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Source: Neurology
Condition: Disability

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Total 221 results found since Jan 2013.

Expanding antiplatelet use for patients with stroke: The case for stroke of unknown type
Stroke occurs in approximately 16.9 million people worldwide annually.1 It is the second cause of death2 and the third leading cause of disability-adjusted life-years lost to disease.3 The greatest burden is in low and middle income countries (LMIC), where approximately 69% of these strokes occur.1
Source: Neurology - August 25, 2014 Category: Neurology Authors: Thrift, A. G., de los Rios, F. Tags: Decision analysis, All Cerebrovascular disease/Stroke, Intracerebral hemorrhage EDITORIALS Source Type: research

Neurology's stake in foundational neuroscience research
The NIH mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. For over a decade, the National Institute of Neurological Disorders and Stroke (NINDS) mission statement focused on reducing the burden of illness due to neurologic disorders. While the need for basic research as part of this mission was always implicit, a recently released analysis of NINDS grant applications convinced leadership to make it explicit by adding "advancing fundamental understanding of the nervous system" to ...
Source: Neurology - August 18, 2014 Category: Neurology Authors: Koroshetz, W. J., Landis, S. Tags: EDITORIALS Source Type: research

Outcome after surgical or conservative management of cerebral cavernous malformations
Conclusions: CCM excision was associated with worse outcomes over 5 years compared to conservative management. Long-term follow-up will determine whether this difference is sustained over patients' lifetimes. Meanwhile, a randomized controlled trial appears justified. Classification of evidence: This study provides Class III evidence that CCM excision worsens short-term disability scores and increases the risk of symptomatic intracranial hemorrhage and new focal neurologic deficits.
Source: Neurology - August 11, 2014 Category: Neurology Authors: Moultrie, F., Horne, M. A., Josephson, C. B., Hall, J. M., Counsell, C. E., Bhattacharya, J. J., Papanastassiou, V., Sellar, R. J., Warlow, C. P., Murray, G. D., Al-Shahi Salman, R., On behalf of the Scottish Audit of Intracranial Vascular Malformations ( Tags: Stroke in young adults, Clinical trials Systematic review/meta analysis, Clinical trials Observational study (Cohort, Case control), Cohort studies, Intracerebral hemorrhage ARTICLE Source Type: research

Racial differences and disability after stroke
In their article "Racial differences in disability after stroke: Results from a nationwide study," Burke and colleagues1 tried to better understand how race might affect recovery after a stroke. The problem of stroke is large: about 7,000,000 people in the United States are survivors of stroke. That number is getting bigger. Stroke is a problem that mainly affects older individuals. As the US population ages, there will be more people at risk for stroke. In addition, modern medical care has reduced the risk of dying from a stroke, meaning that there will be more survivors of this serious medical illness.
Source: Neurology - July 28, 2014 Category: Neurology Authors: Karceski, S. Tags: Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke PATIENT PAGES Source Type: research

Racial disparities in long-term stroke outcomes: Evidence from nationwide epidemiologic studies
It is often said that stroke is a leading cause of long-term disability, especially in older adults.1 The increasing size of the older adult population and the higher percentage of stroke patients surviving the acute hospitalization stage predict a doubling of the number of stroke survivors living with disabilities in the community over the next few decades.1,2 Numerous studies have identified race or ethnic disparities in stroke incidence, mortality, and functional outcomes, with African Americans often having worse outcomes, on average, when compared to white stroke survivors.3,4 Some investigations have also reported se...
Source: Neurology - July 28, 2014 Category: Neurology Authors: Roth, D. L., Dhamoon, M. S. Tags: EDITORIALS Source Type: research

Racial differences in disability after stroke: Results from a nationwide study
Conclusion: After stroke, black individuals have a greater prevalence of activity limitations than white individuals, largely due to their greater physical capacity limitations. Further understanding of the causes of racial differences in capacity after stroke is needed to reduce activity limitations after stroke and decrease racial disparities.
Source: Neurology - July 28, 2014 Category: Neurology Authors: Burke, J. F., Freedman, V. A., Lisabeth, L. D., Brown, D. L., Haggins, A., Skolarus, L. E. Tags: Outcome research, All Cerebrovascular disease/Stroke, All Rehabilitation ARTICLE Source Type: research

The global burden of neurologic diseases
WHO categorizes causes of death and disability into (1) communicable diseases, maternal and perinatal conditions, and nutritional deficiencies; (2) non-communicable diseases (NCD); and (3) injuries. NCD are the leading cause of death and disability globally and are rising as a result of demographic and epidemiologic changes occurring in both developed and developing countries.1,2 Increasing life expectancies, unhealthy diet, physical inactivity, tobacco use, and harmful use of alcohol contribute to the growing incidence and prevalence of NCD, such as heart disease, stroke, diabetes, cancers, and chronic respiratory disease...
Source: Neurology - July 21, 2014 Category: Neurology Authors: Chin, J. H., Vora, N. Tags: All Cerebrovascular disease/Stroke, All epidemiology, All Epilepsy/Seizures GLOBAL PERSPECTIVES Source Type: research

Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Gaze Deviation in Acute Stroke: Neuroimaging Evidence, Significance and Clinical Correlation (P1.132)
CONCLUSIONS: In this stroke code cohort, DeyeCOM sign correlates with a diagnosis of stroke, and suggests value to all physicians involved in diagnosis and treatment of acute stroke.Disclosure: Dr. Herial has nothing to disclose. Dr. Raman has nothing to disclose. Dr. Ernstrom has nothing to disclose. Dr. Coffman has nothing to disclose. Dr. Schlick has nothing to disclose. Dr. Rapp has nothing to disclose. Dr. Modir has nothing to disclose. Dr. Meyer has nothing to disclose. Dr. Hemmen has nothing to disclose. Dr. Meyer has received personal compensation for activities with The Medicine's Company as a speaker and advisory...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Herial, N., Raman, R., Ernstrom, K., Coffman, C., Schlick, K., Rapp, K., Modir, R., Meyer, D., Hemmen, T., Meyer, B. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Miscellaneous Source Type: research

Development of National Web-based Registry for Acute Stroke (P1.133)
CONCLUSIONS: It is hoped that the ASR will provide extensive clinical information on all acute stroke patients admitted into the HMC system. Using this information, we hope to be able to determine the trends and the relative frequency of specific disease manifestations in Qatar. We also hope that this information will stimulate other hospitals within the region to examine their management routines and thereby serve as a basis for improvements in patient care across the Middle East.Disclosure: Dr. Streletz has nothing to disclose. Dr. Akhtar has nothing to disclose. Dr. Kamran has nothing to disclose. Dr. Deleu has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Streletz, L. J., Akhtar, N., Kamran, S., Deleu, D. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Miscellaneous Source Type: research

Factors Influencing Self-Perception of Recovery from Stroke in Comparison to Objective Assessments (P1.137)
CONCLUSIONS: Among individuals with minimum post-stroke disability, patient perception of degree of global recovery is strongly influenced by degree of minor residual symptoms and minimum disability. For similar disability levels, lesser degree of recovery is perceived by individuals who are younger, are male, and are of Hispanic ethnicity.Study Supported by: NIH/NINDSDisclosure: Dr. Hodgson has nothing to disclose. Dr. Sanoff has nothing to disclose. Dr. Devereux has nothing to disclose. Dr. Feudi has nothing to disclose. Dr. Cherin has nothing to disclose. Dr. Chatfield has nothing to disclose. Dr. Conwit has nothing to ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hodgson, T. K., Sanoff, R., Devereux, G., Feudi, S., Cherin, S., Chatfield, F., Conwit, R., Hamilton, S., Sanossian, N., Starkman, S., Saver, J. Tags: Cerebrovascular Disease and Interventional Neurology: Rehabilitation and Recovery Source Type: research

Does Abnormal Blood Platelet Count Influence Mortality, Impairment and Disability After Acute Ischemic Stroke? (P1.141)
Withdrawn by Author
Source: Neurology - April 9, 2014 Category: Neurology Authors: Furlan, J., Fang, J., Silver, F. Tags: Cerebrovascular Disease and Interventional Neurology: Rehabilitation and Recovery Source Type: research

Long Term Stroke Recurrence in Patients with Basilar Artery Occlusion. (P1.153)
CONCLUSIONS:The long-term rate of recurrent cerebrovascular events in our cohort of patients with BAO was 31.5%, with ischemic stroke involving the posterior circulation being the most common.Study Supported by:Disclosure: Dr. Ruff has nothing to disclose. Dr. Burrus has nothing to disclose. Dr. Rabinstein has received royalty payments from Elsevier and Oxford. Dr. Rabinstein has received research support from DJO Global.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ruff, M., Burrus, T., Rabinstein, A. Tags: Cerebrovascular Disease and Interventional Neurology: Intracranial Disease Source Type: research

Neuro-QOL for Assessment of Cognitive Impairment after Stroke: Comparison with Modified Rankin Scale (P2.116)
CONCLUSIONS: The mRS correlates modestly but non-linearly with patient-reported scores of cognitive function using Neuro-QOL. Some patients report impairments in cognitive function despite no disability by mRS (i.e. 0-1). Therefore, Neuro-QOL provides a complementary tool for assessment of cognitive function after stroke.Disclosure: Dr. Sangha has nothing to disclose. Dr. Corado has nothing to disclose. Dr. Bergman has nothing to disclose. Dr. Naidech has received research support from Gaymar Inc. Dr. Cella has received personal compensation for activities with Moffit Caner Center. Dr. Bernstein has received personal compe...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Sangha, R., Corado, C., Bergman, D., Naidech, A., Cella, D., Bernstein, R., Curran, Y., Prabhakaran, S. Tags: Cerebrovascular Disease and Interventional Neurology: Behavioral, Cognitive, and Miscellaneous Source Type: research

Gender Differences in Primary Stroke Center Evaluation and Utilization of rt-PA (P2.133)
CONCLUSIONS:Among women, PSCs utilize more rt-PA than non-PSCs. The increased utilization of rt-PA at PSCs is consistent between men and women and stable across racial and ethnic groups. Despite this a lower proportion of women receive rt-PA than men.Study Supported by:R01 HS018362-01A1 AHRQDisclosure: Dr. Mullen has nothing to disclose. Dr. Albright has received research support from The Agency for Healthcare Research and Quality, and the National Institute on Minority Health and Health Disparities. Dr. Boehme has nothing to disclose. Dr. Kasner has received personal compensation for activities with Pfizer Inc, Novartis, ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Mullen, M., Albright, K., Boehme, A., Kasner, S., Kallan, M., Branas, C., Carr, B. Tags: Cerebrovascular Disease and Interventional Neurology: Evaluation, Cost, and Quality Source Type: research