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Source: Hypertension
Drug: Furosemide

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Abstract 137: Sox6 Regulates Renin Expression During Juxtaglomerular Cell Expansion Session Title: Renin Angiotensin System II
Introduction: Hypertension, a common condition that affects 33% of the US population, is a major risk factor for heart disease and stroke. Treatments for hypertension are limited and there is a critical need to develop new therapies. The Renin Angiotensin Aldosterone System (RAAS) plays a key role in regulating blood pressure, and renin controls its rate-limiting step. In adults, renin is produced and stored by renal Juxtaglomerular (JG) cells. During sodium restriction and other pathophysiological stresses that require an increase in renin expression and release, the adult kidney increases the number of cells expressing r...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Jason D Foss, Liang Xiao, Kandi D Horton, Mohammad Saleem, Conrad P Hodgkinson, David G Harrison, Jose A Gomez Tags: Oral Abstract Presentations Source Type: research