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Total 994 results found since Jan 2013.
Relationship between short telomere length and stroke: A meta-analysis
Background:
Several epidemiological studies had been carried out in different population cohorts to estimate the relationship between the shortened telomere length and stroke. However, the results still remained dispute. Consequently, we conducted this meta-analysis to estimate the relationship between them.
Methods:
PubMed, EMBASE, and Web of Science were systematically searched for related articles to evaluate the association between “stroke” and “telomere length. STATA 12.0 software was used to perform the meta-analysis. The Cochran Q test and inconsistency index (I2) were used to assess the heterogeneity. Be...
Source: Medicine - September 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Relationship between the anxiety/depression and care burden of the major caregiver of stroke patients
This study used a cross-sectional survey design and convenience sampling.
Totally, 117 caregivers of stroke patients were enrolled. Data were collected from questionnaires. Hamilton anxiety scale, Hamilton depression scale, and Zarit caregiver burden interview were performed. Multiple linear regression and correlation analysis were used.
The anxiety score, depression score and total burden score of 117 stroke caregivers were 16.56 ± 8.02, 18.63 ± 9.39, and 25.88 ± 10.35, respectively. Anxiety symptoms, mild to moderate depressive symptoms, and severe depressive symptoms were found in 43.9%, 26.5%, and 27.4...
Source: Medicine - October 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Association between the polymorphism (rs17222919, −1316T/G) of 5-lipoxygenase-activating protein gene (ALOX5AP) and the risk of stroke: A meta analysis
Conclusion:
This meta-analysis indicates that ALOX5AP-rs17222919-1316T/G may be a protective factor aginst stroke.
Source: Medicine - October 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Value of using the international classification of functioning, disability, and health for stroke rehabilitation assessment: A multicenter clinical study
This study aimed to evaluate the efficiency of the International Classification of Functioning, Disability, and Health (ICF) in stroke rehabilitation assessment in China and to identify correlations between the ICF and several commonly used clinical assessment instruments for stroke.
In total, 52 hospitals and 5 premier rehabilitation and neurology research centers participated in this cross-sectional multicenter clinical study. A total of 2822 stroke patients admitted to a neurology or rehabilitation department of a participating medical center between July 2012 and June 2014 were included. The ICF checklist contains 4 p...
Source: Medicine - October 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
A case report of left atrial myxoma-induced acute myocardial infarction and successive stroke
Rationale:
Left atrial myxoma is a common primary cardiac tumor, however, due to poor image quality or atypical myxoma images, it is often misdiagnosed by echocardiograph. A case of left atrial myxoma being misdiagnosed as a thrombus, which successively caused acute myocardial infarction (AMI) and stroke, is very rare. Contrast-enhanced echocardiography can play an important role in definitive diagnosis.
Patient concerns:
A 44-year-old woman was diagnosed AMI because of chest pain with no significant stenosis in the coronary arteries. One month later, the patient was suddenly found unconscious, magnetic resonance imag...
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Effectiveness and safety of Injinoryung-San-Gagambang (Yinchen Wuling powder) decoction on stroke patients with elevated serum liver enzymes: Three case reports
We present 3 cases of hepatic dysfunction caused by polypharmacy, one of which was a 51-year-old man with cerebellum infarction and pneumonia as a complication of stroke. He took multiple medications because of baseline diseases. After recurrence of pneumonia, his laboratory tests showed abnormal aminotransferase levels. Another patient was an 81-year-old woman with cerebral infarction at the right-middle cerebral artery. She was also taking>5 medications. Her laboratory tests conducted on admission showed abnormally elevated aminotransferase levels. The last patient was 77-year-old man with cerebral infarction at the left...
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Effect of hydrokinesitherapy on balance and walking ability in post-stroke patients: A systematic review protocol
Introduction:
Brain stroke is the second most common cause of death and major cause of disability in adults, representing a huge burden on patients and their families. Hydrokinesitherapy, a type of physical rehabilitation, may be beneficial to post-stroke recovery. We will systematically assess the clinical effectiveness and safety of hydrokinesitherapy for rehabilitation of stroke survivors in this review.
Methods:
We will perform a systematic search to identify all potentially relevant published studies on this topic. Online electronic databases including MEDLINE (via PubMed), EMBASE (via embase.com), Cochrane Centr...
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Traditional Chinese medicine for post-stroke depression: A systematic review and network meta-analysis (Protocol)
Conclusion:
Our study will generate evidence for TCM in the treatment of PSD and help to reduce the uncertainty about the effectiveness of PSD management, which will encourage further suggestions for TCM clinical practice or guideline.
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
The telomere length of peripheral blood cells is associated with the risk of ischemic stroke in Han population of northern China
This study was to investigate the relationship between telomere length and the incidence of ischemic stroke in Han population of northern China.
Methods:
In the present study, 152 patients with ischemic stroke were selected as the case group, and 152 healthy persons were used as the control group. Detection of telomere length was done by real-time polymerase chain reaction after extraction of genomic DNA from peripheral venous blood.
Results:
Our results showed that the telomere length of the patients in the case group was significantly lower than that of the control group (Z = −11.843, P
Source: Medicine - February 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
Effects of virtual reality immersive training with computerized cognitive training on cognitive function and activities of daily living performance in patients with acute stage stroke: A preliminary randomized controlled trial
Conclusion:
Virtual reality immersive training might be an affordable approach for cognitive function and activity of daily living performance recovery for patients with acute stroke.
Source: Medicine - March 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
Takotsubo cardiomyopathy associated with serotonin syndrome in a patient with stroke: A case report
We describe a patient with stroke who presented with TC caused by serotonin syndrome (SS) following the administration of serotonergic and dopaminergic agents.
Patient concerns:
A 55-year-old man with stroke was administered venlafaxine, tianeptine, ropinirole, carbidopa/levodopa, bromocriptine, and methylphenidate during rehabilitation. The patient presented with clinical features of SS (mental confusion, agitation, hyperhidrosis, chills, rigidity, and tachycardia), which persisted over 24 hours. The day after his SS symptoms disappeared, the patient's blood pressure decreased, and he developed tachycardia.
Diagnose...
Source: Medicine - March 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Effects of different interventions on animal models of ischemic stroke: Protocol for an overview and a network meta-analysis
Conclusion:
Our study can provide a reference for further clinical practice and can be compared with clinical trial results to obtain a more credible therapeutic effect of this intervention.
Ethics and communication:
Formal ethical approval is unnecessary, because this study is based on published researches.
PROSPERO registration number:
CRD42019126811
Source: Medicine - April 1, 2019 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Factors affecting the occurrence of gastrointestinal bleeding in acute ischemic stroke patients
In this study, we aimed to examine:
(1) the risk factors of GIB in acute cerebral infarction patients;
(2) association between GIB and 1-year mortality in patients with acute cerebral infarction.
Patients with acute cerebral infarction were divided into 2 groups based on the occurrence of GIB during acute stroke stage. Patient characteristics, clinical presentation, stroke risk factors, comorbidities, laboratory data, medication, and outcomes were investigated to analyze the associations between the variables and the probability of having GIB. In addition, patients in the study were matched individually by age, gender. ...
Source: Medicine - July 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Effect of 106PEAR1 and 168PTGS1 genetic polymorphisms on recurrent ischemic stroke in Chinese patient
This study was aimed to examine the relationships among the 106PEAR1 and 168PTGS1 polymorphisms and RIS.
This was a single-center, retrospective, case-control study of patients seen in consultation between March 2016 and December 2016 at the Shandong Provincial Hospital. The 106PEAR1 (G>A) and 168PTGS1 (−842A>G) polymorphisms were determined by fluorescence in situ hybridization.
There were 56 patients with RIS and 137 with initial stroke. Compared with the initial group, the RIS group showed lower LDL-C levels (P = .04). 168PTGS1 (−842A>G) did not meet the Hardy–Weinberg equilibrium. The AA genotype of the 106...
Source: Medicine - July 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Effects of Urinary Kallidinogenase on NIHSS score, mRS score, and fasting glucose levels in acute ischemic stroke patients with abnormal glucose metabolism: A prospective cohort study
This study evaluated the effect of urinary kallidinogenase on National Institute of Health Stroke Scale (NIHSS) score, modified Rankin scale (mRS) score, and fasting glucose levels in patients with acute ischemic stroke (AIS) combined with diabetes mellitus and impaired fasting glucose.
Patients with AIS and abnormal glucose metabolism were enrolled in this prospective cohort study and divided into 2 groups. The human urinary kallidinogenase (HUK) group were treated with urinary kallidinogenase and standard treatment; the control group received standard treatment. NIHSS scores, mRS scores, and fasting blood glucose were e...
Source: Medicine - August 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
