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Computed tomography versus short sequence magnetic resonance imaging in acute ischaemic stroke
It is undisputable that the acute management of stroke requires a fast and accurate diagnostic imaging modality. We read with interest and congratulate Kumar et al. on their article discussing the superiority and benefits of the use of magnetic resonance imaging (MRI) in acute ischaemic stroke (AIS) [1]. The authors suggest that MRI can improve the diagnostic accuracy of computed tomography (CT) negative AIS and allow better selection of patients for reperfusion therapies. Moreover, MRI may help avoid hospital admissions for patients with stroke mimics, facilitate earlier discharge, reduce overall hospital costs and play a...
Source: Journal of the Neurological Sciences - March 30, 2023 Category: Neurology Authors: Ho Lun Wong, Ashraf Nasim, Amit K.J. Mandal, Robert Davies, Constantinos G. Missouris Source Type: research

Restricted access in the emergency department prevents MRI from being the workhorse for ischemic stroke care
We express our sincere gratitude to Wong et al. for their interest in our recent publication, “Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?” [1]. We value the insights provided by the authors regarding the potential of magnetic resonance imaging (MRI) as the preferred imaging modality for acute ischemic stroke (AIS). Additionally, we appre ciate their valuable contribution on the utilization of short-sequence head MRI in addition to computed tomography (CT) for AIS evaluation at their center, which provides further evidence for the use of MRI in this context.
Source: Journal of the Neurological Sciences - March 26, 2023 Category: Neurology Authors: Mukesh Kumar, Sherry Hu, Steven Beyea, Noreen Kamal Source Type: research

Color-coded multiphase computed tomography angiography may predict outcome in anterior circulation acute ischemic stroke
To evaluate whether arterial and venous color-coded mCTA score may predict clinical outcome in anterior circulation acute ischemic stroke.
Source: Journal of the Neurological Sciences - September 15, 2021 Category: Neurology Authors: Fabio Pilato, Tommaso Verdolotti, Rosalinda Calandrelli, Iacopo Valente, Edoardo Monelli, Simone Cottonaro, Fioravante Capone, Francesco Motolese, Gianmarco Iaccarino, Sergio Soeren Rossi, Cesare Colosimo, Vincenzo Di Lazzaro Source Type: research

Hyperdense middle cerebral artery sign and response to combination of mechanical Thrombectomy plus intravenous thrombolysis in acute stroke patients
Combining intra-arterial mechanical thrombectomy (IAMT) and intravenous thrombolysis (IVT) has shown to have an excellent recanalization rate and better clinical outcome in acute ischemic stroke (AIS) patients. Hyperdense middle cerebral artery sign (HMCAS) on pretreatment non-contrast head CT scan of AIS patients is one of the early ischemic radiological findings in middle cerebral artery territory AIS. We aimed to evaluate whether the presence of HMCAS predicts the outcome of AIS patients receiving combination therapy with IAMT and IVT.
Source: Journal of the Neurological Sciences - August 16, 2021 Category: Neurology Authors: Ashkan Mowla, Seyed-Mostafa Razavi, Navdeep S. Lail, Pegah Mohammadi, Peyman Shirani, Katelyn S. Kavak, Robert N. Sawyer, Haris Kamal Source Type: research

Comparison of automated infarct core volume measures between non-contrast computed tomography and perfusion imaging in acute stroke code patients evaluated for potential endovascular treatment
Patients with small core infarction and salvageable penumbra are likely to benefit from endovascular treatment (EVT). As computed tomography perfusion imaging (CTP) is not always available 24/7 for patient selection, many patients are transferred to stroke centers for CTP. We compared automatically measured infarct core volume (NCCTcore) from the non-contrast computed tomography (NCCT) with ischemic core volume (CTPcore) from CTP and the outcome of EVT to clarify if NCCTcore measurement alone is sufficient to identify patients that benefit from transfer to stroke centers for EVT.
Source: Journal of the Neurological Sciences - May 8, 2021 Category: Neurology Authors: Olli P. Suomalainen, Ahmed Abou Elseoud, Nicolas Martinez-Majander, Marjaana Tiainen, Nina Forss, Sami Curtze Source Type: research

Assessment of vertical component of gaze deviation in acute PICA occlusion on Computed Tomography
In our recent article “Radiological Horizontal Gaze Deviation in the Setting of Acute PICA Territory Ischemia: A Potential Mimic of Large Vessel Occlusion”, we raised the possibility that the horizontal gaze deviation (HGD) seen in PICA stroke patients may be one component of rotational nystagmus [1]. PICA occlusion could result in vermis ischemia and thus, lead to disruption of pathway involving the deep cerebellar nuclei and stimulate fastigial neurons that is responsible saccade generation may fire result in oblique vertical saccades [2–4].
Source: Journal of the Neurological Sciences - March 24, 2021 Category: Neurology Authors: Nan N. Jiang, Wei Wu Source Type: research

Letter to the editor or commentary: Assessment of vertical component of gaze deviation in acute PICA occlusion on Computed Tomography
In our recent article “Radiological Horizontal Gaze Deviation in the Setting of Acute PICA Territory Ischemia: A Potential Mimic of Large Vessel Occlusion”, we raised the possibility that the horizontal gaze deviation (HGD) seen in PICA stroke patients may be one component of rotational nystagmus [1]. PICA occlusion could result in vermis ischemia and thus, lead to disruption of pathway involving the deep cerebellar nuclei and stimulate fastigial neurons that is responsible saccade generation may fire result in oblique vertical saccades [2–4].
Source: Journal of the Neurological Sciences - March 24, 2021 Category: Neurology Authors: Nan N. Jiang, Wei Wu Source Type: research

Differentiation of seizure from stroke using advanced imaging in the acute period
Imaging modalities such as dynamic computed tomography (CT) studies of the brain have aided in clinical management of stroke patients through identification of tissue at risk and tissue infarcted. Such a capability provides the opportunity to intervene in stroke patients previously deemed unfit for thrombectomy, [1] while allowing software engineers to develop modeling tools stratifying the risk and benefit of intervention [2]. One unexpected consequence of these advances is the ability to recognize the neurophysiologic changes associated with stroke mimics such as seizure.
Source: Journal of the Neurological Sciences - August 31, 2020 Category: Neurology Authors: Merritt W. Brown Tags: Letter to the Editor Source Type: research

Left thalamus infarction in the thalamotuberal artery perfusion area causing subcortical diaschisis and transcortical sensory aphasia
The thalamus is related to language function, and some thalamic stroke cases can cause aphasia [1]. However, most previous cases reporting thalamic damage-induced ipsilateral subcortical diaschisis and aphasia were hemorrhagic stroke [1,2]. Only a few left thalamus infarction cases showed cortical hypoperfusion concerned with the aphasia, but no single-photon emission computed tomography (SPECT) or thalamic nucleus data were available [3]. Thus, aphasia pathology due to cortical hypoperfusion following thalamus infarction, especially with respect to thalamic nuclei, is still unknown.
Source: Journal of the Neurological Sciences - January 24, 2020 Category: Neurology Authors: Kosuke Matsuzono, Kohei Furuya, Azusa Karube, Akie Horikiri, Tadashi Ozawa, Takafumi Mashiko, Haruo Shimazaki, Reiji Koide, Ryota Tanaka, Shigeru Fujimoto Tags: Letter to the Editor Source Type: research

Crossed cerebellar diaschisis in Creutzfeldt-Jakob disease evaluated through single photon emission computed tomography
Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common form of human prion disease; it is characterized as a transmissible spongiform encephalopathy. Previously, only two case reports have discussed crossed cerebellar diaschisis (CCD) and sCJD. Herein, we detected CCD in five patients with sCJD and four patients with genetic CJD through SPECT. The combined data of the nine patients further supported CCD when analyzed by 3D-SSP. CCD can occur in several disorders, including, stroke, epilepsy, and encephalitis.
Source: Journal of the Neurological Sciences - September 24, 2018 Category: Neurology Authors: Kenya Nishioka, Michimasa Suzuki, Katsuya Satoh, Nobutaka Hattori Tags: Letter to the Editor Source Type: research

Estimating the uptake of brain imaging and 30-days stroke mortality in Nigeria: A meta-analysis of hospital-based studies
This study aims to estimate the computed tomography (CT) and Magnetic resonance imaging (MRI) uptake, stroke subtypes and 30-days case-fatality in Nigeria.
Source: Journal of the Neurological Sciences - August 23, 2018 Category: Neurology Authors: Martinsixtus Ezejimofor, Amabetare Biu, Olalekan A. Uthman Tags: Review Article Source Type: research

MRI scout images can detect the acute intracerebral hemorrhage on CT
We examined whether MRI scout imaging can detect ICHs observed by computed tomography (CT).
Source: Journal of the Neurological Sciences - February 3, 2018 Category: Neurology Authors: Toshiyuki Hayashi, Junya Aoki, Kentaro Suzuki, Yuki Sakamoto, Satoshi Suda, Seiji Okubo, Masahiro Mishina, Kazumi Kimura Source Type: research

Association between leukoaraiosis and hemorrhagic transformation after cardioembolic stroke due to atrial fibrillation and/or rheumatic heart disease
Cardioembolic stroke due to atrial fibrillation (AF) and/or rheumatic heart disease (RHD) often involves hemorrhagic transformation (HT), and we examined whether leukoaraiosis (LA) was associated with HT in these cases. We prospectively enrolled 251 patients who were admitted to two hospitals within one month of experiencing cardioembolic stroke due to AF/RHD. LA severity was assessed using three visual rating scales. HT was identified in 99 patients (39.4%) based on baseline computed tomography (CT) and post-admission magnetic resonance imaging or second CT.
Source: Journal of the Neurological Sciences - May 2, 2017 Category: Neurology Authors: Chen-Chen Wei, Shu-Ting Zhang, Yun-Han Wang, Jun-Feng Liu, Jie Li, Ruo-Zhen Yuan, Ge Tan, Shi-Hong Zhang, Ming Liu Source Type: research

Orolingual angioedema after thrombolysis is not associated with insular cortex ischemia on pre-thrombolysis CT
Objective: Orolingual angioedema (OA) is a well known early complication of treatment with alteplase in ischemic stroke patients. Our aim was to study risk factors for OA in these patients, namely insular cortex ischemia.Methods: Retrospective case-cohort study using the prospective registry of all consecutive ischemic stroke patients submitted to intravenous thrombolysis with alteplase. Clinical data was retrieved from the registry and medical records. Two independent observers evaluated early signs of insular cortex ischemia on pre-thrombolysis computed tomography (CT) and of insular cortex infarct on early follow-up imaging.
Source: Journal of the Neurological Sciences - July 18, 2016 Category: Neurology Authors: Jo ão Pinho, José Nuno Alves, Liliana Oliveira, Sara Pereira, Joana Barros, Célia Machado, José Manuel Amorim, Ana Filipa Santos, Manuel Ribeiro, Carla Ferreira Source Type: research

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