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Incidence and Clinical Impact of Stroke Complicating Percutaneous Coronary Intervention: Results of the Euro Heart Survey Percutaneous Coronary Interventions Registry Cardiac Catheterization
Conclusions— Stroke as complication of PCI occurs rarely (0.4%) in clinical practice in Europe today. However, peri-interventional stroke is still associated with an exceedingly high in-hospital mortality rate. Most predictors for periprocedural stroke are not modifiable and cannot be diminished before PCI. Therefore, treatment of patients with stroke after PCI needs further research.
Source: Circulation: Cardiovascular Interventions - August 20, 2013 Category: Cardiology Authors: Werner, N., Bauer, T., Hochadel, M., Zahn, R., Weidinger, F., Marco, J., Hamm, C., Gitt, A. K., Zeymer, U. Tags: Acute Stroke Syndromes Cardiac Catheterization Source Type: research

Triple Antithrombotic Therapy Is the Independent Predictor for the Occurrence of Major Bleeding Complications: Analysis of Percent Time in Therapeutic Range Pharmacology
Conclusions— Triple antithrombotic therapy predisposes patients to an increased risk of MBC regardless of the time in therapeutic range.
Source: Circulation: Cardiovascular Interventions - August 20, 2013 Category: Cardiology Authors: Naruse, Y., Sato, A., Hoshi, T., Takeyasu, N., Kakefuda, Y., Ishibashi, M., Misaki, M., Abe, D., Aonuma, K., Ibaraki Cardiovascular Assessment Study (ICAS) Registry Tags: Catheter-based coronary interventions: stents Pharmacology Source Type: research

Percutaneous Steerable Robotic Tool Delivery Platform and Metal Microelectromechanical Systems Device for Tissue Manipulation and Approximation: Closure of Patent Foramen Ovale in an Animal Model Congenital Heart Disease
Conclusions— In contrast to existing robotic catheter technologies, the robotic tool delivery platform uses a combination of stiffness and active steerability along its length to provide the positioning accuracy and force-application capability necessary for tissue manipulation. In combination with a microelectromechanical systems tool technology, it can enable reconstructive procedures inside the beating heart.
Source: Circulation: Cardiovascular Interventions - August 20, 2013 Category: Cardiology Authors: Vasilyev, N. V., Gosline, A. H., Butler, E., Lang, N., Codd, P. J., Yamauchi, H., Feins, E. N., Folk, C. R., Cohen, A. L., Chen, R., Zurakowski, D., del Nido, P. J., Dupont, P. E. Tags: Animal models of human disease, Ablation/ICD/surgery, Catheter-based coronary and valvular interventions: other, Pediatric and congenital heart disease, including cardiovascular surgery, Other Stroke Treatment - Surgical Source Type: research

Relationship Between ST-Segment Recovery and Clinical Outcomes After Primary Percutaneous Coronary Intervention: The HORIZONS-AMI ECG Substudy Report Myocardial Infarction
Conclusions— In this large international study, absent STR 60 minutes after primary PCI was present in 1 in 5 patients with ST-segment–elevation myocardial infarction and was a significant independent predictor of major adverse cardiovascular events and target vessel revascularization at 3 years. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00433966
Source: Circulation: Cardiovascular Interventions - June 18, 2013 Category: Cardiology Authors: Farkouh, M. E., Reiffel, J., Dressler, O., Nikolsky, E., Parise, H., Cristea, E., Baran, D. A., Dizon, J., Merab, J. P., Lansky, A. J., Mehran, R., Stone, G. W. Tags: Electrocardiology, Catheter-based coronary interventions: stents, Acute myocardial infarction Source Type: research

Remote Ischemic Preconditioning Improves Outcome at 6 Years After Elective Percutaneous Coronary Intervention: The CRISP Stent Trial Long-term Follow-up Coronary Interventions
Conclusions— Remote ischemic preconditioning reduces the incidence of postprocedural cardiac troponin I after elective PCI and confers an MACCE-free survival benefit at both short- and long-term follow-up. Clinical Trial Registration— URL: http://www.ukcrn.org.uk. Unique identifier: UKCRN 4074
Source: Circulation: Cardiovascular Interventions - June 18, 2013 Category: Cardiology Authors: Davies, W. R., Brown, A. J., Watson, W., McCormick, L. M., West, N. E. J., Dutka, D. P., Hoole, S. P. Tags: Catheter-based coronary interventions: stents Source Type: research

Risk Factors for Cerebral Embolization After Carotid Artery Stenting With Embolic Protection: A Diffusion-Weighted Magnetic Resonance Imaging Study in 837 Consecutive Patients Peripheral Artery Disease
Conclusions— Age, hypertension, lesion morphology, and aortic arch type were predictive for procedural-related cerebral embolic lesions during embolic protected CAS. Age, significant contralateral carotid stenosis, and complex aortic arch type were predictive for bilateral ischemic lesions. The clinical implications of ischemic lesions are not yet fully understood.
Source: Circulation: Cardiovascular Interventions - June 18, 2013 Category: Cardiology Authors: Bijuklic, K., Wandler, A., Varnakov, Y., Tuebler, T., Schofer, J. Tags: Carotid Stenosis, Computerized tomography and Magnetic Resonance Imaging, Angioplasty and Stenting Peripheral Artery Disease Source Type: research

Hemorrhagic and Ischemic Outcomes After Bivalirudin Versus Unfractionated Heparin During Carotid Artery Stenting: A Propensity Score Analysis From the NCDR Peripheral Vascular Disease
Conclusions— Bivalirudin was associated with lower rates of hemorrhagic outcomes compared with UFH during the index hospitalization for carotid artery stenting. In-hospital and 30-day ischemic events were similar between the 2 groups. Randomized comparisons of these agents are needed to confirm these findings.
Source: Circulation: Cardiovascular Interventions - April 16, 2013 Category: Cardiology Authors: Wayangankar, S. A., Abu-Fadel, M. S., Aronow, H. D., Kennedy, K. F., Gupta, R., Yeh, R. W., Gray, W. A., Rosenfield, K., Hennebry, T. A. Tags: Heparin, Other anticoagulants, Carotid Stenosis, Angioplasty and Stenting, Transient Ischemic Attacks Peripheral Vascular Disease Source Type: research

Association of Body Mass Index With Major Cardiovascular Events and With Mortality After Percutaneous Coronary Intervention Coronary Artery Disease
Conclusions— Among patients undergoing percutaneous coronary intervention, a low BMI was associated with increased risks of major cardiovascular events and death. However, there were no excess risks of these events associated with a high BMI.
Source: Circulation: Cardiovascular Interventions - April 16, 2013 Category: Cardiology Authors: Park, D.-W., Kim, Y.-H., Yun, S.-C., Ahn, J.-M., Lee, J.-Y., Kim, W.-J., Kang, S.-J., Lee, S.-W., Lee, C. W., Park, S.-W., Park, S.-J. Tags: Obesity, Catheter-based coronary interventions: stents Coronary Artery Disease Source Type: research

Stroke After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction: Timing, Characteristics, and Clinical Outcomes Coronary Artery Disease
Conclusions— Stroke is an infrequent complication in the setting of ST-segment elevation myocardial infarction treated with primary PCI but is associated with increased morbidity and mortality. Studies to determine mechanisms that may be responsible for strokes that occur >48 hours from primary PCI are warranted. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00091637.
Source: Circulation: Cardiovascular Interventions - April 16, 2013 Category: Cardiology Authors: Guptill, J. T., Mehta, R. H., Armstrong, P. W., Horton, J., Laskowitz, D., James, S., Granger, C. B., Lopes, R. D. Tags: Coronary Artery Disease Source Type: research

Atrial Fibrillation and Aortic Stenosis: Impact on Clinical Outcomes Among Patients Undergoing Transcatheter Aortic Valve Implantation Structural Heart Disease
Conclusions— AF is common among high-risk patients with severe aortic stenosis undergoing transcatheter aortic valve implantation and is associated with a >2-fold increased risk of all-cause and cardiovascular mortality, irrespective of the type of AF. The gradient of risk directly correlates with the CHA2DS2–VASC score.
Source: Circulation: Cardiovascular Interventions - February 19, 2013 Category: Cardiology Authors: Stortecky, S., Buellesfeld, L., Wenaweser, P., Heg, D., Pilgrim, T., Khattab, A. A., Gloekler, S., Huber, C., Nietlispach, F., Meier, B., Juni, P., Windecker, S. Tags: Valvular heart disease, Catheter-based coronary and valvular interventions: other Structural Heart Disease Source Type: research

Procedural Safety and Predictors of Acute Outcome of Intracoronary Administration of Progenitor Cells in 775 Consecutive Procedures Performed for Acute Myocardial Infarction or Chronic Heart Failure Myocardial Infarction
Conclusions— Intracoronary infusion of progenitor cells can be performed with adequate safety in patients with acute myocardial infarction or CHF, because the safety profile was similar to what is usually expected from a coronary angiogram in the present cohort. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00962364, NCT00284713, and NCT00289822.
Source: Circulation: Cardiovascular Interventions - February 19, 2013 Category: Cardiology Authors: De Rosa, S., Seeger, F. H., Honold, J., Fischer-Rasokat, U., Lehmann, R., Fichtlscherer, S., Schachinger, V., Dimmeler, S., Zeiher, A. M., Assmus, B. Tags: Other myocardial biology, Catheter-based coronary and valvular interventions: other Myocardial Infarction Source Type: research

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