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Source: Circulation: Cardiovascular Interventions

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Total 86 results found since Jan 2013.

Lack of Concordance Between Local Investigators, Angiographic Core Laboratory, and Clinical Event Committee in the Assessment of Stent Thrombosis: Results From the TRACER Angiographic Substudy Coronary Interventions
Conclusions— ST reporting by an ACL, a CEC, and LIs is discordant. The assessment of ST is more often detected by direct review of angiograms by an ACL. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00527943.
Source: Circulation: Cardiovascular Interventions - May 8, 2016 Category: Cardiology Authors: Popma, C. J., Sheng, S., Korjian, S., Daaboul, Y., Chi, G., Tricoci, P., Huang, Z., Moliterno, D. J., White, H. D., Van de Werf, F., Harrington, R. A., Wallentin, L., Held, C., Armstrong, P. W., Aylward, P. E., Strony, J., Mahaffey, K. W., Gibson, C. M. Tags: Angiography, Imaging, Percutaneous Coronary Intervention Coronary Interventions Source Type: research

Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Low-Risk Patients Structural Heart Disease
Conclusions— In patients with low operative risk, significantly better 3-year survival and freedom from major adverse cardiac and cerebrovascular events were observed after SAVR compared with TAVI. Further studies on new-generation valve prostheses are necessary before expanding indications of TAVI toward lower-risk patients.
Source: Circulation: Cardiovascular Interventions - May 5, 2016 Category: Cardiology Authors: Rosato, S., Santini, F., Barbanti, M., Biancari, F., DErrigo, P., Onorati, F., Tamburino, C., Ranucci, M., Covello, R. D., Santoro, G., Grossi, C., Ventura, M., Fusco, D., Seccareccia, F., on behalf of the OBSERVANT Research Group Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Mortality/Survival Structural Heart Disease Source Type: research

Left Atrial Appendage and Closure: Who, When, and How Advances in Interventional Cardiology
Patients with nonvalvular atrial fibrillation have a 4- to 5-fold increase in strokes and that rhythm may be responsible for 15% to 20% of all strokes, particularly in the elderly. In this setting, thrombus in the left atrial appendage has been found to be the source of stroke in 90% of cases. Although oral anticoagulants have been found effective in reducing stroke rates, for a variety of issues, they may only be used in 40% to 50% of patients at increased risk for stroke. Given pathophysiology of stroke, site-specific therapy directed at left atrial appendage occlusion has been now studied for stroke prevention, and one ...
Source: Circulation: Cardiovascular Interventions - May 1, 2016 Category: Cardiology Authors: Holmes, D. R., Reddy, V. Y. Tags: Treatment Advances in Interventional Cardiology Source Type: research

Outcomes Following Primary Percutaneous Coronary Intervention in Patients With Previous Coronary Artery Bypass Surgery Coronary Interventions
Conclusions— A prior history of CABG in patients presenting with STEMI and undergoing PPCI does not independently confer additional risk of mortality, although it is a marker of other high-risk features.
Source: Circulation: Cardiovascular Interventions - April 10, 2016 Category: Cardiology Authors: Iqbal, J., Kwok, C. S., Kontopantelis, E., de Belder, M. A., Ludman, P. F., Giannoudi, M., Gunning, M., Zaman, A., Mamas, M. A., on behalf of the British Cardiovascular Intervention Society (BCIS) and the National Institute for Cardiovascular Outcomes Res Tags: Catheter-Based Coronary and Valvular Interventions, Percutaneous Coronary Intervention Coronary Interventions Source Type: research

Embolic Protection Devices in Transcatheter Aortic Valve Replacement Contemporary Reviews in Interventional Cardiology
The initially reported periprocedural neurological events rates associated with transcatheter aortic valve replacement raised concerns that ultimately led to the development and to the clinical research of novel embolic protection devices. Although the reduction of clinical stroke is a desired goal, the current research design of embolic protection devices focuses on surrogate markers of the clinical disease, primarily on silent central nervous system lesions observed in postprocedural diffuse-weighted magnetic resonance imaging and cognitive function testing. As the mere presence of particulate debris in brain matter may ...
Source: Circulation: Cardiovascular Interventions - March 7, 2016 Category: Cardiology Authors: Steinvil, A., Benson, R. T., Waksman, R. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Catheter-Based Coronary and Valvular Interventions, Cerebrovascular Disease/Stroke, Cognitive Impairment Contemporary Reviews in Interventional Cardiology Source Type: research

Six Versus 12 Months of Dual Antiplatelet Therapy After Implantation of Biodegradable Polymer Sirolimus-Eluting Stent: Randomized Substudy of the I-LOVE-IT 2 Trial Coronary Interventions
Conclusions— This study indicated noninferiority in safety and efficacy of 6-month versus 12-month DAPT after implantation of a novel biodegradable polymer sirolimus-eluting stent. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01681381.
Source: Circulation: Cardiovascular Interventions - February 8, 2016 Category: Cardiology Authors: Han, Y., Xu, B., Xu, K., Guan, C., Jing, Q., Zheng, Q., Li, X., Zhao, X., Wang, H., Zhao, X., Li, X., Yu, P., Zang, H., Wang, Z., Cao, X., Zhang, J., Pang, W., Li, J., Yang, Y., Dangas, G. D. Tags: Catheter-Based Coronary and Valvular Interventions Coronary Interventions Source Type: research

Clopidogrel Versus Aspirin as an Antiplatelet Monotherapy After 12-Month Dual-Antiplatelet Therapy in the Era of Drug-Eluting Stents Pharmacology
Conclusions— After 12-month DAPT, clopidogrel monotherapy, when compared with aspirin monotherapy, might be associated with a reduced risk of recurrent ischemic events in patients receiving DES.
Source: Circulation: Cardiovascular Interventions - January 11, 2016 Category: Cardiology Authors: Park, T. K., Song, Y. B., Ahn, J., Carriere, K. C., Hahn, J.-Y., Yang, J. H., Choi, S.-H., Choi, J.-H., Lee, S. H., Gwon, H.-C. Tags: Anticoagulants, Percutaneous Coronary Intervention, Stent Pharmacology Source Type: research

Bivalirudin Is Associated With Improved In-Hospital Outcomes Compared With Heparin in Percutaneous Vascular Interventions: Observational, Propensity-Matched Analysis From the Premier Hospital Database Peripheral Vascular Disease
Conclusions— In patients undergoing peripheral vascular interventions, procedural anticoagulation with bivalirudin may result in more favorable in-hospital outcomes compared with unfractionated heparin, the current standard of care. These observations will require prospective confirmation in a randomized, controlled trial.
Source: Circulation: Cardiovascular Interventions - January 8, 2016 Category: Cardiology Authors: Kimmelstiel, C., Pinto, D., Aronow, H. D., Weintraub, A. R., Dangas, G., Fan, W., Prats, J., Deliargyris, E. N., Katzen, B. T. Tags: Anticoagulants, Pharmacology, Peripheral Vascular Disease, Vascular Disease Source Type: research

Procedural Results and Clinical Outcomes of Transcatheter Aortic Valve Implantation in Switzerland: An Observational Cohort Study of Sapien 3 Versus Sapien XT Transcatheter Heart Valves Structural Heart Disease
Conclusions— The use of the new generation S3 balloon-expandable THV reduced the risk of more than mild paravalvular regurgitation and vascular complications but was associated with an increased permanent pacemaker rate compared with the XT. Transcatheter aortic valve implantation using the newest generation balloon-expandable THV is associated with a low risk of stroke and favorable clinical outcomes. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01368250.
Source: Circulation: Cardiovascular Interventions - October 9, 2015 Category: Cardiology Authors: Binder, R. K., Stortecky, S., Heg, D., Tueller, D., Jeger, R., Toggweiler, S., Pedrazzini, G., Amann, F. W., Ferrari, E., Noble, S., Nietlispach, F., Maisano, F., Raber, L., Roffi, M., Grunenfelder, J., Juni, P., Huber, C., Windecker, S., Wenaweser, P. Tags: Catheter-based coronary and valvular interventions: other, CV surgery: valvular disease Structural Heart Disease Source Type: research

Is Aspiration Thrombectomy Beneficial in Patients Undergoing Primary Percutaneous Coronary Intervention?: Meta-Analysis of Randomized Trials Myocardial Infarction
Conclusions— Aspiration thrombectomy before primary PCI is not associated with any benefit on clinical end points and might increase the risk of stroke. Concomitant administration of intravenous glycoprotein IIb/IIIa inhibitors and ischemic time did not seem to influence any potential benefits observed with aspiration thrombectomy.
Source: Circulation: Cardiovascular Interventions - July 14, 2015 Category: Cardiology Authors: Elgendy, I. Y., Huo, T., Bhatt, D. L., Bavry, A. A. Tags: Other Treatment Myocardial Infarction Source Type: research

Everolimus Eluting Stents Versus Coronary Artery Bypass Graft Surgery for Patients With Diabetes Mellitus and Multivessel Disease Coronary Artery Disease
Conclusions— In patients with diabetes mellitus and multivessel disease, EES was associated with lower upfront risk of death and stroke when compared with coronary artery bypass graft surgery. However, at long-term, EES was associated with similar risk of death, a higher risk of MI (in those with incomplete revascularization), and repeat revascularization but a lower risk of stroke.
Source: Circulation: Cardiovascular Interventions - July 8, 2015 Category: Cardiology Authors: Bangalore, S., Guo, Y., Samadashvili, Z., Blecker, S., Xu, J., Hannan, E. L. Tags: Type 2 diabetes, Catheter-based coronary interventions: stents, CV surgery: coronary artery disease, Chronic ischemic heart disease Source Type: research

Impact of Arterial Access Site on Outcomes After Primary Percutaneous Coronary Intervention: Prespecified Subgroup Analysis From the EUROMAX Trial Coronary Interventions
Conclusions— In this prespecified analysis from EUROMAX, radial access was preferred in lower risk patients and did not improve clinical outcomes. Bivalirudin was associated with less bleeding irrespective of access site. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01087723.
Source: Circulation: Cardiovascular Interventions - June 8, 2015 Category: Cardiology Authors: Hamon, M., Coste, P., van't Hof, A., Ten Berg, J., Clemmensen, P., Tabone, X., Benamer, H., Kristensen, S. D., Cavallini, C., Marzocchi, A., Hamm, C., Kanic, V., Bernstein, D., Anthopoulos, P., Deliargyris, E. N., Steg, P. G. Tags: Cardiovascular Pharmacology, Catheter-based coronary and valvular interventions: other, Acute myocardial infarction Coronary Interventions Source Type: research

Transcatheter Aortic Valve Replacement and Stroke Editor's Perspective
Source: Circulation: Cardiovascular Interventions - June 4, 2015 Category: Cardiology Authors: Wimmer, N. J., Williams, D. O. Tags: Catheter-based coronary and valvular interventions: other, Other Stroke Treatment - Surgical Editor ' s Perspective Source Type: research

High Event Rate After a First Percutaneous Coronary Intervention in Patients With Diabetes Mellitus: Results From the Swedish Coronary Angiography and Angioplasty Registry Coronary Interventions
Conclusions— The prognosis after a first percutaneous coronary intervention is more severe in patients with diabetes mellitus, in particular, in patients treated with insulin, with higher rates of mortality, cardiovascular events, and stent thrombosis over the following 5 years.
Source: Circulation: Cardiovascular Interventions - May 29, 2015 Category: Cardiology Authors: Ritsinger, V., Saleh, N., Lagerqvist, B., Norhammar, A. Tags: Type 2 diabetes, Catheter-based coronary interventions: stents Source Type: research

Surgical Versus Percutaneous Coronary Revascularization for Multivessel Disease in Diabetic Patients With Non-ST-Segment-Elevation Acute Coronary Syndrome: Analysis From the Acute Catheterization and Early Intervention Triage Strategy Trial Coronary Artery Disease
Conclusions— In the large-scale ACUITY trial, diabetic patients with acute coronary syndrome and multivessel disease treated with PCI rather than CABG had less bleeding and acute kidney injury, greater need for repeat revascularization procedures, and comparable rates of myocardial infarction, stroke, and death through 1-year follow-up. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00093158.
Source: Circulation: Cardiovascular Interventions - May 27, 2015 Category: Cardiology Authors: Ben-Gal, Y., Mohr, R., Feit, F., Ohman, E. M., Kirtane, A., Xu, K., Mehran, R., Stone, G. W. Tags: Other diabetes, Catheter-based coronary interventions: stents, CV surgery: coronary artery disease Source Type: research