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Source: Neurology
Condition: Epilepsy

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Total 139 results found since Jan 2013.

Quality of Life in Liver Transplant Patients with Neurologic Complications. (P4.031)
Conclusions: Our analysis shows that neurological complications worsen the quality of life of liver transplant patients. Especially regarding perception of health, ability to function independently due to physical and mental health limitations. Pain is a limiting condition in this group. Transplant patients who suffer neurological complications should be carefully followed up to reduce the impact on quality of life, in order to promote the ultimate goal of transplant.Disclosure: Dr. Gonzalez Toledo has nothing to disclose. Dr. Calle has received personal compensation for activities with UCB Pharma. Dr. Pagani Cassara has n...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Gonzalez Toledo, M., Calle, A., Pagani Cassara, F., Tamargo, A., Thomson, A., Nadile, D., Gruz, F., Sinay, V. Tags: General Neurology III Source Type: research

Neurology Telemedicine Interest in Arkansas (P4.038)
CONCLUSIONS: Interest in teleneurology was strong among patients at our university neurology clinic, likely due to long distances traveled by many patients, expense of travel and transportation difficulties created by neurologic illness. Illness-related problems may include physical difficulty with travel (e.g., patients with MS, ALS, or Parkinson’s disease who have mobility problems) or those with restrictions on driving (epilepsy). Teleneurology may be a viable option for many of these patients.Study Supported by: Departmental Research FundsDisclosure: Dr. Greenfield has received personal compensation for activitie...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Greenfield, L., Bashiri, M., Kovvuru, S. Tags: General Neurology III Source Type: research

Voltage Gated Calcium Channels Antibody-Associated Autoimmune Encephalitis (P5.228)
ConclusionThis case demonstrates a correlation between a high titer of VGCC antibodies and autoimmune encephalitis. Our patient's initial improvement with steroids and plasma exchange in the face of a negative CT and PET suggests a primary autoimmune process rather than a paraneoplastic etiology, though we admit that it is premature to rule out remission and we will continue to follow herDisclosure: Dr. Alwaki has nothing to disclose. Dr. Lugo has nothing to disclose. Dr. Goshgarian has nothing to disclose. Dr. Ahmad has nothing to disclose. Dr. Hefzy has nothing to disclose. Dr. Mitsias has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Alwaki, A., Lugo, A., Goshgarian, C., Ahmad, O., Hefzy, H., Mitsias, P. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Creutzfeldt-Jakob Disease and Subacute Encephalopathies Source Type: research

Cerebral Hyperperfusion and Vasodilatory Changes in Acute Seizure - Report of Three Cases (P6.193)
Conclusion:Acute seizure can induce changes in cerebral perfusion and is essential to recognize these changes to distinguish seizure as stroke mimic. Our experience shows cerebral hyperperfusion and seems to correlate with the hypermetabolic profile of seizure focus. Enlarged caliber of cortical vessels in the areas of hyperperfusion should alert for acute seizure induced changes. The vasodilatory changes of the cortical branches near seizure focus have never been reported.Study Supported by: noneDisclosure: Dr. Krishnaiah has nothing to disclose. Dr. Said Said has nothing to disclose. Dr. Thamburaj has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Krishnaiah, B., Said Said, S., Thamburaj, K. Tags: Epilepsy and Clinical Neurophysiology (EEG): MEG and Imaging Source Type: research

Utility of CT Perfusion (CTP) Imaging in Seizures: A Retrospective Analysis and Literature Review (I1-1.008)
Conclusions: CTP is a valuable test to help differentiate strokes and seizures. CTP abnormalities are common in patients presenting to the ED with seizures. Particular attention to the patterns of CTP changes increases the specificity of this test. CTP imaging is now routinely available and has a shorter acquisition time than studies such as MRI or EEG making it uniquely useful for seizures. In addition, CTP may aid in targeting certain areas for biopsy in suspected pathologies like tumors and may prevent unnecessary thrombolysis. Given that cerebral blood flow mechanics is a dynamic phenomenon, the timing of CT perfusion ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Khaku, A., Hedna, V., Waters, M. Tags: Temporal Lobe Epilepsy and Febrile Seizures Poster Presentations Source Type: research

The Role of Toll-Like Receptor 3 in Epileptogenesis (I1-2.001)
Conclusion:These preliminary results -in a still ongoing study- indicate a central involvement of seizure induction (epileptogenesis) by TLR3 and provide evidence for future research and possibly drug development to finally change the treatment paradigm of epilepsy from symptomatic seizure control to curable prevention of seizure development.Disclosure: Dr. Benninger has nothing to disclose. Dr. Gross has nothing to disclose. Dr. Steiner has received personal compensation for activities with Actelion and Hoffman La Roche. Dr. Offen has nothing to disclose. Dr. Okun has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Benninger, F., Gross, A., Steiner, I., Offen, D., Okun, E. Tags: Temporal Lobe Epilepsy and Febrile Seizures Data Blitz Presentations Source Type: research

New Onset Seizures in Elderly:Clinical Presentation and Etiology of First Ever Seizure (P3.235)
CONCLUSIONS: The most common etiology of seizures in elderly was cerebro-vascular disease. Commonest presentation was focal seizureStudy Supported by: nilDisclosure: Dr. Shariff has nothing to disclose. Dr. Alhameed has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Shariff, E., Alhameed, M. Tags: Epilepsy and Clinical Neurophysiology: Clinical Manifestations Source Type: research

When Should We Treat Periodic Lateralized Epileptiform Discharges (PLEDS) (P5.061)
CONCLUSIONS:Mortality was unchanged with or without treatment of patients with PLEDs on cEEG, although the extent of treatment was highly variable. PLEDs in the absence of structural lesion can be ictal, interictal or postictal finding on EEG and resulted in a higher mortality rate. Larger, prospective studies that use neuroimaging as part of a decision tree can provide more definitive guidance.Disclosure: Dr. Solaiman has nothing to disclose. Dr. Memon has nothing to disclose. Dr. Basha has nothing to disclose. Dr. Avedian has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Solaiman, A., Memon, A., Basha, M., Avedian, L. Tags: Epilepsy and Clinical Neurophysiology: EEG Source Type: research

Incidence and Predictors of Unprovoked Seizures after Stroke (S12.007)
Conclusions: The incidence of unprovoked seizures is among the highest reported in patients with first-ever stroke. The prospective design is a possible explanation. Older age, cortical lesion and higher functional disability are predictors of unprovoked seizures.Study supported by Regione Emilia-Romagna, Progetto Strategico "Stroke Care".The Epistroke Group: L.Delaj, R.D'Alessandro, S.Beretta, D.Consoli, V.Crespi, C.Gandolfo, G.Greco, A.LaNeve, M.Manfredi, P. Messina, R.Musolino, L.Provinciali, M.Santangelo, L.M.Specchio, G.ZaccaraDisclosure: Dr. Beghi has received personal compensation for activities with GlaxoSmithKlyne...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Beghi, E. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors Source Type: research

Brain Herniation Due To Mitochondrial Encephalomyopathy, Lactic Acidosis, Stroke Like Events (MELAS) With 3256 Mutation Responsive To Decompressive Craniotomy (P6.257)
CONCLUSIONS:In our MELAS case, decompessive craniotomy is life saving for brain herniation due to SLE. Headache refractory to narcotics and increased lactic acid level are early warning signs of acute SLE since MRI can be normal. Steriod might be indicated for acute treatment of cortical edema.Disclosure: Dr. Cui has nothing to disclose. Dr. Schwendimann has received research support from Lundbeck.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Cui, C., Schwendimann, R. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Stroke and Non Convulsive Status Epilepticus. A Topographic and Prognosis Description. (P5.112)
Conclusions: Even though this is a preliminary study, NCSE seems to be a serious complication with a high impact on the prognosis of acute stroke. The association between stroke and NCSE appears to be more frequent in men, right hemisphere localization, and curiously, our population involved the frontal lobe in 100% of the cases. Stroke in the anterior cerebral artery territory and exposure to cefepime suggested a lack of initial response to antiepileptic treatment with higher mortality. Recognizing these variables may be useful to define more aggressive antiepileptic treatments in this population.Disclosure: Dr. Muñ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Munoz Giacomelli, F., Calle, A., Gonzalez Toledo, M., Pagani Cassara, F., Tamargo, A., Thomson, A., Nadile, D., Klein, F. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Epilepsy and Cancer: Ancient Problem in a Top Mortality Illness (P3.313)
CONCLUSIONS: Seizures in patients with cancer is a frequent comorbid condition with a high mortality rate, further studies are required to study the efficacy and security of AED and other forms of treatment.Study Supported by: NoneDisclosure: Dr. Cacho Diaz has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Cacho Diaz, B. Tags: Neurologic Complications of Cancer Source Type: research

Restricted Diffusion Imaging In Active Seizure: A Case Report (P6.306)
CONCLUSION: Although Diffusion weighted imaging is commonly associated with ischemia, several pathophysiologies such as epilepsy, CNS infections, demyelinating disease, malignancies, and others can present similarly.Disclosure: Dr. Subei has nothing to disclose. Dr. Eggenberger has received personal compensation for activities with Biogen Idec, Genzyme Corporation, Novartis, Teva, Allergan, Serono, Berlex, Acorda, and PRIME. Dr. Eggenberger has received research support from Allergan, Inc., Biogen, Teva, Novartis, and Genzyme.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Subei, A., Eggenberger, E. Tags: Neuro-ophthalmology/Neuro-otology II Source Type: research

Efficacy of Lacosamide in Epilepsia Partialis Continua (P4.254)
CONCLUSIONS:Use of lacosamide in treatment of status epilepticus (SE) has been reported in 136 episodes out of which 31% were focal SE. The treatment protocol for focal SE is not well defined and often leads to polypharmacy and additive side effects. Lacosamide was chosen in our case because of previously suggested synergistic effects with levetiracetam, favorable pharmacokinetic attributes with no drug/drug interactions, and favorable adverse event profile including little or no sedation. Its use led to rapid resolution of seizures and avoidance of ICU related complications. The use of lacosamide in EPC especially as a co...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Jadhav, D., Birnbaum, D., Burger, K., Koubeissi, M. Tags: Epilepsy and Clinical Neurophysiology (EEG): Status Epilepticus Source Type: research

Epilepsia Partialis Continua Secondary To Ischemic Stroke, Responsive To The Combination Of Levetiracetam And Lacosamide (P4.255)
CONCLUSIONS: EPC represents a condition commonly refractory to AED. We report two cases of EPC secondary to subacute and chronic IS that showed responsiveness to the combination of levetiracetam and lacosamide. Further evaluation of this AED combination in treating this difficult condition is needed.Disclosure: Dr. Thompson has nothing to disclose. Dr. Murr has nothing to disclose. Dr. Fayad has received research support from the National Institute of Neurological Disorders and Stroke, and St Jude Medical.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Thompson, R., Murr, N., Fayad, P. Tags: Epilepsy and Clinical Neurophysiology (EEG): Status Epilepticus Source Type: research