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Source: Neurocritical Care
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Total 235 results found since Jan 2013.
Serum Glial Fibrillary Acidic Protein in Acute Stroke
Source: Neurocritical Care - March 4, 2020 Category: Neurology Source Type: research
Neurological Pupil Index as an Indicator of Neurological Worsening in Large Hemispheric Strokes
ConclusionsQuantitative monitoring of the pupillary response using an automated pupillometer could be a useful and noninvasive tool for detecting neurological deterioration due to cerebral edema in large hemispheric stroke patients.
Source: Neurocritical Care - February 23, 2020 Category: Neurology Source Type: research
Diagnostic Accuracy of Glial Fibrillary Acidic Protein and Ubiquitin Carboxy - Terminal Hydrolase - L1 Serum Concentrations for Differentiating Acute Intracerebral Hemorrhage from Ischemic Stroke
ConclusionsGFAP may differentiate ICH from ischemic stroke and stroke mimics. A point-of-care test to distinguish between ischemic and hemorrhagic strokes might facilitate triage to different treatment pathways or locations, or be used to select patients for trials of ultra-early interventions.
Source: Neurocritical Care - February 23, 2020 Category: Neurology Source Type: research
Relationship of White Matter Lesions with Intracerebral Hemorrhage Expansion and Functional Outcome: MISTIE II and CLEAR III
ConclusionsConcomitant WML does not increase the odds for HE in patients with ICH but increases the odds for poor functional outcome.Clinical Trial Registrationhttp://www.clinicaltrials.gov trial-identifiers: NCT00224770 and NCT00784134.
Source: Neurocritical Care - February 4, 2020 Category: Neurology Source Type: research
Outcomes of Acute Stroke Patients Requiring Mechanical Ventilation: Study Protocol for the SPICE Multicenter Prospective Observational Study
ConclusionsThe SPICE multicenter study will investigate 1-year outcomes, ethical issues, as well as care pathways of acute stroke patients requiring invasive ventilation in the ICU. Gathered data will delineate human resources and facilities needs for adequate management. The identification of prognostic factors at the acute phase will help to identify patients who may benefit from prolonged intensive care and rehabilitation.Trial registration: NCT03335995.
Source: Neurocritical Care - February 4, 2020 Category: Neurology Source Type: research
Predicting Malignant Cerebral Edema After Large Hemispheric Stroke
Source: Neurocritical Care - January 31, 2020 Category: Neurology Source Type: research
Beta-Blockade in Aneurysmal Subarachnoid Hemorrhage: a Systematic Review and Meta-Analysis
ConclusionsIn adult patients with aSAH, beta-blocker therapy is associated with a mortality benefit. Studies are generally of a low quality with considerable clinical heterogeneity. Prospective large interventional trials with patient centered outcomes are required to validate this finding.
Source: Neurocritical Care - January 27, 2020 Category: Neurology Source Type: research
Prevalence, Clinical Characteristics, and Outcomes Related to Ventilator-Associated Events in Neurocritically Ill Patients
ConclusionsVAE are prevalent in the neurocritically ill. They result in an increased duration of mechanical ventilation and ICU length of stay, but may not be associated with in-hospital mortality or discharge to home.
Source: Neurocritical Care - January 22, 2020 Category: Neurology Source Type: research
Resource Allocation: Stable Patients Remain Stable 12 –24 h Post-tPA
ConclusionsNew onset of neurologic deterioration is rare 12 –24 h after treatment of acute stroke. Stable patients with low NIHSS scores and no ICU needs may not require intensive monitoring greater than 12 h post-treatment.
Source: Neurocritical Care - December 8, 2019 Category: Neurology Source Type: research
Emergency Free-Hand Bedside Catheter Evacuation of Large Intracerebral Hematomas Following Thrombolysis for Ischemic Stroke: A Case Series
ConclusionsEmergency free-hand bedside catheter aspiration is a reasonable option for hematoma evacuation in large thrombolysis-associated sICH when performed by experienced neurosurgeons. Larger studies would help in determining the generalizability of our findings to other centers and assessing their impact on functional outcome.
Source: Neurocritical Care - December 2, 2019 Category: Neurology Source Type: research
Serum Caspase-3 Levels and Early Mortality of Patients with Malignant Middle Cerebral Artery Infarction
ConclusionsThe novel and more important findings of our study were that high serum caspase-3 levels were associated with mortality in MMCAI patients.
Source: Neurocritical Care - November 21, 2019 Category: Neurology Source Type: research
Risk Factors for Dysphagia and the Impact on Outcome After Spontaneous Subarachnoid Hemorrhage
ConclusionsDysphagia is a frequent complication of non-traumatic SAH and associated with poor functional outcome, infectious complications, and prolonged stay in the intensive care unit. Early identification of high-risk patients is needed to timely stratify individual patients for dysphagia treatment.
Source: Neurocritical Care - November 14, 2019 Category: Neurology Source Type: research
Sonographic Demonstration of a Perfusion-Dependent Stroke with Negative MRI and a Flow-Limiting Stenosis
Source: Neurocritical Care - October 28, 2019 Category: Neurology Source Type: research
Vitamin K Antagonist (Phenprocoumon) and Subarachnoid Hemorrhage: A Single-Center, Matched-Pair Analysis
ConclusionPatients with phenprocoumon treatment at the time of SAH are significantly older, admission status is worse, and 30-day mortality rates are significantly higher compared to patients without anticoagulant treatment. However, outcome at 6 months did not differ to the matched-pair control group but seems to be strongly associated with the underlying cardiovascular disease. Treatment of these patients is challenging and should be performed on an interdisciplinary base in each individual case. Careful decision-making regarding discont inuation and bridging of anticoagulation and close observation is mandatory.
Source: Neurocritical Care - October 27, 2019 Category: Neurology Source Type: research
Neurocritical Care Quality Improvement Practices: A Survey of Members of the Neurocritical Care Society
ConclusionA dedicated staffed NCCU QI program occurs in a minority of NCC units, and the lack of such programs may lead to clinician dissatisfaction. Institutional and departmental support may be critical elements of a successful and satisfactory implementation of NCCU QI.
Source: Neurocritical Care - October 14, 2019 Category: Neurology Source Type: research
