• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Left ventricular hypertrophy and left atrial size are associated with ischemic strokes among non-vitamin K antagonist oral anticoagulant users
ConclusionsPrior cerebrovascular events, diabetes, left ventricular hypertrophy, and increased left atrial size are risk factors for developing an IS among NOAC users.
Source: Journal of Neurology - August 7, 2023 Category: Neurology Source Type: research

Impacts of medication non-adherence to major modifiable stroke-related diseases on stroke prevention and mortality: a meta-analysis
ConclusionsNon-adherence to medications for the four stroke-related diseases contributes to the development of stroke and/or mortality in primary stroke prevention. More efforts are needed to improve patients ’ medication adherence.
Source: Journal of Neurology - February 27, 2023 Category: Neurology Source Type: research

White matter hyperintensities are an independent predictor of cognitive decline 3 years following first-ever stroke —results from the PROSCIS-B study
ConclusionHigher WMH burden was associated with a significant decline in cognition 3 years post-stroke in this cohort of first-ever stroke patients.
Source: Journal of Neurology - December 6, 2022 Category: Neurology Source Type: research

Clinical and neuroimaging risk factors associated with the development of intracerebral hemorrhage while taking direct oral anticoagulants
ConclusionsRisk factors including diabetes, prior stroke, and smoking history as well as MRI biomarkers including CMBs and cSS are associated with ICH in DOAC users. Although screening MRIs are not typically performed prior to initiating DOAC therapy, these data suggest that patients of high-hemorrhagic risk may be identified.
Source: Journal of Neurology - October 31, 2022 Category: Neurology Source Type: research

A score to predict the stroke recurrence of patients with embolic stroke of undetermined source
ConclusionThe developed score can improve risk stratification after ESUS in secondary care settings.
Source: Journal of Neurology - August 4, 2022 Category: Neurology Source Type: research

Prevalence and In-hospital outcomes of diabetes among acute ischemic stroke patients in china: results from the Chinese Stroke Center Alliance
ConclusionDiabetes was highly prevalent among AIS patients in China and associated with worse in-hospital outcomes. Greater efforts to increase targeted approach to secondary prevention treatments of diabetes in AIS patients are warranted.
Source: Journal of Neurology - May 5, 2022 Category: Neurology Source Type: research

Ischemic stroke associated with COVID-19: a systematic review and meta-analysis
ConclusionIschemic stroke caused by COVID-19 has its own unique clinical features. Although common high-risk factors can also be observed, its importance may have changed. The major inflammatory storm of COVID-19 is more likely to occur in male patients. The increase in the proportion of cryptogenic stroke has also made stroke related to COVID-19 complicated.
Source: Journal of Neurology - March 22, 2022 Category: Neurology Source Type: research

Time trends in stroke severity in the years 2005 to 2020: results from the Austrian Stroke Unit Registry
ConclusionDespite an aging population and generally increasing AF frequency, we observed a consistent trend towards less disabling strokes on admission.
Source: Journal of Neurology - March 21, 2022 Category: Neurology Source Type: research

Predictors and outcomes of ischemic stroke in reversible cerebral vasoconstriction syndrome
ConclusionIschemic stroke affects nearly 25% of patients with RCVS and is associated with adverse clinical outcomes. RCVS patients with cerebrovascular risk factors might have a higher predisposition for developing ischemic lesions during the disease process.
Source: Journal of Neurology - March 1, 2021 Category: Neurology Source Type: research

Targeting blood pressure for stroke prevention: current evidence and unanswered questions
This article aims to highlight current knowledge about BP control in stroke prevention and to provide new perspectives to be addressed in future studies so as to guide clinicians in their day-to-day practice.
Source: Journal of Neurology - February 27, 2021 Category: Neurology Source Type: research

Contribution of nuclear and mitochondrial gene mutations in mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome
ConclusionIndividuals with MELAS exhibit clinical phenotypes with varying degree of severity affecting multiple systems including auditory, visual, cardiovascular, endocrine, and nervous system. This is the first report to show that nuclear genetic factors influence the clinical outcomes/manifestations of MELAS subjects alone or in combination with m.3243A  >  G mutation.
Source: Journal of Neurology - January 23, 2021 Category: Neurology Source Type: research

Modern machine-learning can support diagnostic differentiation of central and peripheral acute vestibular disorders
ConclusionsEstablished clinical scores (such as HINTS) provide a valuable baseline assessment for stroke detection in acute vestibular syndromes. In addition, machine-learning methods may have the potential to increase sensitivity and selectivity in the establishment of a correct diagnosis.
Source: Journal of Neurology - June 10, 2020 Category: Neurology Source Type: research

GLP-1 receptor agonists in diabetes for stroke prevention: a systematic review and meta-analysis
ConclusionsAmong patients with type 2 DM,  GLP-1R agonists are beneficial for primary stroke, MACE, and cardiovascular mortality prevention. Further RCTs are needed to evaluate their role for secondary stroke prevention.
Source: Journal of Neurology - April 3, 2020 Category: Neurology Source Type: research

Ischemic stroke and dose adjustment of oral Factor Xa inhibitors in patients with atrial fibrillation
ConclusionOne in three patients with ischemic stroke during treatment with oral Xa inhibitors used inappropriate dose regimens. Underdosing was associated with lower functional plasma levels, higher clinical stroke severity and worse functional outcome.
Source: Journal of Neurology - March 22, 2020 Category: Neurology Source Type: research

Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study
ConclusionIschemic stroke subtypes differ between the two phenotypes. Diabetes and male sex have a stronger association with PCiS than ACiS. Definitive MRI-based PCiS diagnosis aids etiological investigation and contributes additional insights into specific risk factors and mechanisms of injury in PCiS.
Source: Journal of Neurology - November 10, 2019 Category: Neurology Source Type: research

Pages: 1  2