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Source: CNS Neuroscience and Therapeutics
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Total 476 results found since Jan 2013.
Outcomes in minor stroke patients treated with intravenous thrombolysis
CONCLUSIONS: Intravenous t-PA may be safe and effective in minor stroke (NIHSS ≤ 5) within a 4.5-h window and further randomized controlled trials are warranted.PMID:36942504 | DOI:10.1111/cns.14164
Source: CNS Neuroscience and Therapeutics - March 21, 2023 Category: Neuroscience Authors: Chunmiao Duan Yunyun Xiong Hong-Qiu Gu Shang Wang Kai-Xuan Yang Manjun Hao Xingquan Zhao Xia Meng Yongjun Wang Source Type: research
Functional recovery continues beyond 3 months post-basilar artery thrombectomy: A retrospective cohort study
CONCLUSION: Over a quarter of patients improved beyond 3 months. Future studies should adopt long-term follow up as primary outcome.PMID:36942501 | DOI:10.1111/cns.14182
Source: CNS Neuroscience and Therapeutics - March 21, 2023 Category: Neuroscience Authors: Lakshini Gunasekera Peter Mitchell Richard J Dowling Steven Bush Bernard Yan Source Type: research
Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition
CONCLUSION: Our results suggest that Tregs promote functional recovery after SCI by alleviating microglia inflammatory reaction via STAT3.PMID:36914969 | DOI:10.1111/cns.14161
Source: CNS Neuroscience and Therapeutics - March 14, 2023 Category: Neuroscience Authors: Rui Liu Ying Li Ziyue Wang Peng Chen Yi Xie Wensheng Qu Minghuan Wang Zhiyuan Yu Xiang Luo Source Type: research
Association between stress hyperglycemia and outcomes in patients with acute ischemic stroke due to large vessel occlusion
CONCLUSION: Stress hyperglycemia ratio, as measured by the glucose/HbA1C, was associated with a decreased odds of achieving a favorable functional outcome in patients with acute large vessel occlusion stroke at 90 days.PMID:36914967 | DOI:10.1111/cns.14163
Source: CNS Neuroscience and Therapeutics - March 14, 2023 Category: Neuroscience Authors: Zhouzhou Peng Jiaxing Song Linyu Li Changwei Guo Jie Yang Weilin Kong Jiacheng Huang Jinrong Hu Shuai Liu Yan Tian Dahong Yang Fengli Li Wenjie Zi Dongjing Xie Qingwu Yang Source Type: research
Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition
CONCLUSION: Our results suggest that Tregs promote functional recovery after SCI by alleviating microglia inflammatory reaction via STAT3.PMID:36914969 | DOI:10.1111/cns.14161
Source: CNS Neuroscience and Therapeutics - March 14, 2023 Category: Neuroscience Authors: Rui Liu Ying Li Ziyue Wang Peng Chen Yi Xie Wensheng Qu Minghuan Wang Zhiyuan Yu Xiang Luo Source Type: research
Association between stress hyperglycemia and outcomes in patients with acute ischemic stroke due to large vessel occlusion
CONCLUSION: Stress hyperglycemia ratio, as measured by the glucose/HbA1C, was associated with a decreased odds of achieving a favorable functional outcome in patients with acute large vessel occlusion stroke at 90 days.PMID:36914967 | DOI:10.1111/cns.14163
Source: CNS Neuroscience and Therapeutics - March 14, 2023 Category: Neuroscience Authors: Zhouzhou Peng Jiaxing Song Linyu Li Changwei Guo Jie Yang Weilin Kong Jiacheng Huang Jinrong Hu Shuai Liu Yan Tian Dahong Yang Fengli Li Wenjie Zi Dongjing Xie Qingwu Yang Source Type: research
Monocyte to high-density lipoprotein ratio predicts clinical outcomes after acute ischemic stroke or transient ischemic attack
CONCLUSIONS: Elevated MHR can independently predict all-cause death and poor functional outcome in patients with ischemic stroke or TIA.PMID:36914580 | DOI:10.1111/cns.14152
Source: CNS Neuroscience and Therapeutics - March 13, 2023 Category: Neuroscience Authors: Qin Xu Qiong Wu Lu Chen Hao Li Xue Tian Xue Xia Yijun Zhang Xiaoli Zhang Yongzhong Lin Yiping Wu Yongjun Wang Xia Meng Anxin Wang Source Type: research
Impact of the COVID-19 pandemic on acute stroke care: An analysis of the 24-month data from a comprehensive stroke center in Shanghai, China
CONCLUSIONS: During the 24 months of COVID-19, a prolongation of stroke onset to hospital arrival and to intravenous rt-PA administration times were noted. Meanwhile, acute stroke patients needed to stay in the ED for a longer time before hospitalization. Educational system support and process optimization should be pursued in order to acquire timely delivery of stroke care during the pandemic.PMID:36890633 | DOI:10.1111/cns.14148
Source: CNS Neuroscience and Therapeutics - March 8, 2023 Category: Neuroscience Authors: Qimin Hu Yiming Hu Yue Gu Xiaoyan Song Yijue Shen Haiyan Lu Li Zhang Peifeng Liu Guodong Wang Chunni Guo Kan Fang Qiaoshu Wang Source Type: research
Intravenous thrombolysis versus antiplatelet therapy in minor stroke patients with large vessel occlusion
CONCLUSION: In patients with minor stroke harboring LVO within 4.5-h time window, intravenous t-PA was associated with higher odds for the excellent functional outcome, as compared with the aspirin alone. Further randomized controlled trials are warranted.PMID:36880290 | DOI:10.1111/cns.14124
Source: CNS Neuroscience and Therapeutics - March 7, 2023 Category: Neuroscience Authors: Chunmiao Duan Yunyun Xiong Hongqiu Gu Shang Wang Kai-Xuan Yang Manjun Hao Xueyan Feng Xingquan Zhao Xia Meng Yongjun Wang Source Type: research
Srs11-92, a ferrostatin-1 analog, improves oxidative stress and neuroinflammation via Nrf2 signal following cerebral ischemia/reperfusion injury
CONCLUSION: The findings imply that Fer-1 analog AA9 may be suitable for further translational studies for the protection of neuronal damage via Nrf2 signal pathway-mediated oxidative stress and neuroinflammation in stroke and others neurological diseases.PMID:36852441 | DOI:10.1111/cns.14130
Source: CNS Neuroscience and Therapeutics - February 28, 2023 Category: Neuroscience Authors: Yuhua Chen Wei He Hong Wei Cuicui Chang Lingjian Yang Jiao Meng Tianlin Long Quanhua Xu Chi Zhang Source Type: research
