaljevic, T., Stewart, W. J., Desai, M. Y. Tags: Valvular Heart Disease Source Type: research

B-type Natriuretic Peptides for the Prediction of Cardiovascular Events in Patients With Stable Coronary Heart Disease: The Heart and Soul Study Coronary Heart Disease
Conclusions Both BNP and NT-proBNP were significant predictors of MACE in stable coronary heart disease; however, NT-proBNP was superior to BNP for net risk reclassification for MACE.
Source: JAHA:Journal of the American Heart Association - July 22, 2014 Category: Cardiology Authors: Mishra, R. K., Beatty, A. L., Jaganath, R., Regan, M., Wu, A. H. B., Whooley, M. A. Tags: Coronary Heart Disease Source Type: research

Reduction in Overall Occurrences of Ischemic Events With Vorapaxar: Results From TRACER Coronary Heart Disease
Conclusions Vorapaxar reduced overall occurrences of ischemic events, but increased bleeding. These exploratory findings broaden our understanding of vorapaxar's potential and expand our understanding of the value of capturing recurrent events. Clinical Trial Registration URL: ClinicalTrials.gov. Unique identifier: NCT00527943.
Source: JAHA:Journal of the American Heart Association - July 10, 2014 Category: Cardiology Authors: White, H. D., Huang, Z., Tricoci, P., Van de Werf, F., Wallentin, L., Lokhnygina, Y., Moliterno, D. J., Aylward, P. E., Mahaffey, K. W., Armstrong, P. W. Tags: Coronary Heart Disease Source Type: research

Associations of Stressful Life Events and Social Strain With Incident Cardiovascular Disease in the Women's Health Initiative Epidemiology
Conclusions Higher SLE and social strain were associated with higher incident CVD independent of sociodemographic factors and depressive symptoms, but not behavioral and biological risk factors.
Source: JAHA:Journal of the American Heart Association - June 27, 2014 Category: Cardiology Authors: Kershaw, K. N., Brenes, G. A., Charles, L. E., Coday, M., Daviglus, M. L., Denburg, N. L., Kroenke, C. H., Safford, M. M., Savla, T., Tindle, H. A., Tinker, L. F., Van Horn, L. Tags: Epidemiology Source Type: research

Haptoglobin 2-2 Genotype is Not Associated With Cardiovascular Risk in Subjects With Elevated Glycohemoglobin--Results From the Bruneck Study Genetics
Conclusions Subjects with the Hp 2-2 genotype and elevated HbA1c compared with subjects with other Hp genotypes and elevated HbA1c did not show increased CVD risk.
Source: JAHA:Journal of the American Heart Association - May 16, 2014 Category: Cardiology Authors: Pechlaner, R., Kiechl, S., Willeit, P., Demetz, E., Haun, M., Weger, S., Oberhollenzer, F., Kronenberg, F., Bonora, E., Weiss, G., Willeit, J. Tags: Genetics Source Type: research

Long-term Cardiovascular Risks Associated With an Elevated Heart Rate: The Framingham Heart Study Epidemiology
Conclusions Individuals with a higher heart rate are at elevated long-term risk for cardiovascular events, in particular, heart failure, and all-cause death. On the other hand, a higher heart rate is associated with a lower risk of future permanent pacemaker implantation.
Source: JAHA:Journal of the American Heart Association - May 8, 2014 Category: Cardiology Authors: Ho, J. E., Larson, M. G., Ghorbani, A., Cheng, S., Coglianese, E. E., Vasan, R. S., Wang, T. J. Tags: Epidemiology Source Type: research

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