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Source: Clinical Neurophysiology
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Total 151 results found since Jan 2013.

S186 Effect of reciprocal pedaling exercise on cortical reorganization and gait in stroke patients
Functional impairment of the lower limb is a major complication in stroke patients. The involvement of the cortex in pedaling has critical clinical implications to control of cyclical motor functions in patients with damaged cortical structures or cortical pathways.The study aimed at determining the effect of reciprocal pedaling exercise (RPE) on the gait and cortical reorganization in the stroke patients.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Mahmoud Rezk, Moshera Darweesh, Mohamed ElTamawy, Mye Basheer Source Type: research

S185 The effect of bilateral arm training on motor areas excitability in chronic stroke patients
Physical therapy exercises that do not enhance motor areas neuroplasticity lead to motor impairment especially at the upper extremity (UE) in the chronic stroke patients. The aim of this study was to assess the effect of using bilateral arm training on motor areas excitability (neuroplasticity) in the chronic stroke patients.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Walaa Ragab, Moshera Darwish, Mohamed El Tamawy, Ann Abdel Kader Source Type: research

O174 Preliminary results of testing the recoveriX system on stroke patients
Motor imagery based brain-computer interfaces (BCI) extract the movement intentions of subjects in real-time and can be used to control a cursor or medical devices. In the last years, the control of functional electrical stimulation (FES) devices drew researchers ’ attention for the post-stroke rehabilitation field. In here, a patient can use the movement imagery to artificially induce movements of the paretic arms through FES in real-time.Five patients who had a stroke that affected the motor system participated in the current study, and were trained acro ss 10 to 24 sessions lasting about 40min each with the recoveriX® system.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Danut Irimia, Rupert Ortner, Francisco Fernandes, Christoph Guger, Alexander Heilinger, Martin Walchshofer, Johannes Gruenwald Source Type: research

O-2-6-15. Immediate effects of anodal tDCS combined with patterned electrical stimulation on gait performance in patients with stroke
This study aimed to examine the immediate effects of anodal tDCS combined with PES on gait performance in patients with stroke. Twelve patients with subacute stroke participated in this double-masked, sham-controlled cross-over study. They randomly participated in the following sessions on separate days: (1) anodal tDCS+PES; (2) anodal tDCS+sham PES; (3) sham tDCS+PES.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Tomofumi Yamaguchi, Toshiyuki Fujiwara, Kazuhei Maeda, Tsuyoshi Tatemoto, Shigeo Tanabe, Yoko Takahashi, Katsuhiro Mizuno, Yoshihisa Masakado, Meigen Liu Source Type: research

P 167 The functional role of contralesional motor areas in the first days after stroke – an fMRI-guided online TMS-study
Neuroimaging studies in stroke patients with hemiparesis have shown altered brain activation in the contralesional hemisphere including the primary motor cortex (M1), dorsal premotor cortex (dPMC) and anterior intraparietal sulcus (aIPS) already in the first week after stroke (Rehme et al., 2011). The role of these regions for motor recovery is still under debate, with some studies suggesting a supportive influence (Lotze et al., 2006) while other point to a maladaptive role (Nowak et al., 2008).
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: L. Hensel, C. Tscherpel, J. Freytag, S. Ritter, M. Vollmer, L. Volz, G.R. Fink, C. Grefkes Tags: Poster Source Type: research

P 163 Combining TMS and EEG – a new tool to assess motor system integrity after stroke
Despite the wealth of neuroimaging studies regarding stroke pathophysiology and recovery after stroke, there is still a lack of clinically relevant biomarkers that allow to predict the potential of functional recovery and treatment response at individuals ’ level. Anovel approach is to test motor system integrity by means of combining transcranial magnetic stimulation (TMS) and electroencephalography (EEG). By recording TMS-evoked potentials (TEP), the cortical response to TMS, both local and network responses can be recorded and analyzed in indivi dual subjects (Rogasch and Fitzgerald, 2012; Ferreri, 2011).
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: C. Tscherpel, S. Dern, S. Bender, F. M üller-Dahlhaus, U. Ziemann, G.R. Fink, C. Grefkes Tags: Poster Source Type: research

P 66 Transcranial DC stimulation enhances recovery of swallowing function after stroke – a randomized clinical and MEG trial
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation tool that has shown some potential to aid motor rehabilitation following stroke. In the present clinical and neuroimaging study we evaluated whether tDCS is able to speed up the recovery of swallowing function in acute dysphagic stroke patients. Besides relating clinical effects with neuroplastic changes in cortical swallowing processing we aimed to identify factors influencing treatment success.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: S. Suntrup-Kr üger, C. Ringmaier, P. Muhle, R. Dziewas Tags: Poster Source Type: research

Revisiting interhemispheric imbalance in chronic stroke: a tDCS study
The immense burden of stroke-related disability has led to the development of noninvasive brain stimulation (NIBS) as a possible approach to augment neurorehabilitation of the paretic upper limb (Ackerley et al., 2010). Transcranial direct current stimulation (tDCS) is a polarity-dependent neuromodulatory technique that has demonstrated some benefit to motor function at the chronic stage (>6 months) post stroke, but effect sizes have varied (Jacobson et al., 2012; Kang et al., 2015).
Source: Clinical Neurophysiology - October 28, 2017 Category: Neuroscience Authors: Alana B McCambridge, James W Stinear, Winston D Byblow Source Type: research

35. Association of robot-assisted rehabilitation and non-invasive brain stimulation to improve upper limb function in chronic stroke patients
Previous studies suggested that both robotic rehabilitation and non-invasive brain stimulation could produce improvement in chronic stroke patients. It is still unknown whether their combination can produce synergistic effects. We designed a proof-of-principle, double-blinded, semi-randomized, sham-controlled trial to assess the safety and efficacy of this combination.Twenty severe upper limb-impaired chronic stroke patients were randomized to robot-assisted therapy associated with real or sham cTBS, delivered for 10 working days.
Source: Clinical Neurophysiology - November 11, 2017 Category: Neuroscience Authors: F. Capone, G. Di Pino, G. Pellegrino, L. Florio, L. Zollo, D. Simonetti, F. Ranieri, N. Brunelli, M. Corbetto, S. Miccinilli, M. Bravi, S. Milighetti, E. Guglielmelli, S. Sterzi, V. Di Lazzaro Source Type: research

26. A randomized controlled cross-over double blind study protocol on THC/CBD oromucosal spray as an add-on therapy for post-stroke spasticity
Understand if cannabinoids (THC:CBD) are useful in reducing post-stroke spasticity using a neurophysiological quantitative measure as primary endpoint.We will recruit 50 patients with spasticity following stroke to take THC:CBD in a double blind placebo-controlled crossover study. Spasticity will be assessed with a numeric rating scale for spasticity, the modified Ashworth scale and with the electromyographic recording of the stretch reflex. The cardiovascular risk will be assessed prior to inclusion.
Source: Clinical Neurophysiology - November 11, 2017 Category: Neuroscience Authors: L. Marinelli, M. Balestrino, L. Mori, L. Puce, G. Rosa, L. Giorello, A. Curr à, F. Fattapposta, C. Serrati, C. Gandolfo, G. Abbruzzese, C. Trompetto Source Type: research

P06-Cortical somatosensory processing after botulinum toxin therapy in post-stroke spasticity
In movement disorders, neurophysiology and functional MRI demonstrated abnormalities of sensorimotor processing, responding to peripheral botulinum toxin A (BoNT) treatment. We used Modified Ashworth scale (MAS) to assess spasticity and median nerve somatosensory evoked potentials (SEP) to study changes in sensorimotor cortical areas after BoNT therapy of post-stroke arm spasticity.Seventeen patients (10 men, 7 women, average age 60.2  years) with post-stroke arm spasticity were treated with BoNT into the affected muscles.
Source: Clinical Neurophysiology - March 13, 2018 Category: Neuroscience Authors: P. Hlu štík, T. Veverka, P. Hok, P. Otruba, A. Krobot, J. Zapletalová, P. Kaňovský Source Type: research

O-2-17. Influence of different types of orthoses on muscle synergy control during gait in stroke patients with hemiparesis
The purpose of this study was to verify the influence of lower limb orthoses on muscle synergy control during gait in stroke patients with hemiparesis. In four subjects with acute stroke, surface EMG signals from eight muscles of the paretic lower limb were measured during gait in two conditions (ankle foot orthosis; AFO or knee ankle foot orthosis; KAFO). The number of modules, muscle weightings and activation timing profile of each module were analyzed using non-negative matrix factorization. In two subjects (Fugl Meyer Assessment; FMA  > 20) who walked with mild assistance, three modules were identified during gait ...
Source: Clinical Neurophysiology - March 30, 2018 Category: Neuroscience Authors: Masanori Wakida, Kimihiko Mori, Yuta Chujo, Eiko Hirooka, Gwang-ho Kim, Koji Ohata, Kimitaka Hase Source Type: research

S21-1. A new analysis method using surface electromyography to assess finger function in patients with severe stroke
We have conducted our research into kinesthetic illusions induced by visual stimuli (KiNvis), which are sensations of being in motion that result from watching artificial images of the body part moving. Our previous studies revealed characteristic neural networks related to KiNvis; since then, we have initiated clinical studies adapting KiNvis in patients with stroke. In patients with severe stroke, it is often difficult to measure joint angles, because voluntary movement does not occur or simultaneous contraction of the agonist and antagonist muscles prevent controlled voluntary joint exercise.
Source: Clinical Neurophysiology - March 30, 2018 Category: Neuroscience Authors: Fuminari Kaneko Source Type: research

O-2-17. Influence of different types of orthoses on muscle synergy control during gait in stroke patients with hemiparesis
The purpose of this study was to verify the influence of lower limb orthoses on muscle synergy control during gait in stroke patients with hemiparesis. In four subjects with acute stroke, surface EMG signals from eight muscles of the paretic lower limb were measured during gait in two conditions (ankle foot orthosis; AFO or knee ankle foot orthosis; KAFO). The number of modules, muscle weightings and activation timing profile of each module were analyzed using non-negative matrix factorization. In two subjects (Fugl Meyer Assessment; FMA  > 20) who walked with mild assistance, three modules were identified during gait ...
Source: Clinical Neurophysiology - April 26, 2018 Category: Neuroscience Authors: Masanori Wakida, Kimihiko Mori, Yuta Chujo, Eiko Hirooka, Gwang-ho Kim, Koji Ohata, Kimitaka Hase Source Type: research

S21-1. A new analysis method using surface electromyography to assess finger function in patients with severe stroke
We have conducted our research into kinesthetic illusions induced by visual stimuli (KiNvis), which are sensations of being in motion that result from watching artificial images of the body part moving. Our previous studies revealed characteristic neural networks related to KiNvis; since then, we have initiated clinical studies adapting KiNvis in patients with stroke. In patients with severe stroke, it is often difficult to measure joint angles, because voluntary movement does not occur or simultaneous contraction of the agonist and antagonist muscles prevent controlled voluntary joint exercise.
Source: Clinical Neurophysiology - April 26, 2018 Category: Neuroscience Authors: Fuminari Kaneko Source Type: research