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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 6824 results found since Jan 2013.
Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2
Ischemic stroke is a frequently occurring cerebrovascular disease (CVD) linked to high mortality, disability, and incidence rates, and the second factor causing global mortality41,3. There are two common sources of embolism in ischamic strokes: large artery atherosclerosis and small artery atherosclerosis. Ischemic stroke can be treated clinically with thrombolytic therapy4. Although ischemic stroke is treatable, post-cerebral ischemia blood reperfusion frequently induces inflammation, oxidative stress (OS) or additional unfavorable events that may exacerbate brain injury20,24.
Source: Journal of Stroke and Cerebrovascular Diseases - June 30, 2023 Category: Neurology Authors: Yingju Wang, Hongping Chen, Xuehui Fan, Chen Xu, Meng Li, Hongxue Sun, Jihe Song, Feihong Jia, Wan Wei, Fangchao Jiang, Guozhong Li, Di Zhong Source Type: research
Ischemic cerebrovascular complications with initial presentation of genetic atypical hemolytic uremic syndrome
Atypical hemolytic uremic syndrome (aHUS) is a rare disease, with scarce reports of neurologic manifestations in the acute setting. Ischemic cortical infarcts concurrently with aHUS presentation have not been described in adult patients.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2023 Category: Neurology Authors: Maria Sokola, Karlo Toljan, Allaa Almoushref, Zeshaun Khawaja, Tarek Ashour Tags: Case Report Source Type: research
Association between remnant cholesterol and subclinical carotid atherosclerosis among Chinese general population in health examination
Remnant cholesterol (RC) was associated with carotid atherosclerosis in patients with clinical settings. But the value of RC as a risk management indicator for subclinical carotid atherosclerosis in health examination has not been fully determined.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2023 Category: Neurology Authors: Nimei Zeng, Yu'e Shen, Yuan Li, Yun Wang Source Type: research
The clinical utility of dual-energy CT in post-thrombectomy care: Part 1, predictors and outcomes of subarachnoid and intraparenchymal hemorrhage
Dual-energy CT allows differentiation between blood and iodinated contrast. We aimed to determine predictors of subarachnoid and intraparenchymal hemorrhage on dual-energy CT performed immediately post-thrombectomy and the impact of these hemorrhages on 90-day outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2023 Category: Neurology Authors: Seoiyoung Ahn, Nishit Mummareddy, Steven G. Roth, Jacob Jo, Akshay Bhamidipati, Yeji Ko, Julie DiNitto, Rohan V. Chitale, Matthew R. Fusco, Michael T. Froehler Source Type: research
The clinical utility of dual-energy CT in post-thrombectomy care: Part 2, the predictive value of contrast density and volume for delayed hemorrhagic transformation
This study aims to determine the predictive value of contrast density and volume on post-thrombectomy dual-energy CT for delayed hemorrhagic transformation and its impact on 90-day outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2023 Category: Neurology Authors: Seoiyoung Ahn, Steven G. Roth, Nishit Mummareddy, Yeji Ko, Akshay Bhamidipati, Jacob Jo, Julie DiNitto, Matthew R. Fusco, Rohan V. Chitale, Michael T. Froehler Source Type: research
Hyperperfusion syndrome after superficial temporal artery-middle cerebral artery bypass for non-moyamoya steno-occlusive disease
Stroke is a major cause of morbidity and mortality worldwide, and intracranial stenoses increase the risk for stroke. Superficial temporal artery to middle cerebral artery bypass can be beneficial in selected patients with non-moyamoya steno-occlusive disease, however data is limited regarding the postoperative occurrence of hyperperfusion syndrome in this population. This case series describes the outcomes and complications, including hyperperfusion, in these patients who underwent bypass.
Source: Journal of Stroke and Cerebrovascular Diseases - June 27, 2023 Category: Neurology Authors: Justin Turpin, Daniel G. Lynch, Timothy White, Kevin A. Shah, Kaiyun Yang, Jeffrey M. Katz, Amir R. Dehdashti Source Type: research
Cohort profile: The South London Stroke Register – a population-based register measuring the incidence and outcomes of stroke
The South London Stroke Register (SLSR) is a population-based cohort study, which was established in 1995 to study the causes, incidence, and outcomes of stroke. The SLSR aims to estimate incidence, and acute and long term needs in a multi-ethnic inner-city population, with follow-up durations for some participants exceeding 20 years.
Source: Journal of Stroke and Cerebrovascular Diseases - June 27, 2023 Category: Neurology Authors: Iain J Marshall, Charles Wolfe, Eva Emmett, Hatem Wafa, Yanzhong Wang, Abdel Douiri, Ajay Bhalla, Matthew DL O'Connell Source Type: research
Analysis of carotid plaque risk factors in a population at high risk of stroke in Yubei District, Chongqing, China
Stroke is a condition marked by a high rate of morbidity, mortality, and impairment that is brought on by the rapid rupture of blood vessels in the brain or the obstruction of blood vessels that prevent blood from reaching the brain.1 The World Health Organization (WHO) lists the top 10 causes of mortality, with stroke coming in at number two. More than 6 million people worldwide lose their lives to stroke each year, with about 2 million of those deaths reported in China. Incidence of stroke is also higher in China than in Western populations.
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2023 Category: Neurology Authors: Yujia Zou, Xiaohui Zhang, Xiaoqing Bu, Ziyan Zhang, Yi Wu, Yanni Ren, Lihong Mu Source Type: research
Hospital Discharge and Readmissions Before and During the COVID-19 Pandemic for California Acute Stroke Inpatients
Stroke is a leading cause of death and disability in the United States, with approximately 795,000 new strokes occurring annually, including acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH).1 The Coronavirus Disease 2019 (COVID-19) pandemic has impacted all levels of care for stroke patients, such as delays in initial presentation, reduction in acute therapies, limitations of in-patient resources, delays or lack of initiation of secondary stroke prevention therapy, and limitations in rehabilitation services after hospital discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2023 Category: Neurology Authors: George P. Albert, Daryl C. McHugh, Debra E. Roberts, Adam G. Kelly, Remi Okwechime, Robert G. Holloway, Benjamin P. George Source Type: research
Application of intraoperative evoked potential monitoring in patients with anterior cerebral artery aneurysms
The location of the aneurysm can affect the relationship between changes in intraoperative neurophysiological monitoring indicators and postoperative outcomes. The current study aimed to evaluate the application value of motor evoked potential and somatosensory evoked potential monitoring in anterior cerebral artery aneurysm surgery.
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2023 Category: Neurology Authors: Jiajia Liu, Hao You, Dongze Guo, Zhibao Li, Yanwen Jin, Xing Fan, Hui Qiao Source Type: research
Short-term beneficial effects of human dental pulp stem cells and their secretome in a rat model of mild ischemic stroke
Although cell therapy has been applied in regenerative medicine for decades, recent years have seen greatly increased attention being given to the use of stem cell-based derivatives such as cell-free secretome. Dental pulp stem cells (DPSCs) are widely available, easily accessible, and have high neuroprotective and angiogenic properties. In addition, DPSC-derived secretome contains a rich mixture of trophic factors. The current investigation evaluated the short-term therapeutic effects of human DPSCs and their secretome in a rat model of mild ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2023 Category: Neurology Authors: Nahid Jashire Nezhad, Anahid Safari, Mohammad Reza Namavar, Mohammad Nami, Saeideh Karimi-Haghighi, Sareh Pandamooz, Mehdi Dianatpour, Negar Azarpira, Zahra Khodabandeh, Shahrokh Zare, Etrat Hooshmandi, Mahnaz Bayat, Maryam Owjfard, Seyedeh Shaghayegh Zaf Source Type: research
Validation of a neurovascular comorbidity index for risk adjustment of comorbid conditions among ischemic stroke patients receiving reperfusion treatment
To validate a comorbidity index specific to neurovascular patients and determine its performance relative to the Charlson Comorbidity Index (CCI) and Elixhauser Comorbidity Index (ECI) among ischemic stroke patients receiving reperfusion treatments.
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2023 Category: Neurology Authors: Ganesh Asaithambi, Summer L Martins Tags: Short Communication Source Type: research
Telemedicine Impact on Post-Stroke Outpatient Follow-up in an Academic Healthcare Network during the COVID-19 Pandemic
The objective of our study was to determine the impact of telemedicine on post-acute stroke clinic follow-up.
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2023 Category: Neurology Authors: Darwish Alabyad, Manet Lemuel-Clarke, Marlyn Antwan, Laura Henriquez, Samir Belagaje, Srikant Rangaraju, Ashlee Mosley, Jacqueline Cabral, Teri Walczak, Moges Ido, Patricia Hashima, Rana Bayakly, Kathyrn Collins, Loretta Sutherly-Bhadsavle, Cynthia Brashe Source Type: research
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL): A challenging diagnosis and a rare multiple sclerosis mimic
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is an extremely rare hereditary cerebral small vessel disease caused by homozygous or compound heterozygous mutations in the gene coding for high-temperature requirement A serine peptidase 1 (HtrA1). Given the rare nature of the disease, delays in diagnosis and misdiagnosis are not uncommon. In this article, we reported the first case of CARASIL from Saudi Arabia with a novel homozygous variant c.1156C>T in exon 7 of the HTRA1 gene.
Source: Journal of Stroke and Cerebrovascular Diseases - June 20, 2023 Category: Neurology Authors: Bader Shirah, Hussein Algahtani, Raghad Algahtani, Ahmed Alfares, Ahmed Hassan Tags: Case Report Source Type: research
Blood group and ischemic stroke, myocardial infarction, and peripheral vascular disease: A meta-analysis of over 145,000 cases and 2,000,000 controls
The ABO blood groups have been associated with the pathophysiology of cardiovascular diseases through an influence on two important blood clotting proteins, von Willebrand factor (vWF) and factor FVIII levels (FVIII).1,2 These proteins circulate in the plasma as a complex and are vital in normal haemostasis.1 The highest levels of FVIII and VWF are seen in non-O blood groups. Studies suggest a relationship between non-O blood groups and an increased risk of venous thromboembolism and other thrombotic episodes.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2023 Category: Neurology Authors: Zornitsa Lilova, Faiza Hassan, Malaika Riaz, Joshua Ironside, Gie Ken-Dror, Thang Han, Pankaj Sharma Source Type: research
