• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Safety, Tolerability, and Effectiveness of Dextromethorphan/Quinidine for Pseudobulbar Affect Among Study Participants With Traumatic Brain Injury: Results From the PRISM-II Open Label Study
Dextromethorphan 20mg /quinidine 10mg (DM/Q) was approved to treat pseudobulbar affect (PBA) based upon phase 3 trials conducted in participants with amyotrophic lateral sclerosis or multiple sclerosis. PRISM II evaluated DM/Q effectiveness, safety and tolerability for PBA following stroke, dementia or traumatic brain injury (TBI). Objective. To report results from the TBI cohort of PRISM II, including a TBI-specific functional scale. Design. Open-label trial evaluating twice daily DM/Q over 90 days.
Source: PM and R - February 22, 2018 Category: Rehabilitation Authors: Flora M. Hammond, William Sauve, Fred Ledon, Charles Davis, Andrea E. Formella Source Type: research

Effects of Functional Electrical Stimulation on Reducing Falls and Improving Gait Parameters in Multiple Sclerosis and Stroke
Loss of neuromuscular control of the ankle joint is a common impairment in neurologic conditions, leading to abnormal gait and a greater risk of falling. Limited information, however, is available on the effectiveness of functional electrical stimulation (FES) on reducing falls, and no studies have investigated its usefulness in improving lower limbs kinematics related to foot clearance and energy recovery.
Source: PM and R - November 3, 2016 Category: Rehabilitation Authors: Elisa Gervasoni, Riccardo Parelli, Marcin Uszynski, Alessandro Crippa, Alberto Marzegan, Angelo Montesano, Davide Cattaneo Tags: Original Research Source Type: research

Diagnosis and Treatment of Abductor Hallucis Focal Dystonia With Botulinum Toxin Injection: A Case Presentation
Orthopedic foot deformities can result from neurologic conditions such as stroke, multiple sclerosis, and cerebral palsy . In such cases, imaging studies of the foot are often not diagnostic of the underlying problem. Although it is not always considered, electrodiagnostic assessment can detect dystonia, spasticity, and neuropathy . The information gained from these electrodiagnostic studies can guide therapy, including medical and surgical management. This case study describes the successful evaluation and treatment of abducted hallux deformity by using electrodiagnostic testing and botulinum injection treatment.
Source: PM and R - August 1, 2013 Category: Rehabilitation Authors: Nathan S. Rosenberg, Ib R. Odderson Tags: Case Presentation Source Type: research