Filtered By:
Source: Neurology
Education: Grants

This page shows you your search results in order of date. This is page number 6.

Order by Relevance | Date

Total 104 results found since Jan 2013.

Cholesterol, Statins and the Risk of Dementia in the Oldest-Old: The 90+ Study (S58.003)
CONCLUSIONS: Contrary to studies reporting that high cholesterol is associated with decreased dementia in the oldest-old, we report that hypercholesterolemia was not associated with dementia while statin users were at decreased dementia risk. There are a variety of mechanisms by which statins may be neuroprotective including effects on amyloid production, neurofibrillary tangles, secondary stroke prevention, and other anti-inflammatory pleiotropic effects. Additional research is needed to explore other potential explanations for our results along with assessment of the effect of serum cholesterol levels and statin lipophil...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Evans, M., Kawas, C., Corrada, M. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Clinical Aspects Source Type: research

Antiphospholipid Antibodies, Brain Infarcts, And Cognitive And Motor Decline In Aging (ABICMA): Final Cerebral Infarct Results from a Community-Based, Longitudinal, Clinical-Pathological Study (S62.002)
CONCLUSIONS: Overall aPL+ at baseline, proximal to death, or persistent aPL+ are not independent risk factors for BI in the elderly.Study Supported by: NIH grants R01HL96944, R01AG040039, P30AG10161, R01AG15819, R01AG17917, R01 AG24480Disclosure: Dr. Levine has received personal compensation in an editorial capacity for MedLink. Dr. Levine has received royalty payments as editor of a book. Dr. Arvanitakis has received personal compensation for activities with Vista Health. Dr. Arvanitakis has received research support from Ceregene, Inc. Dr. Brey has received personal compensation in an editorial capacity for Neurology Now...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Levine, S., Arvanitakis, Z., Brey, R., Rand, J., Schneider, J., Yu, L., Leurgans, S., Bennett, D. Tags: Cerebrovascular Disease and Interventional Neurology: Cognitive and Behavioral Source Type: research

Testing the Presumption of Consent to Emergency Thrombolysis for Stroke (S35.005)
CONCLUSIONS: The proportion of older adults who would want emergency thrombolysis is comparable to the proportion who would want emergency CPR, and is unaffected by the inability to obtain informed consent.Study Supported by: National Institute on Aging (K23AG043553), National Center for Advancing Translational Sciences (KL2TR000143), and the American Brain Foundation Clinical Research Training Fellowship Program. Data collection was provided by Time-sharing Experiments in the Social Sciences, NSF Grant 0818839.Disclosure: Dr. Chiong has nothing to disclose. Dr. Kim has received research support from SanBio, Inc. Dr. Huang...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chiong, W., Kim, A., Huang, I., Farahany, N., Josephson, S. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Treatment Source Type: research

Prehospital Factors Associated with Stroke Misdiagnosis by EMS Providers (S35.006)
Conclusions: LICH EMS providers missed 41% of strokes and our findings suggest that greater clinical suspicion for stroke should be exercised in patients who have a higher prehospital systolic blood pressure, who have a dispatch call of stroke, past medical history of diabetes or stroke and in those who are unconscious.Study support: NIH grants 1U01NS044364, R01 HL096944, 1U10NS077378 and 1U10NS080377.Disclosure: Dr. Brandler has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Helzner has nothing to disclose. Dr. Levine has received personal compensation in an editorial capacity for MedLink. Dr. Levine has rec...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Brandler, E., Sharma, M., Helzner, E., Levine, S. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Treatment Source Type: research

Randomized Controlled Trial of CI Therapy for Progressive MS: Increased Real-World Function and Neuroplasticity on MRI (I7-1.008)
CONCLUSIONS: CI therapy appears to be efficacious for improving real-world arm use in progressive hemiparetic MS and significantly increases cortical grey matter structural plasticity. Together, these findings suggest that CI therapy, but not CAM, can counteract the progressive functional loss and CNS degeneration of progressive MS.Supported by: National MS Society grant RG 4221 and NIH grant HD061767.Disclosure: Dr. Mark has nothing to disclose. Dr. Taub has nothing to disclose. Dr. Uswatte has nothing to disclose. Dr. Cutter has received personal compensation for activities with Sanofi-Aventis Pharmaceuticals Inc., Cleve...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Mark, V., Taub, E., Uswatte, G., Cutter, G., Morris, D., McKay, S., Bowman, M., Haddad, M., Rickards, T., Sterling, C. Tags: Emerging Therapeutic Advances in Multiple Sclerosis Poster Presentations Source Type: research

Intermittent Temporal Slowing in Cognitively Normal Oldest-old: The 90+ EEG Study (P3.214)
CONCLUSIONS: In this preliminary study, asymptomatic ITS was not associated with subsequent cognitive decline in healthy oldest-old participants. ITS may represent a benign, aging phenomenon, as opposed to an underlying pathological process, and may not require further clinical work-up in the oldest-old. However, the small sample size limits our statistical power and the results warrant a larger study to confirm the findings.Study supported by: NIH grants T32NS045540 and R01AG21055 Disclosure: Dr. Bullain has nothing to disclose. Dr. Corrada has nothing to disclose. Dr. Greenia has nothing to disclose. Dr. ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bullain, S., Corrada, M., Greenia, D., Kawas, C. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Clinical Aspects Source Type: research

The Relationship Between Vitamin D Concentrations and Leg Strength in Persons with Parkinson's (P2.054)
CONCLUSION: Our data does not indicate that lower vitamin D levels are associated with reduced muscle strength; there were non-significant trends to suggest the opposite. These results may be spurious or there may be a different relationship in persons with PD. Mechanisms beyond strength such as central balance control, changes in gait patterns, and cognitive function are necessary to include in intervention studies of vitamin D and balance/falls.Study Supported by: Department of Veterans Affairs CDA2 Award, OCTRI - grant number UL1 RR024140; NeuroNext (5U10NS077350-02).Disclosure: Dr. Peterson has nothing to disclose. Dr....
Source: Neurology - April 9, 2014 Category: Neurology Authors: Peterson, A., Lobb, B., Murchison, C., Quinn, J. Tags: Movement Disorders: Co-morbidities and Novel Care Models Source Type: research

Ascertainment of Stroke Incidence among Alaskan Native Populations, 2005-2009: The Alaska Native Stroke Registry (S12.001)
CONCLUSIONS: In one of the first ever stroke incidence studies in Alaska Native populations we report high rates of stroke overall and by stroke subtype in both urban and rural communities.Study Supported by: NINDS grant 3U01NS048069-04S3Disclosure: Dr. Boden-Albala has received personal compensation for activities with the Desmoteplase Advisory Committee. Dr. Roberts has nothing to disclose. Dr. Allen has nothing to disclose. Dr. Bulkow has nothing to disclose. Dr. Trimble has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Boden-Albala, B., Roberts, E., Allen, J., Bulkow, L., Trimble, B. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors Source Type: research

Visit-to-visit Systolic Blood Pressure Variability Predicts All-Cause and Cardiovascular Mortality after Lacunar Infarct (P6.274)
CONCLUSIONS: Visit-to-visit systolic BPV predicts long-term all-cause and cardiovascular mortality after lacunar infarct, independent of conventional risk factors including average BP control.Study Supported by: RGC Direct Allocation Grant of The University of Hong KongDisclosure: Dr. Lau has nothing to disclose. Dr. Wong has nothing to disclose. Dr. Chang has nothing to disclose. Dr. Teo has nothing to disclose. Dr. Hon has nothing to disclose. Dr. Chan has received research support from Bayer Pharmaceuticals Corporation, and Merck & Co. Inc. Dr. Wat has nothing to disclose. Dr. Cheung has nothing to disclose. Dr. Li ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Lau, G., Wong, Y. K., Chang, R., Teo, K., Hon, S., Chan, K., Wat, K., Cheung, R., Li, L., Siu, D., Ho, S. L., Tse, H. F. Tags: Cerebrovascular Disease and Interventional Neurology: Risk Factors Source Type: research

Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients during Head of Bed Manipulation (P4.216)
CONCLUSIONS: A lower HOB angle results in an increase in cortical CBF without a significant change in arterial flow velocity in the setting of acute stroke, but there is variability across patients in this response. Bedside CBF monitoring with DCS provides a potential means to individualize interventions designed to optimize CBF in acute ischemic stroke.Disclosure: Dr. Favilla has nothing to disclose. Dr. Mesquita has nothing to disclose. Dr. Mullen has nothing to disclose. Dr. Durduran has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Minkoff has nothing to disclose. Dr. Kasner has received personal compensati...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Favilla, C., Mesquita, R., Mullen, M., Durduran, T., Kim, M., Minkoff, D., Kasner, S., Joel, G., Yodh, A., Detre, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

Endovascular Treatment of Acute Basilar Artery Occlusion (P4.217)
CONCLUSIONS: Data in this series showed that multimodal EVT was an effective recanalization method of acute BAO. Bridging therapy was associated with better 30-day clinical outcome. EVT should be started as soon as possible after IVT and not considered only as a rescue strategy. Study Supported by: the grants of the Internal Grant Agency of Ministry of Health of the Czech Republic number NT/11046-6/2010, NT/11386-5/2010, and NT/13498-4/2012, and by the grant project number CZ.1.05/2.1.00/01.0030.Disclosure: Dr. Herzig has received personal compensation for activities with Bayer Pharmaceuticals Corp., and Gedeon Richter. Dr...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Herzig, R., Dornak, T., Skoloudik, D., Sanak, D., Kuliha, M., Roubec, M., Havlicek, R., Hajdukova, L., Kocher, M., Prochazka, V., Lacman, J., Charvat, F., Kral, M., Veverka, T., Zapletalova, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

Safety of tPA + Transcranial Emission of Low-Energy Lasers for Acute Stroke Recovery - Results (P4.219)
Conclusion: Transcranial Laser in this small exploratory study was well tolerated in combination with IV tPA. Larger studies are needed to explore if the combination of LASER therapy plus tPA is safe and shows better outcome than IV tPA alone.Study supported by NIH Grant P50 NS044148Clinical Trial Registry: NCT01220739Disclosure: Dr. Hemmen has nothing to disclose. Dr. Raman has nothing to disclose. Dr. Sen has received personal compensation for activities with Genentech Inc., Sanofi Aventis Pharmaceutical Inc., Bristol-Myers Squibb Co., and Boehringer Ingelheim Pharmaceuticals Inc. Dr. Sen has received research support fr...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hemmen, T., Raman, R., Sen, S., Geraghty, M., Rapp, K., Richeri, S., Meyer, B., Zivin, J., Fanale, C. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Thrombolysis Source Type: research

Randomized Controlled Trial of CI Therapy for Progressive MS: Increased Real-World Function and Neuroplasticity on MRI (S23.007)
CONCLUSIONS: CI therapy appears to be efficacious for improving real-world arm use in progressive hemiparetic MS and significantly increases cortical grey matter structural plasticity. Together, these findings suggest that CI therapy, but not CAM, can counteract the progressive functional loss and CNS degeneration of progressive MS.Supported by: National MS Society grant RG 4221 and NIH grant HD061767.Disclosure: Dr. Mark has nothing to disclose. Dr. Taub has nothing to disclose. Dr. Uswatte has nothing to disclose. Dr. Cutter has received personal compensation for activities with Sanofi-Aventis Pharmaceuticals Inc., Cleve...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Mark, V., Taub, E., Uswatte, G., Cutter, G., Morris, D., McKay, S., Bowman, M., Haddad, M., Rickards, T., Sterling, C. Tags: MS and CNS Inflammatory Disease: Novel Therapeutics Source Type: research

Nonverbal Oral Apraxia in Primary Progressive Aphasia and Apraxia of Speech (P2.166)
CONCLUSIONS:We have shown that AOS, NVOA and IMA are at least partially distinct among patients with PPA and PPAOS. NVOA might be more common in patients with AOS due to the proximity of the region we identified by VBM to the premotor area, which has been implicated in AOS. The association of IMA and NVOA among patients without AOS could represent disruption of a module shared by nonverbal oral movements and limb movements.Study Supported by: NIH grant R01-DC010367Disclosure: Dr. Botha has nothing to disclose. Dr. Duffy has nothing to disclose. Dr. Strand has nothing to disclose. Dr. Whitwell has nothing to disclose. Dr. J...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Botha, H., Duffy, J., Strand, E., Whitwell, J., Josephs, K. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: General Cognition Source Type: research

Trends in Substance Abuse Preceding Stroke in Young Adults: An Update (S55.004)
Conclusions: Substance abuse is an important and highly prevalent risk factor for stroke in young adults. More efforts are needed to curb the increasing relationship between stroke in young adults and illicit drugs, alcohol, and smoking.Study supported by: NIH NINDS grant R01 NS30678Disclosure: Dr. De Los Rios La Rosa has nothing to disclose. Dr. Kleindorfer has received personal compensation for activities with Genentech, Inc. and for medicolegal case review. Dr. Khoury has nothing to disclose. Dr. Broderick has received research support from Significant, Genentech Inc., and Schering-Plough Corporation, and the National I...
Source: Neurology - April 9, 2014 Category: Neurology Authors: De Los Rios La Rosa, F., Kleindorfer, D., Khoury, J., Broderick, J., Alwell, K., Moomaw, C., Khatri, P., Adeoye, O., Flaherty, M., Woo, D., Eilerman, J., Ferioli, S., Kissela, B. Tags: Pediatric Stroke and Stroke in the Young Source Type: research