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Risk of suicide among stroke survivors in the United States
Stroke is the largest cause of disability and the 5th leading cause of death in the United States. Suicide is the 12th leading cause of death in the United States. However, little is known about the risk of suicide among people with a prior stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2023 Category: Neurology Authors: Ben Grobman, Neeharika Kothapalli, Arian Mansur, Christine Y Lu Source Type: research

A systematic review and evaluation of post-stroke depression clinical practice guidelines
Post-stroke depression is a depressive mood disorder that follows a cerebrovascular accident and is a burden on stroke patients. Its management is included in clinical practice guidelines focused on stroke, and the recommended treatment is selective serotonin reuptake inhibitors in conjunction with psychotherapy. Clinical practice guidelines are recommendations used to standardize best medical practice, but there is no current evaluation of guidelines containing post stroke depression recommendations.
Source: Journal of Stroke and Cerebrovascular Diseases - August 10, 2023 Category: Neurology Authors: James Graham Cross, Brandon R. May, Peter Q.M. Mai, Elizabeth Anderson, Connor Welsh, Shaeker Chandran, Kevin T. Chorath, Shelby Herr, Daniel Gonzalez Source Type: research

Associations of carotid artery flow parameters with MRI markers of cerebral small vessel disease and patterns of brain atrophy
Cerebral small vessel disease (CSVD) affects small arteries, arterioles, veins and capillaries of the brain. Although a common and often silent condition occurring among healthy elderly people, it is associated with stroke, dementia, gait disturbances, cognitive decline and depression.1 –4 Magnetic resonance imaging (MRI) markers of CSVD include: white matter changes (WMC), microbleeds (MB) and lacunar infarctions (LAC).5 They can be investigated either individually or be viewed as a dynamic whole-brain disease.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2023 Category: Neurology Authors: Katarina Ellstr öm, Kasim Abul-Kasim, Arkadiusz Siennicki-Lantz, Sölve Elmståhl Source Type: research

Association between physical activity levels and depressive symptoms in patients with minor ischemic stroke
Post-stroke depression (PSD) in stroke patients is a serious sequela. The incidence of depression in stroke patients is approximately 22% –35%.1,2 PSD is associated with serious outcomes, leading to increased risk of mortality and reduced quality of life.3 In addition, a previous study investigating the association between depression and stroke recurrence in ischemic stroke (IS) patients reported that post-IS depression is an indepe ndent risk factor for stroke recurrence.4 Thus, prevention of PSD is important, as this could lead to further adverse functional outcomes after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2022 Category: Neurology Authors: Ryota Ashizawa, Hiroya Honda, Kohei Yoshizawa, Yuto Kameyama, Yoshinobu Yoshimoto Source Type: research

Associations Between Fatigue and Disability, Depression, Health-Related Hardiness and Quality of Life in People with Stroke
Stroke is a common cause of mortality and morbidity which affects approximately 17 million people globally each year. Common symptoms associated with stroke are physical disabilities, impaired cognitive functions, depression, and fatigue, all of which can significantly impact health-related quality of life (HRQoL). To date, no research has explored the inter-relationship among fatigue, disability, depression, health-related hardiness, and quality of life in stroke survivors.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2022 Category: Neurology Authors: David Sibbritt, Jessica Bayes, Wenbo Peng, Jane Maguire, Jon Adams Source Type: research

Cerebrolysin ® and Environmental Enrichment, Alone or in Combination, Ameliorate Anxiety- and Depressive-Like Behaviors in a Post-Ischemic Depression Model in Mice
Global cerebral ischemia (GCI) as a multi-dimensional disorder resulting from wide ranges of pathologic events including; asphyxia, arrhythmia, cardiac arrest as well as shock and affecting the entire brain.1,2 GCI increases reactive oxygen species (ROS) and cytokines and reduces brain-derived neurotrophic factor (BDNF), resulting in neuronal dysfunction in wide array of brain sites.3,4 Given the vulnerability of regions such as the hippocampus to the ischemic insults,5,6 GCI is commonly complicated by psychiatric disorders, the most common of which are post-ischemic depression (PID) and anxiety.
Source: Journal of Stroke and Cerebrovascular Diseases - April 29, 2022 Category: Neurology Authors: Fereshteh Farajdokht, Farnaz Oghbaei, Saeed Sadigh-Eteghad, Alireza Majdi, Sepideh Rahigh Aghsan, Mehdi Farhoudi, Nazila Vahidi-Eyrisofla, Javad Mahmoudi Source Type: research

Psychological Burden in Stroke Survivors and Caregivers Dyads at the Rehabilitation Center of Kinshasa (Democratic Republic of Congo): A Cross-Sectional Study
This study aimed to assess the burden of depression and anxiety and covariates as well as its association with functional disability level among stroke survivors and caregivers dyads.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2022 Category: Neurology Authors: Germain Manzekele Bin Kitoko, Bives Mutume Nzanzu Vivalya, Martial Mumbere Vagheni, Thierry Matonda Ma Nzuzi, Sam Mampunza Lusambulu, Gilbert Mananga Lelo, Magloire Nkosi Mpembi, Samuel Mampunza Ma Miezi Source Type: research

Mood and Cognitive Trajectories Over the First Year after Mild Ischemic Stroke
Cognitive and mood dysfunction are major contributors to post-stroke disability. The longer-term trajectories of mood and cognition post-stroke remain unclear, as do which cognitive domains decline, improve, or remain stable after stroke, and in which patients. We aimed to characterize the cognitive trajectories of mild ischemic stroke survivors over one year compared to stroke-free controls, and to investigate whether symptoms of anxiety and depression were associated with cognitive function.
Source: Journal of Stroke and Cerebrovascular Diseases - February 5, 2022 Category: Neurology Authors: Deena Ebaid, Laura J. Bird, Laura J.E. McCambridge, Emilio Werden, Jennifer Bradshaw, Toby Cumming, Eugene Tang, Amy Brodtmann Source Type: research

Depression in Stroke Survivors: Ten-Year Follow-Up. Determinants of the Natural Course of Depressive Symptoms in Stroke Survivors in the Netherlands: The SMART-Medea Study
Stroke is one of the leading causes of mortality and a major cause of disability, due to impairments in functioning, limitations in activities, and restrictions in societal participation.20 Although these consequences vary widely between stroke survivors, the most common consequences are physical impairments, communication disorders, cognitive and emotional problems, and mood disturbances.13,50 Every year 15 million people suffer from stroke,30 in the Netherlands, 40.000 patients have a stroke each year28 Most stroke patients survive the initial illness and the greatest health effect is usually caused by the long-term consequences.
Source: Journal of Stroke and Cerebrovascular Diseases - January 21, 2022 Category: Neurology Authors: A. de Bekker, M.I. Geerlings, I.E. Uitewaal-Poslawsky, J.M. de Man-van Ginkel Source Type: research

Trends in Prevalence of Serious Psychological Distress and Depression Among Adults with Stroke in the United States
To examine national trends in prevalence of serious psychological distress and depression among adults with stroke in the United States (US) from 2004 to 2017, and variations across sociodemographic subgroups.
Source: Journal of Stroke and Cerebrovascular Diseases - December 27, 2021 Category: Neurology Authors: Liming Dong, Briana Mezuk, Lynda D. Lisabeth Source Type: research

Depression and Anxiety after Stroke in Young Adult Filipinos
Anxiety and depression are important psychiatric conditions to recognize after stroke.1 Poststroke depression (PSD) has been reported in around one third of stroke patients while poststroke anxiety affects a quarter of stroke patients.2 Depression and anxiety may also co-exist and persist in individuals long after a stroke.3 These complications adversely impact stroke outcome.4,5 Apart from restrictions in social function, they are associated with poorer quality of life, diminished functionality and increased risks of mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - December 4, 2021 Category: Neurology Authors: Katrina Hannah D. Ignacio, Jose Danilo B. Diestro, Jose Miguel M. Medrano, Sitti Khadija U. Salabi, Alvin J. Logronio, Sedric John V. Factor, Sharon D. Ignacio, Jose Leonard R. Pascual V, Maria Carissa C. Pineda-Franks Source Type: research

The Reliability and Validity of Post Stroke Depression Scale in Different Type of Post Stroke Depression Patients
Stroke is the second leading cause of death around the world, and approximately a third of all stroke survivors were have different degree of depression at any time after stroke.1 The repercussions of post-stroke depression (PSD) might cause extend psychological wellbeing, worsen rehabilitation outcomes, even lead to post-stroke mortality.2,3 Therefore, the early detection of PSD is essential to promote the prognosis and avoid unfortunate incidents.
Source: Journal of Stroke and Cerebrovascular Diseases - November 25, 2021 Category: Neurology Authors: Yingying Yue, Rui Liu, Jiu Chen, Yin Cao, Yanfeng Wu, Shining Zhang, Huajie Li, Jijun Zhu, Aiqin Wu, Yonggui Yuan Source Type: research

The Efficacy of Group Acceptance and Commitment Therapy for Preventing Post-Stroke Depression: A Randomized Controlled Trial
In this study, group Acceptance and Commitment Therapy (G-ACT) was performed in acute stroke patients to see if it can effectively relieve depressive symptoms and improve neurological function. The efficacy was also evaluated in stroke patients of different severity.
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2021 Category: Neurology Authors: Yunlian Niu, Shiying Sheng, Yan Chen, Jian Ding, Huajie Li, Shujing Shi, Jian Wu, Dan Ye Source Type: research

Efficacy of Fluoxetine for Post-Ischemic Stroke Depression in Tanzania
Post-stroke fluoxetine trials are primarily conducted in high-income countries. We characterize post-ischemic stroke depression in fluoxetine-treated and -untreated study participants in urban Tanzania.
Source: Journal of Stroke and Cerebrovascular Diseases - November 2, 2021 Category: Neurology Authors: Dylan R. Rice, Kigocha Okeng'o, Emmanuel Massawe, Seif Ismail, Notburga A. Mworia, Faraja Chiwanga, Boniface Kapina, Michael Wasserman, Farrah J. Mateen Source Type: research

Post-Stroke Depression in Patients with Large Spontaneous Intracerebral Hemorrhage
Post-stroke depression (PSD) is relatively under-studied in spontaneous intracerebral hemorrhage (ICH), the most disabling form of stroke.1 The highest incidence of PSD occurs within the first year after ICH, estimated at 15 –23%, and may decline over time.2–4
Source: Journal of Stroke and Cerebrovascular Diseases - September 10, 2021 Category: Neurology Authors: Radhika Avadhani, Richard E. Thompson, Lourdes Carhuapoma, Gayane Yenokyan, Nichol McBee, Karen Lane, Noeleen Ostapkovich, Agnieszka Stadnik, Issam A. Awad, Daniel F. Hanley, Wendy C. Ziai Source Type: research

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