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Source: Stroke
Drug: Aspirin
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Total 58 results found since Jan 2013.
Efficacy and Safety of Ticagrelor in Relation to Aspirin Use Within the Week Before Randomization in the SOCRATES Trial Clinical Sciences
Conclusions—In this secondary analysis from SOCRATES, fewer primary end points occurred on ticagrelor treatment than on aspirin in patients receiving aspirin before randomization, but there was no significant treatment-by-prior-aspirin interaction. A new study will investigate the benefit-risk of combining ticagrelor and aspirin in patients with acute cerebral ischemia (URL: https://www.clinicaltrials.gov. Unique identifier: NCT03354429).Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT01994720.
Source: Stroke - June 25, 2018 Category: Neurology Authors: K.S. Lawrence Wong, Pierre Amarenco, Gregory W. Albers, Hans Denison, J. Donald Easton, Scott R. Evans, Peter Held, Anders Himmelmann, Scott E. Kasner, Mikael Knutsson, Per Ladenvall, Kazuo Minematsu, Carlos A. Molina, Yongjun Wang, S. Claiborne Johnston Tags: Ischemic Stroke Original Contributions Source Type: research
Cerebrovascular Accidents During Mechanical Circulatory Support Clinical Sciences
Conclusions—Stroke is a major cause of morbidity and mortality in patients on LVAD support. Chronic obstructive pulmonary disease increases the risk of ischemic stroke, whereas dialysis may increase the risk of hemorrhagic stroke. Although any stroke increases mortality, post-LVAD hemorrhagic stroke was associated with higher mortality compared with ischemic stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Saef Izzy, Daniel B. Rubin, Firas S. Ahmed, Feras Akbik, Simone Renault, Katelyn W. Sylvester, Henrikas Vaitkevicius, Jennifer A. Smallwood, Michael M. Givertz, Steven K. Feske Tags: Heart Failure, Complications, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Statins and the Risk of Intracerebral Hemorrhage in Patients With Previous Ischemic Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions—Statin use was not associated with an increased risk of ICH among patients with a previous history of IS/TIA.
Source: Stroke - November 27, 2017 Category: Neurology Authors: David Gaist, Larry B. Goldstein, Lucia Cea Soriano, Luis Alberto Garcia Rodriguez Tags: Secondary Prevention, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
One-Year Outcomes After Minor Stroke or High-Risk Transient Ischemic Attack Clinical Sciences
Conclusions—Contemporary secondary stroke prevention strategies based on thorough diagnostic evaluation may contribute to the low subsequent vascular event rates observed in real-world clinical practice in Korea.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Hong-Kyun Park, Beom Joon Kim, Moon-Ku Han, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Tai Hwan Park, Sang-Soon Park, Kyung Bok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Byung-Chul Lee, Kyung-Ho Yu, M Tags: Quality and Outcomes, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Letter by Spence Regarding Article, “Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis” Letter to the Editor
Source: Stroke - September 25, 2017 Category: Neurology Authors: J. David Spence Tags: Platelets, Secondary Prevention Letters to the Editor Source Type: research
Response by Lee and Ovbiagele to Letter Regarding Article, “Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis” Letter to the Editor
Source: Stroke - September 25, 2017 Category: Neurology Authors: Meng Lee, Bruce Ovbiagele Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Letters to the Editor Source Type: research
Ticagrelor Versus Aspirin in Acute Embolic Stroke of Undetermined Source Clinical Sciences
Background and Purpose—Ticagrelor is an effective antiplatelet therapy among patients with atherosclerotic disease and, therefore, could be more effective than aspirin in preventing recurrent stroke and cardiovascular events among patients with embolic stroke of unknown source (ESUS), which includes patients with ipsilateral stenosis
Source: Stroke - August 28, 2017 Category: Neurology Authors: Pierre Amarenco, Gregory W. Albers, Hans Denison, J. Donald Easton, Scott R. Evans, Peter Held, Michael D. Hill, Jenny Jonasson, Scott E. Kasner, Per Ladenvall, Kazuo Minematsu, Carlos A. Molina, Yongjun Wang, K.S. Lawrence Wong, S. Claiborne Johnston Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin Brief Report
Conclusions—Among patients who experience an ischemic stroke or transient ischemic attack while on aspirin monotherapy, the addition of or a switch to another antiplatelet agent, especially in the first days after index event, is associated with fewer future vascular events, including stroke.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Meng Lee, Jeffrey L. Saver, Keun-Sik Hong, Neal M. Rao, Yi-Ling Wu, Bruce Ovbiagele Tags: Secondary Prevention, Meta Analysis, Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research
Letter by Hasan et al Regarding Article, “Aspirin and Risk of Subarachnoid Hemorrhage: Systematic Review and Meta-Analysis” Letter to the Editor
Source: Stroke - June 26, 2017 Category: Neurology Authors: David M. Hasan, Emine Bayman, Joseph Broderick Tags: Aneurysm Letters to the Editor Source Type: research
Aspirin’s Benefits Were Previously Underestimated and Are Primarily Accrued in the Acute Setting Emerging Therapy Critique
Source: Stroke - April 24, 2017 Category: Neurology Authors: Pierre Amarenco, Anthony S. Kim Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Emerging Therapy Critiques Source Type: research
Aspirin and Risk of Subarachnoid Hemorrhage Clinical Sciences
Conclusions—Current evidence suggests that short-term (
Source: Stroke - April 24, 2017 Category: Neurology Authors: Kevin Phan, Justin M. Moore, Christoph J. Griessenauer, Christopher S. Ogilvy, Ajith J. Thomas Tags: Risk Factors, Treatment, Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Letter by Moris et al Regarding Article, “Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes)” Letter to the Editor
Source: Stroke - March 27, 2017 Category: Neurology Authors: Demetrios Moris, Chris Bakoyiannis, Efthymios Avgerinos Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Letters to the Editor Source Type: research
Response by Wang and Johnston to Letter Regarding Article, “Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes)” Letter to the Editor
Source: Stroke - March 27, 2017 Category: Neurology Authors: Yongjun Wang, S. Claiborne Johnston Tags: Ischemic Stroke Letters to the Editor Source Type: research
Impact of Glycemic Control on Efficacy of Clopidogrel in Transient Ischemic Attack or Minor Stroke Patients With CYP2C19 Genetic Variants Clinical Sciences
Background and Purpose—Dysglycemia may influence the predictive value of CYP2C19 loss-of-function allele for clinical efficacy of antiplatelet drug, but the role of glycated albumin (GA) remains unclear in patients with stroke on antiplatelet drugs.Methods—The CHANCE trial (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events) included 2933 patients who had GA levels and CYP2C19 genotyping. Cox proportional hazards model was used to assess the interaction between CYP2C19 loss-of-function allele (*2, *3) carrier status and the effect of antiplatelet therapy based on their GA levels.Results—...
Source: Stroke - March 27, 2017 Category: Neurology Authors: Yi Lin, Anxin Wang, Jiejie Li, Jinxi Lin, David Wang, Xia Meng, Lixian Ou, Weiqi Chen, Xingquan Zhao, Liping Liu, Yilong Wang, Yongjun Wang Tags: Biomarkers, Secondary Prevention, Genetics, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Risk Factors of Subacute Thrombosis After Intracranial Stenting for Symptomatic Intracranial Arterial Stenosis Brief Report
Conclusions—Tandem stenting and antiplatelet resistance might contribute to the development of SAT after intracranial stenting in patients with symptomatic intracranial arterial stenosis.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Xuan Sun, Xu Tong, Wai Ting Lo, Dapeng Mo, Feng Gao, Ning Ma, Bo Wang, Zhongrong Miao Tags: Stent, Ischemic Stroke, Stenosis, Thrombosis Brief Reports Source Type: research
