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Source: The Journal of Heart and Lung Transplantation
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Total 77 results found since Jan 2013.

Detection of inflow obstruction in left ventricular assist devices by accelerometer: A porcine model study
Left ventricular assist devices (LVAD) provide circulatory blood pump support for severe heart failure patients. Pump inflow obstructions may lead to stroke and pump malfunction. We aimed to verify in vivo that gradual inflow obstructions, representing prepump thrombosis, are detectable by a pump-attached accelerometer, where the routine use of pump power (PLVAD) is deficient.
Source: The Journal of Heart and Lung Transplantation - April 4, 2023 Category: Transplant Surgery Authors: Didrik Lilja, Itai Schalit, Andreas Espinoza, Arnt Eltvedt Fiane, Gry Dahle, Helen Littorin-Sandbu, Fred-Johan Pettersen, Kristoffer Engh Russell, Amrit Paul Singh Thiara, Ole Jakob Elle, Per Steinar Halvorsen Tags: Original Pre-Clinical Science Source Type: research

Platelet Function and Sildenafil Use During Left Ventricular Assist Device Support
Clinical outcome studies have shown that sildenafil is associated with reduced mortality and thrombotic events such as ischemic stroke during contemporary left ventricular assist device (LVAD) support. Sildenafil has anti-platelet properties but its relation to platelet function during LVAD support is uncertain.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: O. Saeed, M. Farooq, T. Chinnadurai, J. Ramos, S. Patel, P. Chavez, Y. Rochlani, S. Murthy, J. Shin, S. Vukelic, D. Sims, D. Goldstein, U. Jorde Tags: (136) Source Type: research

A Retrospective Study on Gender, LAA Morphology and Stroke Risk
This was a retrospective study to investigate whether gender and LAA size/morphology was a predictor of cerebral vascular events in patients undergoing cardiac surgery. We studied the LAA morphology, and measurements for women and men in an attempt to correlate the different morphologies/sizes with the patient's risk of stroke.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: K. Sorensen, D. Rodgers, S. Chandra Uppalapati, U. Siddiqi, S. Jain, S. Paluri, A. Madhushanka, K. Sudheendra, K. Johnson, S. Bangaru, K. Ram, D. Hynes, C. Ozcan, L. Lee, G. Kim, V. Jeevanandam Tags: (550) Source Type: research

Estimation of Stroke Risk in Patients with Fabry Disease Using a Machine Learning Model
In this study, the performance of a machine learning platform in estimating FD patients’ 12-month stroke risk was assessed.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: J. Jefferies, S. Kallish, G. Biondetti, P. Aguiar, M. Nelson, J. Giuliano, J. Zabinksi, C. Boussios, G. Curhan, J. Bandaria, R. Gliklich, D. Warnock Tags: (753) Source Type: research

Comparing Velocity and Mean Arterial Pressure to Assess Pulsatility in Patients with Continuous Flow Left Ventricular Assist Devices
An increasing number of end-stage heart failure patients are supported by continuous-flow Left Ventricular Assist Devices (cfLVADs). In these patients, accurate assessment of arterial pulsatility remains a challenge because of diminished pulse pressure. Limited pulsatility in modern cfLVADs itself can be associated with adverse events such as stroke. Our study investigates the value of simultaneous arterial pressure and arterial blood velocity assessment in cfLVAD patients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: S. Emmanuel, A. Adji, P. Jansz, C. Hayward Tags: (871) Source Type: research

Computational Investigation of Outflow Graft Variation Impact on Hemocompatibility Profile in LVADs
This study, used a simulation-based approach to investigate the influence that the cannula orientation has in modulating flow conditions leading to HRAEs.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: B.A. Zambrano, S. Ingram, M.R. Moreno, M. Kassi Tags: (1161) Source Type: research

Increased Nocturnal Arterial Stiffness is Associated with a Higher Risk of Stroke in LVAD Patients
In this study, we aimed to investigate whether increased arterial stiffness is associated with a higher risk of stroke in LVAD patients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: F. Castagna, G.M. Mondellini, B. McDonnell, A. Pinsino, M. Tiburcio, M. Pineda, K. Takeda, Y. Naka, A. Ladanyi, G.T. Sayer, N. Uriel, M. Yuzefpolskaya, J.Z. Willey, G. Parati, J. Cockcroft, P.C. Colombo Tags: (1148) Source Type: research

Optimization of Left Ventricle Size After VAD Implantation Prevents Incidence of Cerebral Infarction
Stroke after ventricular assist device (VAD) implantation is a critical complication. Previous studies have noted the distance between the inflow cannula and the left ventricular (LV) septum, as well as an angulation of the inflow cannula from the apical axis, related to the incidence of stroke. In the early phase after VAD implantation, diuresis is caused by improved renal blood flow, furthermore, rapid volume reduction of LV greatly changes circulating plasma volume, resulting in increased stroke risk; however, little is known about an appropriate indicator for the prevention of this phenomenon.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: R. Ikeda, Y. Ichihara, Y. Yamada, S. Saito, T. Nishinaka, T. Shinkawa, H. Niinami Tags: (1142) Source Type: research

Stroke and Pump Thrombosis Following LVAD Implantation: The Impact of the Implantation Approach
The aim of this study is to investigate the impact of LVAD (left ventricular assist device) implantation technique on long-term mortality and morbidity, with special focus on stroke and pump thrombosis.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: M. Nozdrzykowski Tags: (650) Source Type: research

Postoperative Atrial Fibrillation in Lung Transplant Recipients with and without Concomitant Modified Maze
Atrial fibrillation is common following lung transplantation and may contribute to increased risk of stroke. The goal of this study was to characterize the incidence of atrial fibrillation in lung transplant recipients with and without a concomitant modified Maze procedure.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: Y. Xia, S. Patel, S. Lee, R. Villamater, R. Biniwale, A. Ardehali Tags: (633) Source Type: research

Protein Biomarkers Predict Risk of Gastrointestinal Bleeding in Left Ventricular Assist Device Patients
This study aims to assess the validity of these biomarkers in predicting the incidence of stroke or GIB in LVAD recipients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: K. Cavallo, M. Kanwar, G. Diao, S.S. Sinha, R. Singh, D. Tang, I. Isseh, J. Brocious, P. Bagchi, D. Crandall, D.J. Farrar, S. Murali, J. Walenga, J. Lindenfeld, C. deFilippi, P. Shah Tags: (115) Source Type: research

Who is at Risk for Seizures After Heart Transplantation?
Seizures may occur following heart transplantation (HTx), especially since tacrolimus can lower a seizure threshold. HTx recipients are also at high stroke risk given many patients have existing cerebrovascular disease. The purpose of the study was to assess the prevalence and risk factors for seizures in HTx recipients at our center.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: M. Kittleson, J. Patel, D. Chang, T. Singer-Englar, N. Patel, L. Mishalani, S. Kim, D. Ramzy, L. Czer, J.A. Kobashigawa Tags: (776) Source Type: research

Reservoir Pressure Analysis in Group 2 Pulmonary Hypertension
In this study we aim to describe Pres in Group 2 isolated post-capillary (IPC) and combined pre and post-capillary (CPC) pulmonary hypertension (PH).
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: I. Yim, K. Parker, S. Lim Tags: (307) Source Type: research

Central VA-ECMO Support without Full Anticoagulation is Feasible During Lung Transplant
In this study, we analyzed the feasibility of central VA-ECMO without full anticoagulation during lung transplantation. We also analyzed the incidence of morbidity including ischemic and thrombotic complications, stroke, and postoperative outcomes.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: Y. Yagi, A. Manerikar, A. Bharat, C. Kurihara Tags: (911) Source Type: research

Assessing Cardiac Recovery for Decommissioning of LVAD Support: Structure versus Function
Recovery of left ventricular (LV) function during LVAD support occurs in only 1-3% of patients. Assessment for recovery and LVAD removal is desirable given the risks of infection, stroke, and device malfunction. This case of a patient with an LVAD, with recovered LV systolic function but abnormal exercise hemodynamics, illustrates the potential utility of right heart catheterization studies for clinical decisions.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: R.S. Gabarin, V. Gurtu, D.H. Brahmbhatt, F. Billia, S. Mak Tags: (550) Source Type: research