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Source: Heart Rhythm
Condition: Ischemic Stroke

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Total 61 results found since Jan 2013.

EP News: Clinical
Lakkireddy et  al (Circulation 2021;144:1543, PMID 34459659) evaluated the safety and effectiveness of the Amulet left atrial appendage occluder (A) compared with the Watchman device (W). Patients with nonvalvular atrial fibrillation at an increased risk of stroke were randomly assigned (1:1) to A or W. The prim ary end points included safety (composite of procedure-related complications, death, or major bleeding at 12 months) and effectiveness (composite of ischemic stroke or systemic embolism at 18 months).
Source: Heart Rhythm - December 7, 2021 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research

B-po02-045 utility of a smartphone connected electrocardiogram recorder for detecting atrial fibrillation in post-stroke patients
Atrial fibrillation is one of the important causes of ischemic stroke. Routine 24-hour monitoring reveals latent atrial fibrillation in up to about 5% of cases. Despite the fact that today there are many ways to record heart rate, there is no precise algorithm that allows to detect atrial fibrillation in patients who have survived ischemic stroke of unknown etiology.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Ayan Abdrakhmanov, Idalya Rakhimova, Zhanasyl Suleymen, Zhanar Abdrakhmanova Source Type: research

B-po03-156 procedural complications and in-hospital outcomes from left atrial appendage occlusion device implantation in patients with chronic and end stage renal disease
The Watchman device has emerged as an alternative strategy to oral anticoagulation for mitigating ischemic stroke risk in selected patients with atrial fibrillation (AF), but safety data in patients with kidney disease are limited.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Muhammad Bilal Munir, Muhammad Zia Khan, Douglas Darden, Deepak Kumar Pasupula, Sudarshan Balla, Frederick T. Han, Ryan Reeves, Jonathan C. Hsu Source Type: research

B-po03-152 left atrial appendage occlusion in patients with intracranial hemorrhage
Patients with prior intracranial hemorrhage (ICH) and atrial fibrillation (AF) are at increased risk of recurrent bleeding; and often not treated with oral anticoagulation despite high risk of ischemic stroke.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Jalaj Garg, Siddharth Shah, Kuldeep Bharat Shah, Mohit K. Turagam, Andrea Natale, Dhanunjaya R. Lakkireddy Source Type: research

B-po03-148 risk stratification for ischemic stroke and major bleeding in patients without atrial fibrillation - validity of cha2ds2-vasc and has-bled score
Atrial fibrillation (AF) is the most common arrhythmia. Recent cardiac implantable electronic devices (CIEDs) have led to an improvement in the early detection of AF episodes. ESC guidelines for the management of AF recommend the use of CHA2DS2-VASc score as class I to predict the risk of ischemic stroke in patients with AF. However, the validity of the CHA2DS2-VASc and HAS-BLED scores to predict ischemic stroke and major bleeding events in patients without AF remains unclear.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Miyo Nakano, Yusuke Kondo, Masahiro Nakano, Takatsugu Kajiyama, Ryo Ito, Haruhiro Takahira, Mari Kitagawa, Masafumi Sugawara, Toshinori Chiba, Yoshio Kobayashi Source Type: research

B-po04-162 risk of recurrent stroke with runs of supraventricular tachycardia and premature atrial contraction burden
Ischemic strokes are a significant cause of mortality in the United States, leading to roughly 140,000 deaths per year. Approximately one third are classified as cryptogenic. Previous studies have shown premature atrial contractions (PAC) and short runs of supraventricular tachycardia (SVT) increase the risk of stroke.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Weston Harkness, Jeff M. Hsing, Julie Davidson Source Type: research

B-po04-115 hypertension and abnormal renal function increased the risk of ischemic stroke in anticoagulated ehra type-1 valvular atrial fibrillation
Atrial fibrillation (AF) increases the risk of stroke substantially, therefore many scores have been developed to risk stratify these patients. However, most of the previous studies have focused on non-valvular AF. The most widely used risk stratification score is the CHA2DS2-VASC score. Unfortunately, the validation of this score in valvular AF is poor.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Rena Winanti, Sunu Budhi Raharjo, Rina Ariani, Dicky A. Hanafy, Celly Anantaria Atmadikoesoemah, Prima Almazini, Yoga Yuniadi Source Type: research

B-po05-144 comparing sodium glucose cotransporter 2 inhibitors and dipeptidyl peptidase-4 inhibitors on new-onset atrial fibrillation and ischemic stroke
Given the susceptibility of patients with type 2 diabetes mellitus towards cerebrovascular complications, there is increasing research on the cerebrovascular-protective effects of novel anti-diabetic agents. However, few studies have compared sodium glucose cotransporter-2 inhibitor (SGLT2I) and dipeptidyl peptidase-4 inhibitor (DPP4I) in their effects on stroke and atrial fibrillation (AF).
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Sharen Lee, Jiandong Zhou, Xiansong Wang, Carlin Chang, Tong Liu, Dong Chang, Wing Tak Wong, William K.K. Wu, Bernard M.Y. Cheung, Gary Tse, Qingpeng Zhang Source Type: research

B-po05-142 atrial fibrillation patient with low cha2ds2vasc score may still benefit from oral anticoagulation therapy for ischemic stroke prevention: the need to refine stroke risk assessment scores
The CHA2DS2VASC score has shown limitations in the assessment of ischemic stroke (IS) risk in atrial fibrillation (AF) patients.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Lilas Dagher, Abdel Hadi El Hajjar, Hunter Edward Launer, Christopher Pottle, Aneesh Dhore Tarek Ayoub, Nassir F. Marrouche Source Type: research

B-po05-086 structural and tissue remodeling of the left atrium and left atrial appendage after atrial fibrillation ablation
Large left atrium appendage (LAA) orifice area and an increased left atrium (LA) volume have been associated with an increased risk of ischemic stroke. Catheter ablation (CA) of atrial fibrillation (AF) leads to anatomical and tissue changes within the LA and LAA.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Yichi Zhang, Lilas Dagher, Abdel Hadi El Hajjar, Aneesh Dhore, Alan Morris, Eugene Kholmovski, Chao Huang, Raman Danrad, Tarek Ayoub, Nassir Marrouche Source Type: research

B-po05-059 left atrial appendage occlusion (laao) using watchman device in end stage renal disease: analysis from national inpatient sample
Percutaneous occlusion of left atrial appendage (LAAC) using WATCHMAN device is a widely accepted alternative to oral anticoagulants to prevent ischemic stroke in atrial fibrillation. There is limited data regarding the utilization and safety of this intervention in patients with ESRD.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Shakeel Jamal, Ehizogie Edigin, Asim Kichloo, Zulfiqar Qutrio Baloch, Sardar Hassan Ijaz, Abdul Mannan Khan Minhas, Sandeep Banga, Abbas Ali, George Abela Source Type: research

EP News: Allied Professionals
In this multicenter, randomized trial (Whitlock et al. New Engl J Med. 2021;384:2081-91. PMID: 33999547), the investigators sought do determine whether surgical left atrial appendage occlusion (LAAO) prevents ischemic stroke in patients with atrial fibrillation (AF). Patients with AF and CHA2DS2-VASc score of at least 2 who were scheduled to undergo cardiac surgery were randomized on a 1:1 basis to surgical LAAO or no occlusion. The surgeon and surgical team were informed of the randomization, but teams taking care of the patient post-operatively including during long term follow-up, and who were charged with managing anti...
Source: Heart Rhythm - June 9, 2021 Category: Cardiology Authors: Erica S. Zado Source Type: research

EP News: Clinical
Kar et  al (Circulation April 6, 2021;Epub ahead of print, PMID XXXX) evaluated the WATCHMAN FLX left atrial appendage (LAA) closure device in patients in whom oral anticoagulation is indicated but are candidates for a nonpharmaceutical alternative in a prospective multicenter study. The primary safety en d point was the occurrence of one of the following events: death, ischemic stroke, systemic embolism, or device- or procedure-related events requiring cardiac surgery. The primary effectiveness end point was the incidence of effective LAA closure at 12-month follow-up.
Source: Heart Rhythm - May 3, 2021 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research

Blood biomarkers to detect new-onset atrial fibrillation and cardioembolism in ischemic stroke patients
Accumulating data suggest blood biomarkers could inform stroke etiology.
Source: Heart Rhythm - February 6, 2021 Category: Cardiology Authors: Dorin Harpaz, Ram Bajpai, Geelyn J.L. Ng, Michael Soljak, Robert S. Marks, Christine Cheung, Thiruma Valavan Arumugam, Amy M.L. Quek, Alfred I.Y. Tok, Raymond C.S. Seet Source Type: research

Predictors of ischemic stroke for low-risk patients with atrial fibrillation: A matched case-control study
The predictors of ischemic stroke in ‘low-risk’ patients with atrial fibrillation (AF) (CHA2DS2-VASc score 0 in men or 1 in women) are debated.
Source: Heart Rhythm - January 19, 2021 Category: Cardiology Authors: Soonil Kwon, Tae Jung Kim, Eue-Keun Choi, Hyo-Jeong Ahn, Euijae Lee, So-Ryoung Lee, Sang-Bae Ko, Seil Oh, Gregory Y.H. Lip Source Type: research