Filtered By:
Source: Neurology
Condition: Thrombosis

This page shows you your search results in order of date. This is page number 10.

Order by Relevance | Date

Total 223 results found since Jan 2013.

A Novel Method for Measuring Oxidative Stress in Patients with Stroke Symptoms (S52.005)
CONCLUSIONS: These results demonstrate the ability of ORP to identify oxidative stress and amount of antioxidant reserves in a stroke population. We propose ORP monitoring as a potentially useful tool in evaluation of acute stroke patients.Disclosure: Dr. Wagner has received personal compensation for activities with Genentech, Inc. Dr. Salottolo has nothing to disclose. Dr. Fanale has received personal compensation for activities with Genentech, Inc. as a speaker. Dr. Whaley has nothing to disclose. Dr. McCarthy has nothing to disclose. Luoxis Diagnostics, Inc,
Source: Neurology - April 8, 2015 Category: Neurology Authors: Wagner, J., Salottolo, K., Fanale, C., Whaley, M., McCarthy, K., BarOr, D. Tags: General Neurology: Neural Networks and Neuromodulation Source Type: research

Balancing access and quality in comprehensive stroke care
The establishment of stroke units and stroke centers has transformed the inpatient care of cerebrovascular disease and resulted in improved outcomes for patients hospitalized with stroke. Studies show that organized care as part of a stroke unit results in reduced mortality and disability after stroke,1 and that patients hospitalized at primary stroke centers have lower mortality and are more likely to receive thrombolytic therapy.2
Source: Neurology - March 23, 2015 Category: Neurology Authors: Kelly, A. G., Attia, J. Tags: All Health Services Research, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, All epidemiology EDITORIALS Source Type: research

Thromboembolic events in Fabry disease and the impact of factor V Leiden
Conclusion: This observational study confirms that patients with FD have a high risk of clinically relevant thromboembolic events, which could be aggravated by a concurrence of FVL. ERT might be of benefit in preventing vascular events in patients with FD. The latter observation needs confirmation, however, by randomized and controlled clinical trials.
Source: Neurology - March 9, 2015 Category: Neurology Authors: Lenders, M., Karabul, N., Duning, T., Schmitz, B., Schelleckes, M., Mesters, R., Hense, H.-W., Beck, M., Brand, S.-M., Brand, E. Tags: All Clinical Neurology, Metabolic disease (inherited), All Cerebrovascular disease/Stroke, Cohort studies, Incidence studies ARTICLE Source Type: research

Clinical Reasoning: An unusual case of subacute encephalopathy
A 52-year-old previously healthy man presented with 8 months of progressive cognitive decline. He complained of months of confusion, fatigue, depression, hypersomnolence, headaches, and, subsequently, urinary incontinence and unsteady gait. His family reported that he spoke of his deceased mother as if she were alive. His executive deficits progressed, leading to termination of his employment and a motor vehicle accident. He was evaluated and treated in Morocco before presenting to our institution for further care.
Source: Neurology - February 9, 2015 Category: Neurology Authors: Parikh, N., Merkler, A. E., Cheng, N. T., Baradaran, H., White, H., Leifer, D. Tags: All Cerebrovascular disease/Stroke, Arteriovenous malformation, Cerebral venous thrombosis RESIDENT AND FELLOW SECTION Source Type: research

Teaching NeuroImages: Cortical blindness following acute obstructive hydrocephalus by a colloid cyst
A 46-year-old woman was admitted for acute headache, postseizure confusion, and visual loss. Urgent head CT scan showed obstructive hydrocephalus due to a colloid cyst (figure 1). External ventricular drains inserted emergently demonstrated CSF under pressure, above 40 mm H2O. MRI confirmed the suspected diagnosis of a colloid cyst and highlighted bilateral occipital lobe infarcts (figure 2). CT angiography showed no thrombosis of the posterior cerebral arteries (PCAs). After neurosurgical excision of the colloid cyst, the patient remained blind. The presumed mechanism of infarction was acute compression of the PCAs agains...
Source: Neurology - February 9, 2015 Category: Neurology Authors: Champeaux, C., Grivas, A. Tags: Hydrocephalus, Stroke in young adults, MRI, Clinical neurology examination, Visual loss RESIDENT AND FELLOW SECTION Source Type: research

Teaching NeuroImages: Magnetic resonance susceptibility effect for acute isolated cortical vein thrombosis
A 38-year-old woman using hormonal contraception presented with right-sided abdominal and arm clonic seizures, right hemiparesis, hypesthesia, and nausea. She denied headache. D-dimers were 350 ng/mL (laboratory reference ≤500 ng/mL). CT showed a small left parietal hemorrhagic infarct with adjacent hyperdense cortical vein (figure 1). MRI 15 hours after onset showed magnetic susceptibility effect on susceptibility-weighted imaging (SWI, figure 2). Isolated cortical vein thrombosis is present in 5% of patients with cerebral venous thrombosis (CVT).1 Negative D-dimer and absence of headache does not exclude CVT1 and SWI ...
Source: Neurology - November 10, 2014 Category: Neurology Authors: Pikija, S., Unterkreuter, P., Knoflach, M. Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, All Epilepsy/Seizures RESIDENT AND FELLOW SECTION Source Type: research

Teaching NeuroImages: Extracranial internal carotid artery aneurysm causing embolic stroke
A 42-year-old man with no history of trauma experienced acute numbness in his right arm and leg. A pulsating left cervical tumor was noted on clinical examination. Carotid ultrasound demonstrated significant widening of the left proximal internal carotid artery (ICA) and a large nonocclusive hypoechoic structure compatible with an aneurysm and intraluminal thrombus (figure, B, D, and E). MRI confirmed a fusiform extracranial ICA aneurysm and showed a left-sided small embolic stroke (figure, A and C). The patient underwent anticoagulation with low-molecular-weight heparin and eventually surgical treatment (i.e., resection a...
Source: Neurology - July 14, 2014 Category: Neurology Authors: Barlinn, K., Kepplinger, J., Puetz, V., Bodechtel, U. Tags: Stroke in young adults, MRI, Ultrasound, Embolism RESIDENT AND FELLOW SECTION Source Type: research

Risk of recurrent thromboembolic phenomena after ischemic stroke in patients with malignancy
In the 1860s, Trousseau first described the association between cancer and a hypercoagulable state.1 Ironically, he later diagnosed himself with phlebitis and predicted his own death from pancreatic cancer. Secretion of procoagulants by tumor cells, vascular damage secondary to immune response, and iatrogenic injury from chemotherapeutic agents, radiotherapy, and in-dwelling catheters, among other mechanisms, may contribute to hypercoagulability in the setting of cancer.2 This places oncology patients at high risk of cerebrovascular phenomena, which frequently leads to patients' initial diagnosis.3 Despite this well-define...
Source: Neurology - June 30, 2014 Category: Neurology Authors: Starke, R. M. Tags: EDITORIALS Source Type: research

Recurrent thromboembolic events after ischemic stroke in patients with cancer
Conclusions: Patients with acute ischemic stroke in the setting of active cancer (especially adenocarcinoma) face a substantial short-term risk of recurrent ischemic stroke and other types of thromboembolism.
Source: Neurology - June 30, 2014 Category: Neurology Authors: Navi, B. B., Singer, S., Merkler, A. E., Cheng, N. T., Stone, J. B., Kamel, H., Iadecola, C., Elkind, M. S. V., DeAngelis, L. M. Tags: All Cerebrovascular disease/Stroke, All Oncology, Cohort studies, Infarction ARTICLE Source Type: research

Thrombolytic therapy for stroke in patients with preexisting cognitive impairment
Conclusions: Ischemic stroke patients with PSCI should receive rtPA if they are eligible. This conclusion cannot be extended to severe cognitive impairment or severe strokes. Classification of evidence: This study provides Class IV evidence that in patients with PSCI presenting with acute ischemic stroke, IV rtPA improves outcomes.
Source: Neurology - June 9, 2014 Category: Neurology Authors: Murao, K., Leys, D., Jacquin, A., Kitazono, T., Bordet, R., Bejot, Y., Kimura, K., Godefroy, O., Wakisaka, Y., Moulin, S., Ago, T., Sibon, I., Bombois, S., Mas, J.-L., Henon, H., Pasquier, F., Giroud, M., Cordonnier, C., Okada, Y., On behalf of the OPHELI Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, MCI (mild cognitive impairment), Infarction ARTICLE Source Type: research

Clinical Reasoning: A 24-year-old woman with progressive headache and somnolence
A 24-year-old woman presented with progressive somnolence and headache following 2 days of nausea and vomiting. She had a history of developmental delay, attention-deficit disorder, and remote seizures. Medications included combined estrogen-progestin oral contraceptives. On presentation, she was afebrile, somnolent but arousable, groaning incoherently, and unable to follow commands. Optic disc margins were blurred bilaterally. Gaze was midline and deviated downward with restricted spontaneous upward gaze but full lateral gaze. She moved the right side less briskly than the left.
Source: Neurology - June 2, 2014 Category: Neurology Authors: Bhattacharyya, S., Berkowitz, A. L., Jha, R. M. Tags: All Headache, Stroke in young adults, Coma, Critical care, Cerebral venous thrombosis RESIDENT AND FELLOW SECTION Source Type: research

Pearls & Oy-sters: Polycythemia vera presenting with ischemic strokes in multiple arterial territories
Thrombosis is the presenting symptom in 20% of patients with polycythemia vera (PV); 70% of these thrombotic events are TIAs or strokes.
Source: Neurology - May 19, 2014 Category: Neurology Authors: Billakota, S., El Husseini, N. Tags: MRI, All Clinical Neurology, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

PKC-{delta} and Akt Signaling in Reduced Apoptosis by Ethanol after Transient Ischemic Stroke (P1.100)
CONCLUSIONS: Our study suggests that ethanol administration following ischemic stroke modulates the gene and protein profile by increasing expression of anti-apoptotic Akt and decreases the pro-apoptotic PKC-. This ultimately results in a decrease in neuronal apoptosis, thus conferring neuroprotection.Disclosure: Dr. Hafeez has nothing to disclose. Dr. Geng has nothing to disclose. Dr. Guthikonda has nothing to disclose. Dr. Ding has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hafeez, A., Geng, X., Guthikonda, M., Ding, Y. Tags: Cerebrovascular Disease and Interventional Neurology: Translational Science Source Type: research

Safety And Efficacy Of Fondaparinux For Venous Thromboembolism Prophylaxis After Acute Ischemic Stroke (P1.110)
CONCLUSIONS: VTE prophylaxis with fondaparinux for acute ischemic stroke was associated with low rates of major hemorrhagic complications and symptomatic VTE events during hospital admission. Fondaparinux may be considered safe and efficacious for VTE prophylaxis after acute ischemic stroke but requires prospective validation.Study Supported by:N/ADisclosure: Dr. Ramanathan has nothing to disclose. Dr. Malhotra has nothing to disclose. Dr. Hackett has nothing to disclose. Dr. Tian has nothing to disclose. Dr. Quigley has nothing to disclose. Dr. Wright has nothing to disclose. Dr. Wong has nothing to disclose. Dr. Tayal ha...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramanathan, S., Malhotra, K., Hackett, C., Tian, M., Quigley, M., Wright, D., Wong, C., Tayal, A. Tags: Cerebrovascular Disease and Interventional Neurology: Antiplatelet Agents and Miscellaneous Source Type: research

Comparison of Thrombolytic Treatment for Acute Ischemic Stroke Pre- and Post-Telemedicine Implementation in the Spoke Hospital Setting (PL1.002)
CONCLUSIONS: Results from the study demonstrate that the percent of patients treated with rtPA with telemedicine increased more than 50% as compared to the pre-telemedicine time period. Smaller hospitals showed the most significant increase in rtPA treatment rate. This finding supports previous findings that telemedicine improves appropriate use of thrombolytic treatment for AIS patients and highlights the impact in smaller hospital settings.Study Supported by: Genentech Inc.Disclosure: Dr. William has received personal compensation for activities with Premier Inc. Dr. Chen has received personal compensation for activities...
Source: Neurology - April 9, 2014 Category: Neurology Authors: William, M., Chen, E., Krukas, M., Tayama, D., Ernst, F., Wagner, J. Tags: Contemporary Clinical Issues Plenary Session Source Type: research