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Source: Neurology
Condition: Thrombosis

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Total 223 results found since Jan 2013.

An Unusual Cause Of Recurrent Ischemic Stroke: Trousseau's Syndrome From Gastric Cancer (P4.231)
CONCLUSIONS: Trousseau’s Syndrome must be considered in those presenting with recurrent strokes with an otherwise negative embolic work up especially in the elderly and those with cancer risk factors. It must prompt the clinician to look for an associated malignancy.Disclosure: Dr. JADEJA has nothing to disclose. Dr. Johnson has nothing to disclose. Dr. Soetanto has nothing to disclose. Dr. Nalleballe has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Graber has received personal compensation for activities with Stemedica Inc., Novocure Inc., and Biogen Idec.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jadeja, N., Johnson, J., Soetanto, A., Nalleballe, K., DeNiro, L., Qureshi, I., Graber, J. Tags: Neuro-oncology: Paraneoplastic Disorders Source Type: research

Stroke in a Young Woman Caused by Carotid Web (P1.024)
CONCLUSIONS: A carotid web increases stroke risk through thromboembolism. Unlike in other forms of carotid FMD, endarterectomy removes the focus of thrombosis without need for anticoagulation. Alternatively, anticoagulation or antiplatelet therapy might decrease stroke risk but would burden a young patient with increased lifetime risk of bleeding. Study Supported by: N/ADisclosure: Dr. Petrsoric has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Labovitz has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Petrsoric, J., DeNiro, L., Labovitz, D. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Mechanisms and Outcomes of Ischemic Stroke in Pregnancy and Postpartum: A Retrospective Cross-Sectional Study (P3.070)
CONCLUSIONS: Women with pregnancy-associated ischemic strokes were younger and had fewer vascular risk factors when compared with other young women with ischemic strokes. Outcomes were similar in the two groups, with a substantial proportion of poor outcomes in both groups. Our results are limited by the small sample size and retrospective nature of the study. Larger studies are needed to better characterize the pathophysiology of pregnancy-associated stroke.Disclosure: Dr. Miller has nothing to disclose. Dr. Yaghi has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Willey has nothing to disclose. Dr. Elkind h...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Miller, E., Yaghi, S., Boehme, A., Willey, J., Elkind, M., Marshall, R. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Transient Neurologic Deficit Presenting with Cortical Vein Thrombosis Caused by Intracranial Hypotension: Case Report (P1.028)
CONCLUSION We hypothesized that intracranial hypotension led to venous engorgement (based on the Monroe-Kelli doctrine) and the subsequent cortical vein thrombosis, which then produced vasogenic edema, cortical irritability, and focal seizure that mimicked ischemic stroke. Based on our findings, clinicians should consider intracranial hypotension in patients presenting with dural sinus or cortical vein thrombosis, and orthostatic headache or imaging findings of dural enhancement.Disclosure: Dr. Plancher has nothing to disclose. Dr. Flaherty has received personal compensation for activities with CSL Behring as a consultant ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Plancher, J. M.-O., Flaherty, M. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Embolic stroke with spontaneous recanalization (P3.085)
Conclusions This study infers that thrombolysis remarkably improves clinical outcome in patients with embolic stroke who do not have visible arterial occlusion at presentation. A prospective study to validate these results is being planned.Disclosure: Dr. Lahoti has nothing to disclose. Dr. Gokhale has nothing to disclose. Dr. Caplan has received personal compensation in an editorial capacity for JAMA Neurology. Dr. Michel has received personal compensation for activities with Servier, Sanofi-Aventis Pharmaceuticals, and Boehringer Ingelheim Pharmaceuticals, as a speaker, steering committee member, and/or advisory board me...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lahoti, S., Gokhale, S., Caplan, L., Michel, P., Samson, Y., Rosso, C., Limaye, K., Hinduja, A., Singhal, A., Ali, S., Kryscio, R., Dedhia, N., Hastak, S., Liebeskind, D., Pettigrew, L. Tags: Cerebrovascular Disease and Interventional Neurology: Hemorrhagic and Ischemic Stroke Source Type: research

Pineal Apoplexy With Cerebral Infarction (P1.033)
CONCLUSIONS:Although it appears that the infarcts were caused by the apoplexy due to their temporal progression, we conclude that pineal apoplexy was unlikely to cause the patient’s stroke and that the potential culprit of both events was a proximal source such as a cardiac or aortic thromboembolism.Disclosure: Dr. Truong has nothing to disclose. Dr. Young has nothing to disclose. Dr. Naderi has nothing to disclose. Dr. Brizuela has nothing to disclose. Dr. Handwerker has nothing to disclose. Dr. Al-Khoury has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Truong, A., Young, M., Naderi, N., Brizuela, A., Handwerker, J., Al-Khoury, L. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Early Dramatic Recovery after Endovascular Reperfusion in Acute Ischemic Stroke (P4.290)
Conclusion: Early dramatic recovery after endovascular reperfusion of large vessel AIS is not uncommon. Lower NIHSS should not necessarily exclude patients from the possibility of IAT. Age and procedural time have a critical importance in the management of large vessel AIS patients.Disclosure: Dr. Lima has nothing to disclose. Dr. Haussen has nothing to disclose. Dr. Belagaje has nothing to disclose. Dr. Anderson has nothing to disclose. Dr. Nahab has nothing to disclose. Dr. Rangaraju has nothing to disclose. Dr. Frankel has nothing to disclose. Dr. Nogueira has received personal compensation for activities with Concentri...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lima, A., Haussen, D., Belagaje, S., Anderson, A., Nahab, F., Rangaraju, S., Frankel, M., Nogueira, R. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Treatment Source Type: research

Extensive Workup for Embolic Sources in Lacunar Strokes: Prevalence in an Academic Setting (P1.043)
CONCLUSIONS: Lacunar strokes represent a substantial fraction of the ischemic strokes admitted in this urban hospital setting. These patients typically receive extensive work-up for thromboembolic sources similar to that applied to large artery strokes. Examination of clinical features and outcomes of lacunar stroke, and of the clinical utility of the extensive imaging, is warranted to guide best clinical practices.Disclosure: Dr. Wang has nothing to disclose. Dr. Choi has nothing to disclose. Dr. Gallardo has nothing to disclose. Dr. Nwaneri has nothing to disclose. Dr. Brorson has received personal compensation for activ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Wang, Y., Choi, Y., Gallardo, J., Nwaneri, I., Brorson, J. Tags: Cerebrovascular Disease and Interventional Neurology: The Spectrum of Small Vessel Cerebrovascular Disease Source Type: research

Methotrexate Encephalopathy as a Cause of Alternating Hemiplegia (P3.143)
CONCLUSIONS: Transient neurologic dysfunction with reversible MRI abnormality is a recognized consequence of intrathecal methotrexate chemotherapy in childhood ALL. Patients present with dramatic fluctuating neurologic symptoms with associated MRI changes and may be mistaken for stroke or a seizure disorder. Once the syndrome is recognized patients typically recover with supportive management and rehabilitation.Disclosure: Dr. Sullivan has nothing to disclose. Dr. Quealy has nothing to disclose. Dr. Olsevskaite has nothing to disclose. Dr. MacEneaney has nothing to disclose. Dr. Ryan has nothing to disclose. Dr. O'Toole ha...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Sullivan, C., Quealy, J., Olsevskaite, J., MacEneaney, P., Ryan, C., O'Toole, O. Tags: Neuro-oncology: CNS Lymphoma and Other Hematologic Malignancies Source Type: research

Acute ischemic stroke due to Left Ventricular Noncompaction Syndrome from a novel mutation of the Lamin A/C gene (P2.254)
Conclusion: LVNC is a risk factor for cardioembolic ischemic stroke particularly in young patients that is not well known. Patients with suspected LVNC by echocardiography should undergo cardiac MRI for confirmation and genetic testing in particular for mutations in the LMNA gene. The prognosis of those with LVNC syndrome is poor; most worsen over time and need ultimately transplantation. Close follow-up is required.Disclosure: Dr. Vongveeranonchai has nothing to disclose. Dr. Mittal has nothing to disclose. Dr. Ramos Estebanez has nothing to disclose. Dr. DeGeorgia has received personal compensation for activities with OS...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Vongveeranonchai, N., Mittal, S., Ramos Estebanez, C., De Georgia, M. Tags: Cerebrovascular Disease and Interventional Neurology: Genetics and Stroke Source Type: research

Amyloid Beta Related Angiitis in the Setting of Anticoagulation (P2.256)
Conclusion: ABRA is a rare, but treatable cause of rapid cognitive decline. Early recognition of such a rare complication of CAA can improve outcomes through offering proper immunosuppressive treatment in a timely manner. The role of amyloid PET scan as a supportive diagnostic tool for CAA and ABRA is still to be defined.Disclosure: Dr. Costa has nothing to disclose. Dr. Albadareen has nothing to disclose. Dr. Sundararajan has nothing to disclose. Dr. Burns has received research support from Janssen, Wyeth, Pfizer, Danone, Baxter, and Lilly/Avid Radiopharmaceuticals.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Costa, C., Albadareen, R., Sundararajan, J., Burns, J. Tags: Cerebrovascular Disease and Interventional Neurology: Genetics and Stroke Source Type: research

Should TCDs be routinely used for evaluating intracranial circulation for screening high risk patients prior to cardiac surgery? (P2.280)
CONCLUSIONS: Our case elucidates the possibility of a hypoperfusion stroke related to left vertebral dominantly supplying intracranial circulation in presence of bilateral significant carotid stenosis. Due to lack of previous cardio/cerebrovascular events, his carotid stenosis was deemed asymptomatic prior to cardiac surgery. We propose that intracranial collateral flow should be investigated via TCD in patients with bilateral carotid stenosis undergoing procedures with high stroke risk to assess safety and efficacy of carotid revascularization in this small but significant subset. Additional studies like acetazolamide wit...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Vu, Q., Bishop, L., Edwards, M., Tegeler, C., Sarwal, A. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research

Meningovascular Neurosyphilis Presenting as Ischemic Stroke in an HIV Positive Patient (P2.297)
CONCLUSIONS: MVNS should be considered in AIS patients without known risk factors, especially in patients who are HIV positive. Prompt treatment can halt progression of and possibly improve symptomatology. Diagnosis and improvement can be monitored with intracranial arterial wall imaging using contrast-enhanced MRI.Disclosure: Dr. Tipirneni has nothing to disclose. Dr. Gordon-Perue has nothing to disclose. Dr. DeSousa has nothing to disclose. Dr. Koch has nothing to disclose. Dr. Romano has received personal compensation for activities with NovaVision. Dr. Malik has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tipirneni, A., Gordon-Perue, G., DeSousa, K., Koch, S., Romano, J., Malik, A. Tags: Cerebrovascular Disease and Interventional Neurology: Inflammation and Immunology Source Type: research

Impact of Community Stroke Education and Comprehensive Stroke Care in South Texas (P2.300)
CONCLUSIONS: Intensified public stroke education and establishment of comprehensive stroke care significantly increased intravenous thrombolytic and endovascular treatment utilization in a South Texas border town over four fold within 18 months.Disclosure: Dr. Hassan has nothing to disclose. Dr. Tekle has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Jani has nothing to disclose. Dr. Jones-Fullingim has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hassan, A., Tekle, W., Sanchez, C., Jani, V., Jones-Fullingim, L. Tags: Cerebrovascular Disease and Interventional Neurology: Education and TIA Source Type: research

Ischemic Stroke in Pregnancy and Postpartum: A Descriptive Case Series (P1.079)
CONCLUSIONS: In our series of 19 pregnancy-associated ischemic strokes, mechanisms appeared unrelated to traditional vascular risk factors, and there was a substantial proportion of poor outcomes. Strokes were commonest in the 12 weeks postpartum, almost one third of which occurred following a miscarriage. Further exploration with a larger cohort is planned.Disclosure: Dr. Miller has nothing to disclose. Dr. Yaghi has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Willey has nothing to disclose. Dr. Elkind has received personal compensation for activities with BMS-Pfizer Partnership, Janssen Pharmaceuticals, ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Miller, E., Yaghi, S., Boehme, A., Willey, J., Elkind, M., Marshall, R. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research