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Source: Heart Rhythm
Condition: Ischemic Stroke

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Total 61 results found since Jan 2013.

The Decrease in Peak Atrial Longitudinal Strain in Patients with Atrial Fibrillation as a Practical Parameter for Stroke Risk Stratification
Decreased peak atrial longitudinal strain (LA strain) derived from two-dimensional speckle tracking is frequently observed in patients with atrial fibrillation (AF) and associated with the risk of ischemic stroke.
Source: Heart Rhythm - December 28, 2020 Category: Cardiology Authors: Jo-Nan Liao, Tze-Fan Chao, Chung-Lieh Hung, Shih-Ann Chen Source Type: research

Relationship between Device-detected Burden and Duration of Atrial Fibrillation and Risk of Ischemic Stroke
Wider availability of continuous rhythm monitoring has made it feasible to incorporate metrics of atrial fibrillation burden and duration into the decision to initiate anticoagulation. However, the relationship between thresholds of burden and duration and underlying risk factors at which anticoagulation should be considered remains unclear.
Source: Heart Rhythm - October 23, 2020 Category: Cardiology Authors: Mounir Al-Gibbawi, Hakeem O. Ayinde, Neal K. Bhatia, Mikhael F. El-Chami, Stacy B. Westerman, Angel R. Leon, Anand D. Shah, Anshul M. Patel, David B. De Lurgio, Christine M. Tompkins, Michael S. Lloyd, Faisal M. Merchant, Soroosh Kiani Source Type: research

EP News: Clinical
Osmancik and colleagues (J Am Coll Cardiol 2020;75:3122 –3135, PMID 32586585) compared left atrial appendage closure (LAAC) with direct oral anticoagulants (DOAC) in a multicenter, randomized, noninferiority trial. A high-risk patient cohort (CHA2DS2-VASc: 4.7 ± 1.5) was randomized to receive LAAC (n = 201) or DOAC (n = 201). At 19.9 months of follow- up, the annual rates of the primary outcome were 10.99% with LAAC and 13.42% with DOAC (d ratio [HR]: 0.84; P = .44; P = .004 for noninferiority). There were no differences between groups for the components of the composite endpoint: all-stroke/transient ischemic attack (H...
Source: Heart Rhythm - July 3, 2020 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research

Impact of atrial fibrillation/flutter on the in-hospital mortality of ischemic stroke patients
Stroke is the second leading cause of death worldwide. Ischemic strokes, which are caused by atrial fibrillation/flutter (AF) may be more devastating than those without AF.
Source: Heart Rhythm - October 3, 2019 Category: Cardiology Authors: Karsten Keller, Lukas Hobohm, Philip Wenzel, Thomas M ünzel, Christine Espinola-Klein, Mir A. Ostad Source Type: research

EP News: Allied Professionals
Di Biase et  al (J Am Coll Cardiol 2019;74:1019, PMID 31439209) sought to assess the incidence of thromboembolic (TE) events such as stroke and transient ischemic attack (TIA) in patients with atrial fibrillation (AF) undergoing ablation for AF that included left atrial appendage (LAA) isolation (LAAI). The st udy group comprised all patients who underwent LAAI as part of their ablation strategy and who were without AF 6 months after ablation. All patients were continued on oral anticoagulation (OAC) with either warfarin or direct oral anticoagulant (DOAC) for the first 6 months.
Source: Heart Rhythm - September 15, 2019 Category: Cardiology Authors: Erica S. Zado Tags: EP News Source Type: research

Stroke and Dementia Risk in Patients with and without Atrial Fibrillation and Carotid Arterial Disease
We sought to understand the risks of stroke, transient ischemic attack(TIA), and dementia in patients with and without atrial fibrillation (AF) and carotid arterial disease (CD), or a combination of both, and determine if therapies for each disease may influence risks. 11,572 patients were included and matched into 4 groups of 2,893 by the presence of AF and CD. CD and AF augment risk of stroke/TIA and dementia in the general population and the coexistence of both diseases is additive in risk. Ablation of AF was associated with lower risk, the magnitude of which was greater in those with CD.
Source: Heart Rhythm - July 8, 2019 Category: Cardiology Authors: T. Jared Bunch, Tami L. Bair, Brian G. Crandall, Michael J. Cutler, John D. Day, Kevin G. Graves, Victoria Jacobs, Charles Mallender, Jeffrey S. Osborn, J. Peter Weiss, Heidi T. May Source Type: research

A New Model to Predict Ischemic Stroke in Patients with Atrial Fibrillation Using Warfarin or Direct Oral Anticoagulants
Stroke risk stratification scores (e.g., CHA2DS2-VASc) are used to tailor therapeutic recommendations for patients with atrial fibrillation (AF) in different risk groups.
Source: Heart Rhythm - December 11, 2018 Category: Cardiology Authors: J ’Neka S. Claxton, Richard F. MacLehose, Pamela L. Lutsey, Faye L. Norby, Lin Y. Chen, Wesley T. O’Neal, Alanna M. Chamberlain, Lindsay G.S Bengtson, Alvaro Alonso Source Type: research

Atrial fibrillation occurring during head-up tilt testing: Once detected, atrial fibrillation should be monitored, regardless of how it is detected
Atrial fibrillation (AF) often progresses to more sustained forms and increases the risk of ischemic stroke or sinus node dysfunction. However, there have been no data on the clinical outcomes of patients who developed AF during head-up tilt testing (HUT).
Source: Heart Rhythm - December 4, 2018 Category: Cardiology Authors: Jun Hyung Kim, Sung Ho Lee, Seung-Jung Park, Kyoung Min Park, Young Keun On, June Soo Kim Source Type: research

Atrial Fibrillation Occurring During Head-up Tilt Test: Once detected, AF should be monitored, regardless of how it is detected
Atrial fibrillation (AF) often progresses to more sustained forms and raises the risk of ischemic stroke or sinus node dysfunction (SND). However, there has been no data on the clinical outcomes of AF developed during head-up tilt testing (HUT).
Source: Heart Rhythm - December 4, 2018 Category: Cardiology Authors: Jun Hyung Kim, Sung Ho Lee, Seung-Jung Park, Kyoung Min Park, Young Keun On, June Soo Kim Source Type: research

Electrical isolation of the left atrial appendage increases the risk of ischemic stroke and transient ischemic attack regardless of postisolation flow velocity
Electrical isolation of the left atrial appendage (LAA) is associated with a lower rate of atrial fibrillation (AF) recurrence in patients undergoing radiofrequency catheter ablation. However, LAA isolation can significantly impair LAA contractility.
Source: Heart Rhythm - November 28, 2018 Category: Cardiology Authors: Yun Gi Kim, Jaemin Shim, Suk-Kyu Oh, Kwang-No Lee, Jong-Il Choi, Young-Hoon Kim Tags: Featured Article Source Type: research

EP News: Clinical
Sindet-Pedersen et  al (J Am Coll Cardiol 2018;72:1790, PMID 30286922) investigated the risk of bleeding, ischemic stroke, myocardial infarction (MI), and all-cause mortality associated with direct oral anticoagulants (DOACs) compared with vitamin K antagonists (VKAs) in combination with aspirin, clopidogrel, or both in patients with atrial fibrillation (AF) after MI and/or percutaneous coronary intervention (PCI). Overall, 3222 patients were included in the retrospective registry analysis; 875 (27%) were treated with VKA+single antiplatelet therapy (SAPT), 595 (18%) were treated with DOAC+SAPT, 1074 (33%) were treated wi...
Source: Heart Rhythm - November 23, 2018 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research

Seeing is Believing: The Importance of Continuous Monitoring to Unmask the Real-World Atrial Fibrillation Recurrence after Ablation
Atrial fibrillation (AF) is a common arrhythmia encountered in clinical practice that contribute to hemodynamic abnormalities, thromboembolic events and hospitalizations.1 The prevalence of AF is around 1% in the general population, substantially increases with age and is estimated to reach 4% in 2050.2, 3 Compared with patients without AF, patients with AF has an increased risk of dementia (hazard ratio [HR]=1.56), myocardial infarction (HR=1.62), sudden cardiac death (HR=1.83), mortality (HR=2.61), heart failure (HR=3.31) and ischemic stroke (HR=3.34).
Source: Heart Rhythm - July 28, 2018 Category: Cardiology Authors: Ting-Yung Chang, Chin-Yu Lin, Shih-Ann Chen Source Type: research

Seasonal variation in the risk of ischemic stroke in patients with atrial fibrillation: A nationwide cohort study
Several cardiovascular diseases exhibit seasonal variations, but data about cold temperature and risk of ischemic stroke in patients with atrial fibrillation (AF) are limited.
Source: Heart Rhythm - July 2, 2018 Category: Cardiology Authors: Jo-Nan Liao, Tze-Fan Chao, Chia-Jen Liu, Su-Jung Chen, Chung-Lieh Hung, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Fa-Po Chung, Tzeng-Ji Chen, Gregory Y.H. Lip, Shih-Ann Chen Source Type: research

Irregularity and lack of p-waves in short tachycardia episodes predict atrial fibrillation and ischemic stroke
Atrial fibrillation (AF) is defined as an irregular supraventricular tachycardia (SVT) without p-waves, with a duration>30s. It is not known whether AF characteristics in shorter SVT episodes predict AF and stroke.
Source: Heart Rhythm - February 12, 2018 Category: Cardiology Authors: Linda S.B. Johnson, Anders P. Persson, Per Wollmer, Steen Juul-M öller, Tord Juhlin, Gunnar Engström Source Type: research

Irregularity and lack of p waves in short tachycardia episodes predict atrial fibrillation and ischemic stroke
Atrial fibrillation (AF) is defined as an irregular supraventricular tachycardia (SVT) without p waves, with duration>30 seconds. Whether AF characteristics during short SVT episodes predict AF and stroke is not known.
Source: Heart Rhythm - February 12, 2018 Category: Cardiology Authors: Linda S.B. Johnson, Anders P. Persson, Per Wollmer, Steen Juul-M öller, Tord Juhlin, Gunnar Engström Source Type: research