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Source: Neurology
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Total 104 results found since Jan 2013.
Assessment of Stroke Risk Factors in Southern Arizona (P02.054)
CONCLUSIONS: Despite a higher incidence of stroke, Hispanic concern regarding stroke risk factors is much lower than non-Hispanics. This suggests that knowledge linking risk factors for stroke and incident stroke may be lacking in Hispanic communities. Lessened concern regarding stroke risk factors may contribute to an increase incidence in stroke and to a worse outcome in this population. Hispanics increased interest in health promotion programs may afford one approach to addressing this problem. This data suggest that despite historically worse stroke outcomes, preventative efforts may be beneficial in raising stroke ris...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Nokes, B., Sim, Y., Byreddy, S., Chong, J., Drake, K., Labiner, D., Coull, B. Tags: P02 Cerebrovascular Disease II Source Type: research
A Novel Mutation in the Mitochondrial DNA Cytochrome B Gene (MTCYB) in a Patient with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke like Episodes Syndrome (P02.088)
CONCLUSIONS: This case demonstrates that MTCYB must be included in the already long list of mitochondrial DNA genes that have been associated with the MELAS phenotype.Supported by: Grant from the National Institutes of Health (HD32062) and by the Marriott Mitochondrial Disorder Clinical Research Fund (MMDCRF). PGR is supported by a postdoctoral fellowship from Ministerio de Educacion y Ciencia, Spain.Disclosure: Dr. Emmanuele has nothing to disclose. Dr. Sotiriou has nothing to disclose. Dr. Gutierrez Rios has nothing to disclose. Dr. Ganesh has nothing to disclose. Dr. Ichord has nothing to disclose. Dr. Foley has nothing...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Emmanuele, V., Sotiriou, E., Gutierrez Rios, P., Ganesh, J., Ichord, R., Foley, A. R., Akman, O., DiMauro, S. Tags: P02 Child Neurology I Source Type: research
Association of Slow Reaction Time with Future Risk of Parkinson's Disease in the Honolulu-Asia Aging Study (P03.063)
CONCLUSIONS: Men in the slowest quartile of SRT were significantly more likely to develop incident PD compared to those in the fastest quartile. Measurement of SRT is a low cost screening method that may help to identify those at risk for PD in later life.Supported by: National Institute on Aging Grant Nos. 1 U01 AG19349 and 5 R01 AG017155; and the Office of Research and Development, Department of Veterans Affairs.Disclosure: Dr. Ross has received research support from the Michael J. Fox Foundation. Dr. Inaba has nothing to disclose. Dr. Masaki has nothing to disclose. Dr. Abbott has nothing to disclose. Dr. Fong has nothi...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Ross, W., Inaba, M., Masaki, K., Abbott, R., Fong, K.-o., Bell, C., Petrovitch, H., Tanner, C., Launer, L., White, L. Tags: P03 Movement Disorders: Parkinson ' s Disease Epidemiology and Biomarkers Source Type: research
Defining the Border-Zone between Episodic Migraine (EM) and Chronic Migraine (CM): Medical Comorbidities in the US Population (P03.110)
CONCLUSIONS: The comorbidity profiles of HFEM have much more in common with CM than with LFEM suggesting that HFEM and CM may bear a close biological relationship.Supported by: The American Migraine Prevalence and Prevention Study is funded through a research grant to the National Headache Foundation from Ortho-McNeil Neurologics, Inc., Titusville, NJ. Additional analyses were supported by a grant from Allergan Inc., Irvine, CA, to the National Headache Foundation. Abstract development was conducted independent of financial support.Disclosure: Dr. Serrano has received research support from Allergan, ENDO Pharmaceuticals, M...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Serrano, D., Buse, D., Reed, M., Pavlovic, J., Vollbracht, S., Sollars, C. M., Lipton, R. Tags: P03 Headache: Epidemiology Source Type: research
Acute Basilar Artery Occlusion: Safety and Efficacy of Different Treatment Strategies and Predictors of Good Outcome (P01.228)
CONCLUSIONS: In the presented study, an apparent trend for better outcome was observed in the IVT+IAT group. Presence of arterial hypertension and severe stroke were identified as independent negative predictors of good outcome.Supported by: Grants of the Internal Grant Agency of Ministry of Health of the Czech Republic number NT/11386-5/2010, NT/11046-6/2010 and NT/13498-4/2012, and by the grant project number CZ.1.05/2.1.00/01.0030.Disclosure: Dr. Herzig has received personal compensation for activities with Bayer, Boehringer Ingelheim Pharmaceuticals, Inc., and Gedeon Richter. Dr. Dornak has nothing to disclose. Dr. Sko...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Herzig, R., Dornak, T., Skoloudik, D., Sanak, D., Kuliha, M., Roubec, M., Kocher, M., Prochazka, V., Kral, M., Veverka, T., Bartkova, A., Hlustik, P., Zapletalova, J., Herman, M., Kanovsky, P. Tags: P01 Cerebrovascular Disease I Source Type: research
Ischemic Stroke Related to Severe Iron-Deficiency Anemia in Adults May Benefit from Blood Transfusion (P01.232)
CONCLUSIONS: Prevalence of IDA is 1-20%; it is 3.9% in our AIS population and is often related to untreated uterine bleeding. As described in the pediatric population, severe IDA may be an underlying mechanism of ischemic stroke in adults, therefore, efforts must be undertaken to identify and treat the cause of the anemia. While patients with AIS and severe IDA may receive TPA, blood transfusion may be considered as an adjuvant therapy.Supported by: SPOTRIAS P50 NS044227 & NIH Training Grant 5T 32NS0077412-12.Disclosure: Dr. Choi has nothing to disclose. Dr. Sanchez-Rotunno has nothing to disclose. Dr. Gonzales has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Choi, E., Sanchez-Rotunno, M., Gonzales, N. Tags: P01 Cerebrovascular Disease I Source Type: research
Detection of Presymptomatically Latent Lesions Developing into Stroke-Like Episodes by Arterial Spin-Labeling Perfusion MRI in MELAS Patients (P03.162)
CONCLUSIONS: These findings suggest that regional ASL hyperperfusion in the presymptomatic phase precedes the appearance of upcoming stroke-like lesions, and that presymptomatic SEs had already occurred several months before the onset of clinical symptoms. ASL imaging has great potential for detecting presymptomatic stroke-like lesions and predicting the emergence of SEs.Supported by: In part by Grants-in-Aid for the Scientific Research on Innovative Areas from the Ministry of Education, Culture, Sports, Science and Technology of Japan and Young Scientists (B) from the Japan Society for the Promotion of Science, and the Re...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Ikawa, M., Kimura, H., Muramatsu, T., Matsunaga, A., Tsujikawa, T., Yamamoto, T., Kosaka, N., Kinoshita, K., Yamamura, O., Hamano, T., Nakamoto, Y., Yoneda, M. Tags: P03 Cerebrovascular Disease III Source Type: research
Quantitative Assessment of Corticospinal Tract Injury on Diffusion Tensor Imaging Correlates with Motor Outcome after Ischemic Stroke (P03.163)
CONCLUSIONS: The degree of CST involvement by ischemic stroke on DTT strongly correlates with the degree of motor impairment at each phase of ischemic stroke. The baseline FN predicts motor outcome. DTI-derived CST assessment could become a surrogate marker of motor impairment in the design of future restorative clinical trials.Supported by: 1) NIH-NINDS Grant R01 NS70922, 2) Mort and Brigitte Harris Stroke Fund.Disclosure: Dr. Maraka has nothing to disclose. Dr. Jiang has nothing to disclose. Dr. Jafari-Khouzani has nothing to disclose. Dr. Hamidian has nothing to disclose. Dr. Li has nothing to disclose. Dr. Malik has no...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Maraka, S., Jiang, Q., Jafari-Khouzani, K., Hamidian, N., Li, L., Malik, S., Zhang, T., Lu, M., Soltanian-Zadeh, H., Mitsias, P. Tags: P03 Cerebrovascular Disease III Source Type: research
Predictors of Good Clinical Outcome in Acute Stroke Patients Underwent Recanalization Therapy (P01.242)
CONCLUSIONS: NIHSS at admission, recanalization grade and early neurological improvement are independent predictors of clinical outcome in AIS patients underwent mechanical recanalization.Supported by: IGA MH CR grants NT/11386-5/2010, NT/11046-6/2010, NT/13498-4/2012.Disclosure: Dr. Skoloudik has nothing to disclose. Dr. Roubec has nothing to disclose. Dr. Kuliha has nothing to disclose. Dr. Herzig has received personal compensation for activities with Bayer, Boehringer Ingelheim Pharmaceuticals, Inc., and Gedeon Richter. Dr. Sanak has received personal compensation from Boehringer Ingelheim for serving on a scientific ad...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Skoloudik, D., Roubec, M., Kuliha, M., Herzig, R., Sanak, D., Prochazka, V., Hrbac, T. Tags: P01 Cerebrovascular Disease I Source Type: research
Diurnal Distribution of Patients Presenting at the Emergency Department with Acute Ischemic Stroke and Its Impact on Functional Outcome (P03.196)
CONCLUSIONS: A distinct diurnal pattern of ED arrival for acute ischemic stroke is observed with peak attendance in late morning. This was not associated with poorer functional outcome.Supported by: SingHealth Foundation Grant, National Neuroscience Institute, Singapore Health Services Pte Ltd.Disclosure: Dr. Tu has nothing to disclose. Dr. Tin has nothing to disclose. Dr. Oh has nothing to disclose. Dr. En has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Tu, T. M., Tin, A. S., Oh, H. C., En, L. Tags: P03 Cerebrovascular Disease III Source Type: research
Thrombolytic Utilization in Ischemic Stroke Is Significantly Higher in US Hospitals with Neurology Residency Program (S02.006)
CONCLUSIONS: Stroke care at NR hospitals is associated with an increased thrombolytic utilization rate. The increased tPA utilization at NR between 2002-2006 may be related to the rapid increase in Primary Stroke Centers across the country.Disclosure: Dr. Moradiya has nothing to disclose. Dr. Grant has nothing to disclose. Dr. Valsamis has nothing to disclose. Dr. Levine has received personal compensation in an editorical capacity for MEDLINK.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Moradiya, Y., Grant, J., Valsamis, H., Levine, S. Tags: S02 Acute Stroke Therapy Source Type: research
Predictors of Percutaneous Endoscopic Gastrostomy Tube Placement in Middle Cerebral Artery Acute Ischemic Stroke and Stroke Laterality (P02.018)
CONCLUSIONS: Our study indicates that high NIHSS on admission, aspiration pneumonia and inability to undergo first swallow evaluation are independent predictors of PEG placement in patients with acute MCA strokes. This knowledge can be used for early identification of patients that require PEG tube placement to provide prompt nutritional support.Supported by: Hartford Hospital Research Center grant.Disclosure: Dr. San Luis has nothing to disclose. Dr. McCullough has received personal compensation for activities with Genentech, Inc. Dr. Ollenschleger has nothing to disclose. Dr. Staff has nothing to disclose. Dr. Fortunato ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: San Luis, C., McCullough, L., Ollenschleger, M., Staff, I., Fortunato, G. Tags: P02 Cerebrovascular Disease II Source Type: research
Cystatin C as a Marker of Degeneration in Multiple Sclerosis (P03.241)
CONCLUSIONS: Cystatin C concentration decrease in RR form of MS could give evidence for high disease activity in this stage of the disease with high myelin damage and neurodegeneration.Supported by: Grant IGA MHCZ NT 12221-5/2010.Disclosure: Dr. Prikrylová Vranová has nothing to disclose. Dr. Sládková has nothing to disclose. Dr. Mares has nothing to disclose. Dr. Hlustík has nothing to disclose. Dr. Langová has nothing to disclose. Dr. Kanovsky has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Prikrylova Vranova, H., Sladkova, V., Mares, J., Hlustik, P., Langova, J., Kanovsky, P. Tags: P03 Multiple Sclerosis: Disease Biomarkers Source Type: research
Infantile Encephaloneuromyopathy and Defective Mitochondrial Translation Are Due to a Homozygous RMND1 Mutation (P03.010)
CONCLUSIONS: We identified the first human mutation affecting a DUF155 protein in a family with a severe autosomal-recessive mitochondrial translation defect. Further studies are necessary to understand the function of RMND1 and its role in mitochondrial protein synthesis.Supported by: Partially supported by the Marriott Mitochondrial Disorder Clinical Research Fund. C.M.Q. is supported by National Institute of Health (NIH) grant K23 HD065871 from the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD). M.H. is supported by NIH grants R01 HD057543 and R01 HD056103 from the NICHD and th...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Garcia-Diaz, B., Barros, M., Sanna-Cherchi, S., Emmanuele, V., Akman, H. O., Ferreiro-Barros, C., Horvath, R., Tadesse, S., El Gharaby, N., DiMauro, S., De Vivo, D., Shokr, A., Hirano, M., Quinzii, C. Tags: P03 Child Neurology II Source Type: research
