Orolingual angioedema after thrombolysis is not associated with insular cortex ischemia on pre-thrombolysis CT
Objective: Orolingual angioedema (OA) is a well known early complication of treatment with alteplase in ischemic stroke patients. Our aim was to study risk factors for OA in these patients, namely insular cortex ischemia.Methods: Retrospective case-cohort study using the prospective registry of all consecutive ischemic stroke patients submitted to intravenous thrombolysis with alteplase. Clinical data was retrieved from the registry and medical records. Two independent observers evaluated early signs of insular cortex ischemia on pre-thrombolysis computed tomography (CT) and of insular cortex infarct on early follow-up imaging.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Jo ão Pinho, José Nuno Alves, Liliana Oliveira, Sara Pereira, Joana Barros, Célia Machado, José Manuel Amorim, Ana Filipa Santos, Manuel Ribeiro, Carla Ferreira Source Type: research